المؤلفون: Zhao, Chunlong, Chen, Deng, Suo, Feng-zhi, Setroikromo, Rita, Quax, Wim J., Dekker, Frank

المصدر: Zhao , C , Chen , D , Suo , F , Setroikromo , R , Quax , W J & Dekker , F 2023 , ' Discovery of highly potent HDAC8 PROTACs with anti-tumor activity ' , Bioorganic Chemistry , vol. 136 , 106546 . https://doi.org/10.1016/j.bioorg.2023.106546Test

مصطلحات موضوعية: Humans, Repressor Proteins, Proteolysis Targeting Chimera, Cell Line, Tumor, Histone Deacetylases/metabolism, Jurkat Cells, Proteolysis, Histone Deacetylase Inhibitors/pharmacology

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/3d9675c4-ed9f-42b6-a5ce-db018f138559Test

الإتاحة: https://doi.org/10.1016/j.bioorg.2023.106546Test
https://hdl.handle.net/11370/3d9675c4-ed9f-42b6-a5ce-db018f138559Test
https://research.rug.nl/en/publications/3d9675c4-ed9f-42b6-a5ce-db018f138559Test
https://pure.rug.nl/ws/files/643992592/1_s2.0_S0045206823002067_main.pdfTest

المؤلفون: Pu, Jingjing, Liu, Ting, Sharma, Amit, Schmidt-Wolf, Ingo G H

المصدر: BMC medical genomics 16(1), 295 (2023). doi:10.1186/s12920-023-01724-3

مصطلحات موضوعية: info:eu-repo/classification/ddc/610, Humans, Histone Deacetylases: genetics, Histone Deacetylases: metabolism, Histone Deacetylase 6, Histone Deacetylase Inhibitors: pharmacology, Histone Deacetylase Inhibitors: therapeutic use, MicroRNAs: genetics, Multiple Myeloma: drug therapy, Multiple Myeloma: genetics, Histone Deacetylases, Cancer, Epigenetics, Non-coding genome, Histone Deacetylase Inhibitors, MicroRNAs

جغرافية الموضوع: DE

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/pmid:37978516; info:eu-repo/semantics/altIdentifier/issn/1755-8794; https://pub.dzne.de/record/266012Test; https://pub.dzne.de/search?p=id:%22DZNE-2023-01086%22Test

الإتاحة: https://doi.org/10.1186/s12920-023-01724-3Test
https://pub.dzne.de/record/266012Test
https://pub.dzne.de/search?p=id:%22DZNE-2023-01086%22Test

المؤلفون: Andersen, Phillip Alexander Keller, Petrenko, Volodymyr, Rose, Peter Horskjær, Koomen, Melissa, Fischer, Nico, Ghiasi, Seyed Mojtaba, Dahlby, Tina, Dibner, Charna, Mandrup-Poulsen, Thomas

المصدر: ISSN: 1661-6596 ; International Journal of Molecular Sciences, vol. 22, no. 1 (2020) 83.

مصطلحات موضوعية: info:eu-repo/classification/ddc/612, info:eu-repo/classification/ddc/616, ARNTL Transcription Factors/genetics/metabolism, Animals, Cell Line, Tumor, Cells, Cultured, Circadian Rhythm, Female, HEK293 Cells, Histone Deacetylases/metabolism, Humans, Insulin/metabolism, Insulin-Secreting Cells/drug effects/metabolism, Interferon-gamma/metabolism/pharmacology, Male, Mice, Nitric Oxide/metabolism, Proteasome Endopeptidase Complex/metabolism, Reactive Oxygen Species/metabolism

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/33374803; https://archive-ouverte.unige.ch/unige:154823Test; unige:154823

الإتاحة: https://doi.org/10.3390/ijms22010083Test
https://archive-ouverte.unige.ch/unige:154823Test

المؤلفون: Ana Katušić-Bojanac, Milvija Plazibat, Marta Himelreich-Perić, Katarina Eck-Raković, Jure Krasić, Nino Sinčić, Gordana Jurić-Lekić, Davor Ježek, Floriana Bulić-Jakuš

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 16; Pages: 8861

مصطلحات موضوعية: Placenta, Histone Deacetylases, Catalysis, Inorganic Chemistry, Pregnancy, Animals, Humans, Physical and Theoretical Chemistry, valproate, HDACi, neural tissue, ectoplacental cone, embryo, Molecular Biology, Spectroscopy, Placenta / metabolism, Mammals, Valproic Acid / pharmacology, Valproic Acid, Organic Chemistry, Gastrulation, Mammals / metabolism, Acetylation, General Medicine, Histone Deacetylase Inhibitors / pharmacology, Computer Science Applications, Rats, Histone Deacetylase Inhibitors, Histone Deacetylases / metabolism, Female

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e94172e33185d6c105d2d22ab302ee8bTest

المؤلفون: Ronin, C, Costa, DM, Tavares, J, Faria, J, Ciesielski, F, Ciapetti, P, Smith, TK, MacDougall, J, Cordeiro-da-Silva, A, Pemberton, I

المساهمون: Instituto de Investigação e Inovação em Saúde

مصطلحات موضوعية: Binding Site, Crystallography, X-Ray, Drug Design, Group III Histone Deacetylases / chemistry, Group III Histone Deacetylases / metabolism, Humans, Leishmania infantum / metabolismo, Models, Molecular, Peptides / metabolism, Protein Binding, Protein Structure, Secondary, Protozoan Proteins / chemistry, Protozoan Proteins / metabolism

وصف الملف: application/pdf

العلاقة: info:eu-repo/grantAgreement/EC/FP7/602773/EU; PLoS ONE, vol.13(3):e0193602; https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0193602Test; https://hdl.handle.net/10216/127391Test

الإتاحة: https://doi.org/10.1371/journal.pone.0193602Test
https://hdl.handle.net/10216/127391Test

المساهمون: Others, Severance Hospital, Woo Sun Kwon, Sun Young Rha, Hei-Cheul Jeung, Tae Soo Kim, Hyun Cheol Chung, Kim, Tae Soo, Rha, Sun Young, Chung, Hyun Cheol, Jeung, Hei Cheul

مصطلحات موضوعية: Acetylation/drug effects, Amino Acid Substitution, Antineoplastic Agents, Phytogenic/pharmacology, Antineoplastic Combined Chemotherapy Protocols/pharmacology, BRCA2 Protein/genetics, BRCA2 Protein/metabolism, Breast Neoplasms/drug therapy, Breast Neoplasms/genetics, Breast Neoplasms/metabolism, Cell Line, Tumor, Cell Survival/drug effects, Drug Resistance, Neoplasm/drug effects, Female, Heterozygote, Histone Deacetylase Inhibitors/pharmacology, Histone Deacetylases/chemistry, Histone Deacetylases/metabolism, Humans, Mutation, Neoplasm Proteins/antagonists & inhibitors, Neoplasm Proteins/genetics, Neoplasm Proteins/metabolism, Paclitaxel/pharmacology, Polymorphism, Single Nucleotide, Protein-Serine-Threonine Kinases/genetics, Protein-Serine-Threonine Kinases/metabolism

العلاقة: BIOCHEMICAL PHARMACOLOGY; J00283; OAK-2017-03170; https://ir.ymlib.yonsei.ac.kr/handle/22282913/160319Test; https://www.sciencedirect.com/science/article/pii/S0006295217302320Test; T201702086; BIOCHEMICAL PHARMACOLOGY, Vol.138 : 163-173, 2017

الإتاحة: https://doi.org/10.1016/j.bcp.2017.04.015Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/160319Test
https://www.sciencedirect.com/science/article/pii/S0006295217302320Test

المساهمون: College of Medicine, Dept. of Surgery, Hyun-Wook Ryu, Dong-Hee Shin, Dong Hoon Lee, Junjeong Choi, Gyoonhee Han, Kang Young Lee, So Hee Kwon, Lee, Kang Young

مصطلحات موضوعية: Apoptosis, HSP90 Heat-Shock Proteins/metabolism, Histone Deacetylase Inhibitors/pharmacology, Histone Deacetylase Inhibitors/therapeutic use, Histone Deacetylases/metabolism, Humans, Lysine, Tumor Suppressor Protein p53/metabolism, HDAC6-selective inhibitor, Histone deacetylase 6, Hsp90, p53

العلاقة: CANCER LETTERS; J00448; OAK-2017-00833; https://ir.ymlib.yonsei.ac.kr/handle/22282913/154678Test; http://www.sciencedirect.com/science/article/pii/S0304383517300757Test; T201700423; CANCER LETTERS, Vol.391 : 162-171, 2017

الإتاحة: https://doi.org/10.1016/j.canlet.2017.01.033Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/154678Test
http://www.sciencedirect.com/science/article/pii/S0304383517300757Test

المساهمون: College of Medicine, Dept. of Internal Medicine, Jin-Hua Chi, Geom Seog Seo, Jae Hee Cheon, Sung Hee Lee, Cheon, Jae Hee

مصطلحات موضوعية: Acetylation/drug effects, Chalcones/pharmacology, Enzyme Activation/drug effects, HMGB1 Protein/secretion, HT29 Cells, Histone Deacetylases/metabolism, Humans, Inflammation Mediators/metabolism, Intestinal Mucosa/drug effects, Intestinal Mucosa/pathology, Intestinal Mucosa/secretion, NF-kappa B/metabolism, Tumor Necrosis Factor-alpha/pharmacology, High-mobility group box 1, Histone deacetylase, Inflammatory bowel disease, Intestinal epithelial cell, Isoliquiritigenin, Isoliquiritigenin (PubChem CID: 638278), Scriptaid (PubChem CID: 5186)

العلاقة: EUROPEAN JOURNAL OF PHARMACOLOGY; J00842; OAK-2017-01275; https://ir.ymlib.yonsei.ac.kr/handle/22282913/154547Test; http://www.sciencedirect.com/science/article/pii/S001429991630810XTest; T201700685; EUROPEAN JOURNAL OF PHARMACOLOGY, Vol.796 : 101-109, 2017

الإتاحة: https://doi.org/10.1016/j.ejphar.2016.12.026Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/154547Test
http://www.sciencedirect.com/science/article/pii/S001429991630810XTest

المساهمون: College of Medicine, Dept. of Biochemistry & Molecular Biology, Mi-Hyeon Jeong, Hyeonseok Ko, Hyelin Jeon, Gi-Jun Sung, Soo-Yeon Park, Woo Jin Jun, Yoo-Hyun Lee, Jeongmin Lee, Sang-wook Lee, Ho-Geun Yoon, Kyung-Chul Choi, Park, Soo Yeon, Yoon, Ho Geun

مصطلحات موضوعية: Acetylation, Anthocyanins/pharmacology, Antineoplastic Agents, Phytogenic/pharmacology, Apoptosis, Caspase 3/metabolism, Caspase 7/metabolism, Caspase 8/metabolism, Cell Line, Tumor, Cell Survival, Epigenesis, Genetic, Gene Expression Regulation, Enzymologic, Neoplastic, Histone Deacetylases/genetics, Histone Deacetylases/metabolism, Humans, Male, Plant Extracts/pharmacology, Prostatic Neoplasms/drug therapy, Prostatic Neoplasms/genetics, Prostatic Neoplasms/metabolism, RNA Interference, Tumor Suppressor Protein p53/genetics, Tumor Suppressor Protein p53/metabolism, HDAC3, apoptosis, delphinidin

العلاقة: ONCOTARGET; J02421; OAK-2016-05304; https://ir.ymlib.yonsei.ac.kr/handle/22282913/152049Test; T201603562; ONCOTARGET , Vol.7(35) : 56767-56780, 2016; 46829

الإتاحة: https://doi.org/10.18632/oncotarget.10790Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/152049Test

المؤلفون: Cironi, L., Petricevic, T., Fernandes Vieira, V., Provero, P., Fusco, C., Cornaz, S., Fregni, G., Letovanec, I., Aguet, M., Stamenkovic, I.

المصدر: Scientific reports, vol. 6, pp. 22113

مصطلحات موضوعية: Animals, Axin Protein/genetics, Axin Protein/metabolism, Blotting, Western, Cell Line, Tumor, Gene Expression Profiling/methods, Histone Deacetylases/genetics, Histone Deacetylases/metabolism, Humans, Mice, Microscopy, Confocal, Oncogene Proteins, Fusion/genetics, Fusion/metabolism, RNA Interference, Repressor Proteins/genetics, Repressor Proteins/metabolism, Reverse Transcriptase Polymerase Chain Reaction, Sarcoma, Synovial/genetics, Synovial/metabolism, Synovial/pathology, TCF Transcription Factors/genetics, TCF Transcription Factors/metabolism, Transcription Factors/genetics, Transcription Factors/metabolism, Wnt Signaling Pathway/genetics

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/26905812; info:eu-repo/semantics/altIdentifier/eissn/2045-2322; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_66B69F702FDC3; https://serval.unil.ch/notice/serval:BIB_66B69F702FDCTest; urn:issn:2045-2322; https://serval.unil.ch/resource/serval:BIB_66B69F702FDC.P001/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_66B69F702FDC3Test

الإتاحة: https://doi.org/10.1038/srep22113Test
https://serval.unil.ch/notice/serval:BIB_66B69F702FDCTest
https://serval.unil.ch/resource/serval:BIB_66B69F702FDC.P001/REF.pdfTest
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_66B69F702FDC3Test