المؤلفون: Yuan, Yuan, Ju, Young Seok, Kim, Youngwook, Li, Jun, Wang, Yumeng, Yoon, Christopher J, Yang, Yang, Martincorena, Inigo, Creighton, Chad J, Weinstein, John N, Xu, Yanxun, Han, Leng, Kim, Hyung-Lae, Nakagawa, Hidewaki, Park, Keunchil, Campbell, Peter J, Liang, Han

المساهمون: Borg, Åke, Creator, Ringnér, Markus, Creator, Staaf, Johan, Creator

المصدر: Nature Genetics. 52(3):342-352

مصطلحات موضوعية: Cell Cycle/genetics, DNA Copy Number Variations, DNA Repair/genetics, DNA, Mitochondrial/genetics, Genome, Human/genetics, Humans, Mutation, Neoplasms/genetics, Oxidative Phosphorylation, Sequence Analysis, RNA, Whole Genome Sequencing, Medicin och hälsovetenskap, Medicinska och farmaceutiska grundvetenskaper, Medicinsk genetik, Medical and Health Sciences, Basic Medicine, Medical Genetics

الوصول الحر: https://lup.lub.lu.se/record/8f1c62ab-fa08-4872-abf2-d33f162c1225Test
http://dx.doi.org/10.1038/s41588-019-0557-xTest

المؤلفون: Sørensen, Simon Grund, Shrikhande, Amruta, Poulsgaard, Gustav Alexander, Christensen, Mikkel Hovden, Bertl, Johanna, Laursen, Britt Elmedal, Hoffmann, Eva R, Pedersen, Jakob Skou

المصدر: Sørensen , S G , Shrikhande , A , Poulsgaard , G A , Christensen , M H , Bertl , J , Laursen , B E , Hoffmann , E R & Pedersen , J S 2023 , ' Pan-cancer association of DNA repair deficiencies with whole-genome mutational patterns ' , eLife , vol. 12 , e81224 . https://doi.org/10.7554/elife.81224Test

مصطلحات موضوعية: BRCA1 Protein/genetics, BRCA2 Protein/genetics, DNA Helicases/genetics, DNA Repair-Deficiency Disorders, DNA Repair/genetics, Humans, Male, Mutation, Neoplasms/genetics, Nuclear Proteins/genetics, Transcription Factors/genetics, predictive modelling, DNA damage response, mutational signatures, personalised medicine, repair deficiency

العلاقة: https://pure.au.dk/portal/da/publications/pancancer-association-ofTest-dna-repair-deficiencies-with-wholegenome-mutational-patterns(6d841269-ef5f-41e2-a050-6f671e6994dd).html

الإتاحة: https://doi.org/10.7554/elife.81224Test
https://pure.au.dk/portal/da/publications/pancancer-association-ofTest-dna-repair-deficiencies-with-wholegenome-mutational-patterns(6d841269-ef5f-41e2-a050-6f671e6994dd).html

المؤلفون: Simon Grund Sørensen, Amruta Shrikhande, Gustav Alexander Poulsgaard, Mikkel Hovden Christensen, Johanna Bertl, Britt Elmedal Laursen, Eva R Hoffmann, Jakob Skou Pedersen

المصدر: Sørensen, S G, Shrikhande, A, Poulsgaard, G A, Christensen, M H, Bertl, J, Laursen, B E, Hoffmann, E R & Pedersen, J S 2023, ' Pan-cancer association of DNA repair deficiencies with whole-genome mutational patterns ', eLife, vol. 12 . https://doi.org/10.7554/eLife.81224Test
Sørensen, S G, Shrikhande, A, Poulsgaard, G A, Christensen, M H, Bertl, J, Laursen, B E, Hoffmann, E R & Pedersen, J S 2023, ' Pan-cancer association of DNA repair deficiencies with whole-genome mutational patterns ', eLife, vol. 12, e81224 . https://doi.org/10.7554/elife.81224Test

مصطلحات موضوعية: Male, General Immunology and Microbiology, General Neuroscience, DNA Helicases/genetics, repair deficiency, personalised medicine, Transcription Factors/genetics, mutational signatures, General Medicine, DNA damage response, BRCA2 Protein/genetics, Neoplasms/genetics, DNA Repair-Deficiency Disorders, General Biochemistry, Genetics and Molecular Biology, Nuclear Proteins/genetics, DNA Repair/genetics, Mutation, Humans, BRCA1 Protein/genetics, predictive modelling

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd8fdd0c0855124ac5e59edd15de56b8Test
https://pure.au.dk/portal/da/publications/pancancer-association-ofTest-dna-repair-deficiencies-with-wholegenome-mutational-patterns(6d841269-ef5f-41e2-a050-6f671e6994dd).html

المؤلفون: Antonio Rodriguez-Calero, John Gallon, Dilara Akhoundova, Sina Maletti, Alison Ferguson, Joanna Cyrta, Ursula Amstutz, Andrea Garofoli, Viola Paradiso, Scott A. Tomlins, Ekkehard Hewer, Vera Genitsch, Achim Fleischmann, Erik Vassella, Elisabeth J. Rushing, Rainer Grobholz, Ingeborg Fischer, Wolfram Jochum, Gieri Cathomas, Adeboye O. Osunkoya, Lukas Bubendorf, Holger Moch, George Thalmann, Charlotte K. Y. Ng, Silke Gillessen, Salvatore Piscuoglio, Mark A. Rubin

المساهمون: University of Zurich, Piscuoglio, Salvatore, Rubin, Mark A

المصدر: Nature communications, vol. 13, no. 1, pp. 2400
Rodriguez-Calero, Antonio; Gallon, John; Akhoundova, Dilara; Maletti, Sina; Ferguson, Alison; Cyrta, Joanna; Amstutz, Ursula; Garofoli, Andrea; Paradiso, Viola; Tomlins, Scott A; Hewer, Ekkehard; Genitsch, Vera; Fleischmann, Achim; Vassella, Erik; Rushing, Elisabeth J; Grobholz, Rainer; Fischer, Ingeborg; Jochum, Wolfram; Cathomas, Gieri; Osunkoya, Adeboye O; ... (2022). Alterations in homologous recombination repair genes in prostate cancer brain metastases. Nature Communications, 13(1), p. 2400. Springer Nature 10.1038/s41467-022-30003-5 <http://dx.doi.org/10.1038/s41467-022-30003-5Test>

مصطلحات موضوعية: Male, Multidisciplinary, Brain Neoplasms, Prostatic Neoplasms, Recombinational DNA Repair, General Physics and Astronomy, Brain Neoplasms/drug therapy, Brain Neoplasms/genetics, Humans, Mutation, Poly(ADP-ribose) Polymerase Inhibitors/pharmacology, Poly(ADP-ribose) Polymerase Inhibitors/therapeutic use, Prostatic Neoplasms/drug therapy, Prostatic Neoplasms/genetics, Recombinational DNA Repair/genetics, 610 Medicine & health, 1600 General Chemistry, General Chemistry, Poly(ADP-ribose) Polymerase Inhibitors, General Biochemistry, Genetics and Molecular Biology, 3100 General Physics and Astronomy, 1300 General Biochemistry, Genetics and Molecular Biology, 10049 Institute of Pathology and Molecular Pathology, 570 Life sciences, biology

وصف الملف: Rodriguez_NatComm_2022.pdf - application/pdf; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d339acb753118a030885e55b80a56cbbTest
https://www.zora.uzh.ch/id/eprint/222097Test/

المساهمون: College of Medicine, Dept. of Pharmacology, Braun, Rao, Mollet, Schapiro, Daugeron, Tan, Gribouval, Boyer, Revy, Jobst-Schwan, Schmidt, Lawson, Schanze, Ashraf, Ullmann, Hoogstraten, Boddaert, Collinet, Martin, Liger, Lovric, Furlano, Guerrera, Sanchez-Ferras, Hu, Boschat, Sanquer, Menten, Vergult, De Rocker, Airik, Hermle, Shril, Widmeier, Gee HY, Choi, Sadowski, Pabst, Warejko, Daga, Basta, Matejas, Scharmann, Kienast, Behnam, Beeson, Begtrup, Bruce, Ch'ng, Lin, Chang, Chen, Cho, Gaffney, Gipson, Hsu, Kari, Ke, Kiraly-Borri, Lai, Lemyre, Littlejohn, Masri, Moghtaderi, Nakamura, Ozaltin, Praet, Prasad, Prytula, Roeder, Rump, Schnur, Shiihara, Sinha, Soliman, Soulami, Sweetser, Tsai, Topaloglu, Vester, Viskochil, Vatanavicharn, Waxler, Wierenga, Wolf, Wong, Leidel, Truglio, Dedon, Poduri, Mane, Lifton, Bouchard, Kannu, Chitayat, Magen, Callewaert

مصطلحات موضوعية: Animals, Apoptosis/genetics, CRISPR-Cas Systems, Carrier Proteins/genetics, Cell Movement, Cytoskeleton/ultrastructure, DNA Repair/genetics, Endoplasmic Reticulum Stress/genetics, Gene Knockout Techniques, Hernia, Hiatal/genetics, Humans, Intracellular Signaling Peptides and Proteins/deficiency, Intracellular Signaling Peptides and Proteins/genetics, Metalloendopeptidases/deficiency, Metalloendopeptidases/genetics, Mice, Microcephaly/genetics, Models, Molecular, Multiprotein Complexes/genetics, Mutation, Nephrosis/genetics, Nephrotic Syndrome/genetics, Nephrotic Syndrome/pathology, Podocytes/metabolism, Podocytes/ultrastructure, Protein Conformation, Protein-Serine-Threonine Kinases/deficiency, Protein-Serine-Threonine Kinases/genetics

العلاقة: NATURE GENETICS; J02294; OAK-2017-05768; https://ir.ymlib.yonsei.ac.kr/handle/22282913/161090Test; T201704054; NATURE GENETICS, Vol.49(10) : 1529-1538, 2017

الإتاحة: https://doi.org/10.1038/ng.3933Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/161090Test

المؤلفون: María del Carmen Conde-Rubio, Gilles Dubuis, Christian Widmann, Daniel Constantin

المصدر: The FEBS journal, vol. 289, no. 3, pp. 808-831

مصطلحات موضوعية: APOBEC, DNA End-Joining Repair, DNA Repair, DNA repair, DNA damage, Nucleolus, Cell Nucleolus/genetics, Cytidine Deaminase/genetics, DNA Breaks, Double-Stranded/drug effects, DNA Damage/drug effects, DNA Damage/genetics, DNA End-Joining Repair/genetics, DNA Repair/drug effects, DNA Repair/genetics, Etoposide/pharmacology, Gene Expression Regulation/drug effects, Genome, Human/genetics, Homologous Recombination/genetics, Humans, Multigene Family/genetics, Mutagens/pharmacology, Mutation/genetics, Tumor Suppressor Protein p53/genetics, APOBEC3C, cancer biology, nucleolus, p53, Biology, Biochemistry, Cytidine Deaminase, DNA Breaks, Double-Stranded, Homologous Recombination, Molecular Biology, Etoposide, Genome, Human, Cell Biology, Cell biology, Non-homologous end joining, genomic DNA, Gene Expression Regulation, Multigene Family, Mutation, Human genome, Tumor Suppressor Protein p53, Homologous recombination, Cell Nucleolus, DNA Damage, Mutagens

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed082bf9274bb2db8cd80d43f41b48dcTest
https://serval.unil.ch/notice/serval:BIB_549304C0D4F3Test

المؤلفون: Lee, Kyung-Hun, Min, Hye Sook, Han, Sae-Won, Oh, Do-Youn, Lee, Se-Hoon, Kim, Dong-Wan, Im, Seock-Ah, Chung, Doo Hyun, Kim, Young Tae, Kim, Tae-You, Heo, Dae Seog, Bang, Yung-Jue, Sung, Sook Whan, Kim, Joo Hyun

المساهمون: 이경훈, 민혜숙, 한새원, 오도윤, 이세훈, 김동완, 임석아, 정두현, 김용태, 김태유, 허대석, 방영주, 성숙환, 김주현

مصطلحات موضوعية: Adult, Aged, 80 and over, Carcinoma, Non-Small-Cell Lung/*genetics/pathology/surgery, DNA Repair/genetics, DNA-Binding Proteins/*genetics, Endonucleases/*genetics, Female, Gene Expression Regulation, Neoplastic, Humans, Immunohistochemistry, Lung Neoplasms/*genetics/pathology/surgery, Male, Middle Aged, Mutation, Neoplasm Recurrence, Local, Neoplasm Staging, Receptor, Epidermal Growth Factor/*genetics, Risk Factors, Survival Analysis, Tobacco Smoke Pollution

العلاقة: Lung Cancer. 200860(3):401-407; 0169-5002 (Print); http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18036700Test; http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6T9C-4R718BD-2-5&_cdi=5111&_user=168665&_orig=search&_coverDate=06%2F30%2F2008&_sk=999399996&view=c&wchp=dGLbVtb-zSkWA&md5=b178805252ae645f750e46d49feb7944&ie=/sdarticle.pdfTest; http://hdl.handle.net/10371/68381Test

الإتاحة: https://doi.org/10.1016/j.lungcan.2007.10.014Test
http://hdl.handle.net/10371/68381Test
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18036700Test
http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6T9C-4R718BD-2-5&_cdi=5111&_user=168665&_orig=search&_coverDate=06%2F30%2F2008&_sk=999399996&view=c&wchp=dGLbVtb-zSkWA&md5=b178805252ae645f750e46d49feb7944&ie=/sdarticle.pdfTest

المؤلفون: Weisenberger, D J, Siegmund, K D, Campan, M, Young, J, Long, T I, Faasse, M A, Kang, G H, Widschwendter, M, Weener, D, Buchanan, D, Koh, H, Simms, S, Barker, M, Leggett, B, Levine, J, Kim, M J, French, A J, Thibodeau, S N, Jass, F, Haile, R, Laird, P W

المساهمون: Weisenberger, Daniel J, Siegmund, Kimberly D, Campan, Mihaela, Young, Joanne, Long, Tiffany I, Faasse, Mark A, Kang, Gyeong Hoon, Widschwendter, Martin, Weener, Deborah, Buchanan, Daniel, Koh, Hoey, Simms, Lisa, Barker, Melissa, Leggett, Barbara, Levine, Joan, Kim, Myungjin, Thibodeau, Stephen N, French, Amy J, Jass, Jeremy, Laird, Peter W, Haile, Robert

مصطلحات موضوعية: Colorectal Neoplasms/*genetics, DNA Repair/genetics, DNA, Neoplasm/chemistry/genetics, Epigenesis, Genetic, Gene Silencing, Genomic Instability, Humans, Microsatellite Repeats, Models, Phenotype, Promoter Regions, Proto-Oncogene Proteins B-raf/*genetics, CpG Islands, DNA Methylation, Mutation

العلاقة: Nat. Genet. 38(7), 787-793 (2006).; https://hdl.handle.net/10371/10052Test

الإتاحة: https://doi.org/10.1038/ng1834Test
https://hdl.handle.net/10371/10052Test

المؤلفون: Budzowska, M. (Magdalena), Jaspers, I. (Iris), Essers, J. (Jeroen), Waard, H. (Harm) de, Drunen, E. (Ellen) van, Hanada, K. (Katsuhiro), Beverloo, H.B. (Berna), Hendriks, R.W. (Rudi), Klein, J.E.M.M. (Annelies) de, Kanaar, R. (Roland), Hoeijmakers, J.H.J. (Jan), Maas, A. (Alex)

المصدر: EMBO Journal vol. 23 no. 17, pp. 3548-3558

مصطلحات موضوعية: Mutation, Amino Acid Sequence, Animals, Base Sequence, Cell Cycle Proteins/*genetics/metabolism, Cell Cycle/genetics, Cell Line, DNA Damage, DNA Repair/genetics, DNA-Binding Proteins, DNA/genetics, Female, Fetal Death/*genetics, Gamma Rays, Gene Targeting, Genes, Lethal, Gestational Age, Mice, Inbred C57BL, Knockout, Models, Biological, Molecular Sequence Data, Mutagens/toxicity, Pregnancy, Radiation Tolerance/genetics, Recombination, Genetic, Research Support

العلاقة: http://repub.eur.nl/pub/13479Test; urn:hdl:1765/13479

الإتاحة: https://doi.org/10.1038/sj.emboj.7600353Test
http://repub.eur.nl/pub/13479Test

المؤلفون: Baarends, W.M. (Willy), Wassenaar, E. (Evelyne), Hoogerbrugge, J.W. (Jos), Cappellen, W.A. (Gert) van, Roest, H.P. (Henk), Vreeburg, J.T.M. (Jan), Ooms, M.P. (Marja), Hoeijmakers, J.H.J. (Jan), Grootegoed, J.A. (Anton)

المصدر: Molecular and Cellular Biology

مصطلحات موضوعية: Crossing Over, Genetic, Meiosis, Ubiquitin-Conjugating Enzymes, Animals, Carrier Proteins, Cell Death/genetics, DNA Repair/genetics, Ligases/genetics/*metabolism, Male, Mice, Inbred C57BL, Knockout, Mutation, Neoplasm Proteins/genetics/metabolism, Nuclear Proteins, Prophase/*genetics, Research Support, Non-U.S. Gov't, Spermatocytes/physiology, Synaptonemal Complex/genetics/*ultrastructure, Telomere/genetics/metabolism, Testis/cytology/physiology, Ubiquitin/metabolism

وصف الملف: application/pdf

العلاقة: http://repub.eur.nl/pub/10083Test; urn:hdl:1765/10083

الإتاحة: http://repub.eur.nl/pub/10083Test