التفاصيل البيبلوغرافية
| العنوان: |
One-year outcomes in cardiogenic shock triggered by ventricular arrhythmia: An analysis of the FRENSHOCK multicenter prospective registry |
| المؤلفون: |
Cherbi, M. (Miloud), Roubille, F. (François), Lamblin, N. (Nicolas), Bonello, L. (Laurent), Leurent, G. (Guillaume), Levy, B. (Bruno), Elbaz, M. (Meyer), Champion, S. (Sebastien), Lim, P. (Pascal), Schneider, F. (Francis), Cariou, A. (Alain), Khachab, H. (Hadi), Bourenne, J. (Jeremy), Seronde, M. (Marie-France), Schurtz, G. (Guillaume), Harbaoui, B. (Brahim), Vanzetto, G. (Gerald), Quentin, C. (Charlotte), Delabranche, X. (Xavier), Aissaoui, N. (Nadia), Combaret, N. (Nicolas), Tomasevic, D. (Danka), Marchandot, B. (Benjamin), Lattuca, B. (Benoit), Henry, P. (Patrick), Gerbaud, E. (Edouard), Bonnefoy, E. (Eric), Puymirat, E. (Etienne), Maury, P. (Philippe), Delmas, C. (Clément) |
| سنة النشر: |
2023 |
| مصطلحات موضوعية: |
Sciences du Vivant [q-bio]/Biotechnologies |
| الوصف: |
Background: Cardiogenic shock (CS) is a life-threatening condition carrying poor prognosis, potentially triggered by ventricular arrhythmia (VA). Whether the occurrence of VA as trigger of CS worsens the prognosis compared to non-VA triggers remains unclear. The aim of this study was to evaluate 1-year outcomes [mortality, heart transplantation, ventricular assist devices (VAD)] between VA-triggered and non-VA-triggered CS. Methods: FRENSHOCK is a prospective multicenter registry including 772 CS patients from 49 centers. One to three triggers can be identified in the registry (ischemic, mechanical complications, ventricular/supraventricular arrhythmia, bradycardia, iatrogenesis, infection, non-compliance). Baseline characteristics, management and 1-year outcomes were analyzed according to the VA-trigger in the CS population. Results: Within 769 CS patients included, 94 were VA-triggered (12.2%) and were compared to others. At 1 year, although there was no mortality difference [42.6 vs. 45.3%, HR 0.94 (0.67-1.30), p = 0.7], VA-triggered CS resulted in more heart transplantations and VAD (17 vs. 9%, p = 0.02). Into VA-triggered CS group, though there was no 1-year mortality difference between ischemic and non-ischemic cardiomyopathies [42.5 vs. 42.6%, HR 0.97 (0.52-1.81), p = 0.92], non-ischemic cardiomyopathy led to more heart transplantations and VAD (25.9 vs. 5%, p = 0.02). Conclusion: VA-triggered CS did not show higher mortality compared to other triggers but resulted in more heart transplantation and VAD at 1 year, especially in non-ischemic cardiomyopathy, suggesting the need for earlier evaluation by advanced heart failure specialized team for a possible indication of mechanical circulatory support or heart transplantation. Clinical trial registration: https://clinicaltrials.govTest, identifier NCT02703038. Keywords: cardiogenic shock; epidemiology; prognosis; ventricular arrhythmia; ventricular tachycardia. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.3389/fcvm.2023.1092904/full |
| حقوق: |
Paternité - Pas d'utilisation commerciale [CC] [BY] [NC] ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edsbas.94F8709E |
| قاعدة البيانات: |
BASE |
