المؤلفون: van Dessel, Lisanne F., van Riet, Job, Smits, Minke, Zhu, Yanyun, Hamberg, Paul, van der Heijden, Michiel S., Bergman, Andries M., van Oort, Inge M., de Wit, Ronald, Voest, Emile E., Steeghs, Neeltje, Yamaguchi, Takafumi N., Livingstone, Julie, Boutros, Paul C., Martens, John W.M., Sleijfer, Stefan, Cuppen, Edwin, Zwart, Wilbert, van de Werken, Harmen J.G., Mehra, Niven, Lolkema, Martijn P.

المصدر: van Dessel , L F , van Riet , J , Smits , M , Zhu , Y , Hamberg , P , van der Heijden , M S , Bergman , A M , van Oort , I M , de Wit , R , Voest , E E , Steeghs , N , Yamaguchi , T N , Livingstone , J , Boutros , P C , Martens , J W M , Sleijfer , S , Cuppen , E , Zwart , W , van de Werken , H J G , Mehra , N & ....

مصطلحات موضوعية: BRCA2 Protein/genetics, Bone Neoplasms/genetics, Chromatin Immunoprecipitation Sequencing, Cyclin-Dependent Kinases/genetics, DNA Copy Number Variations, Enhancer Elements, Genetic/genetics, Genotype, Humans, Liver Neoplasms/genetics, Lymph Nodes, Male, Microsatellite Instability, Neoplasm Metastasis, Oncogene Proteins, Fusion/genetics, Prostatic Neoplasms/genetics, Prostatic Neoplasms, Castration-Resistant/classification, Receptors, Androgen/genetics, Recombinational DNA Repair/genetics, Soft Tissue Neoplasms/genetics, Whole Genome Sequencing, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

العلاقة: https://research.tue.nl/en/publications/a16e37b4-1ba5-4d6e-894f-78b4b730cdbfTest

الإتاحة: https://doi.org/10.1038/s41467-019-13084-7Test
https://research.tue.nl/en/publications/a16e37b4-1ba5-4d6e-894f-78b4b730cdbfTest
http://www.scopus.com/inward/record.url?scp=85075391947&partnerID=8YFLogxKTest

المؤلفون: Waddell, Nicola, Pajic, Marina, Patch, Ann-Marie, Chang, David K, Kassahn, Karin S, Bailey, Peter, Johns, Amber L, Miller, David, Nones, Katia, Quek, Kelly, Quinn, Michael C J, Robertson, Alan J, Fadlullah, Muhammad Z H, Bruxner, Tim J C, Christ, Angelika N, Harliwong, Ivon, Idrisoglu, Senel, Manning, Suzanne, Nourse, Craig, Nourbakhsh, Ehsan, Wani, Shivangi, Wilson, Peter J, Markham, Emma, Cloonan, Nicole, Anderson, Matthew J, Fink, J Lynn, Holmes, Oliver, Kazakoff, Stephen H, Leonard, Conrad, Newell, Felicity, Poudel, Barsha, Song, Sarah, Taylor, Darrin, Waddell, Nick, Wood, Scott, Xu, Qinying, Wu, Jianmin, Pinese, Mark, Cowley, Mark J, Lee, Hong C, Jones, Marc D, Nagrial, Adnan M, Humphris, Jeremy, Chantrill, Lorraine A, Chin, Venessa, Steinmann, Angela M, Mawson, Amanda, Humphrey, Emily S, Colvin, Emily K, Chou, Angela, Scarlett, Christopher J, Pinho, Andreia V, Giry-Laterriere, Marc, Rooman, Ilse, Samra, Jaswinder S, Kench, James G, Pettitt, Jessica A, Merrett, Neil D, Toon, Christopher, Epari, Krishna, Nguyen, Nam Q, Barbour, Andrew, Zeps, Nikolajs, Jamieson, Nigel B, Graham, Janet S, NICLOU, Simone P., Bjerkvig, Rolf, Grützmann, Robert, Aust, Daniela, Hruban, Ralph H, Maitra, Anirban, Iacobuzio-Donahue, Christine A, Wolfgang, Christopher L, Morgan, Richard A, Lawlor, Rita T, Corbo, Vincenzo, Bassi, Claudio, Falconi, Massimo, Zamboni, Giuseppe, Tortora, Giampaolo, Tempero, Margaret A, Australian Pancreatic Cancer Genome, Gill, Anthony J, Eshleman, James R, Pilarsky, Christian, Scarpa, Aldo, Musgrove, Elizabeth A, Pearson, John V, Biankin, Andrew V, Grimmond, Sean M

المساهمون: Biankin, Andrew V, Johns, Amber L, Mawson, Amanda, Chang, David K, Scarlett, Christopher J, Brancato, Mary-Anne L, Rowe, Sarah J, Simpson, Skye H, Martyn-Smith, Mona, Thomas, Michelle T, Chantrill, Lorraine A, Chin, Venessa T, Chou, Angela, Cowley, Mark J, Humphris, Jeremy L, Jones, Marc D, Mead, R Scott, Nagrial, Adnan M, Pajic, Marina, Pettit, Jessica, Pinese, Mark, Rooman, Ilse, Wu, Jianmin, Tao, Jiang, DiPietro, Renee, Watson, Clare, Steinmann, Angela, Ching Lee, Hong, Wong, Rachel, Pinho, Andreia V, Giry-Laterriere, Marc, Daly, Roger J, Musgrove, Elizabeth A, Sutherland, Robert L, Grimmond, Sean M, Waddell, Nicola, Kassahn, Karin S, Miller, David K, Wilson, Peter J, Patch, Ann-Marie, Song, Sarah, Harliwong, Ivon, Idrisoglu, Senel, Nourse, Craig, Nourbakhsh, Ehsan, Manning, Suzanne, Wani, Shivangi, Gongora, Milena, Anderson, Matthew, Holmes, Oliver, Leonard, Conrad, Taylor, Darrin, Wood, Scott, Xu, Christina, Nones, Katia, Fink, J Lynn, Christ, Angelika, Bruxner, Tim, Cloonan, Nicole, Newell, Felicity, Pearson, John V, Bailey, Peter, Quinn, Michael, Nagaraj, Shivashankar, Kazakoff, Stephen, Waddell, Nick, Krisnan, Keerthana, Quek, Kelly, Wood, David, Fadlullah, Muhammad Z H, Samra, Jaswinder S, Gill, Anthony J, Pavlakis, Nick, Guminski, Alex, Toon, Christopher, Asghari, Ray, Merrett, Neil D, Pavey, Darren, Das, Amitabha, Cosman, Peter H, Ismail, Kasim, O'Connnor, Chelsie, Lam, Vincent W, McLeod, Duncan, Pleass, Henry C, Richardson, Arthur, James, Virginia, Kench, James G, Cooper, Caroline L, Joseph, David, Sandroussi, Charbel, Crawford, Michael, Gallagher, James, Texler, Michael, Forest, Cindy, Laycock, Andrew, Epari, Krishna P, Ballal, Mo, Fletcher, David R, Mukhedkar, Sanjay

المصدر: Nature, 518 (7540), 495-501 (2015-02-26)

مصطلحات موضوعية: Genetic Markers, Poly(ADP-ribose) Polymerase Inhibitors, 49DFR088MY (Platinum), Adenocarcinoma/drug therapy/genetics, Animals, Carcinoma, Pancreatic Ductal/drug therapy/genetics, DNA Mutational Analysis, DNA Repair/genetics, Female, Genes, BRCA1, BRCA2, Genetic Markers/genetics, Genome, Human/genetics, Genomic Instability/genetics, Genomics, Genotype, Humans, Mice, Mutation/genetics, Pancreatic Neoplasms/classification/drug therapy/genetics, Platinum/pharmacology, Point Mutation/genetics, Xenograft Model Antitumor Assays, Human health sciences, Oncology, Sciences de la santé humaine, Oncologie

العلاقة: urn:issn:0028-0836; urn:issn:1476-4687; https://orbilu.uni.lu/handle/10993/60218Test; info:hdl:10993/60218; https://orbilu.uni.lu/bitstream/10993/60218/1/nature14169.pdfTest; scopus-id:2-s2.0-84924056345; info:pmid:25719666

الإتاحة: https://doi.org/10.1038/nature14169Test
https://orbilu.uni.lu/handle/10993/60218Test
https://orbilu.uni.lu/bitstream/10993/60218/1/nature14169.pdfTest

المصدر: 2014 , ' DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers ' , PLoS Genetics , vol. 10 , no. 4 , pp. e1004256 . https://doi.org/10.1371/journal.pgen.1004256Test

مصطلحات موضوعية: Adolescent, Adult, Aged, 80 and over, BRCA1 Protein/genetics, BRCA2 Protein/genetics, Breast Neoplasms/genetics, DNA Glycosylases/genetics, DNA Repair/genetics, Female, Genetic Predisposition to Disease, Genotype, Humans, Middle Aged, Ovarian Neoplasms/genetics, Polymorphism, Single Nucleotide/genetics, Risk

الإتاحة: https://doi.org/10.1371/journal.pgen.1004256Test
https://kclpure.kcl.ac.uk/portal/en/publications/7fcb7fce-99e7-4484-9fa8-aa6c5f419ff8Test

المؤلفون: Huang, Wen-Yi, Berndt, Sonja I., Kang, Daehee, Chatterjee, Nilanjan, Chanock, Stephen J., Yeager, Meredith, Welch, Robert, Bresalier, Rober S., Weissfeld, Joel L., Hayes, Richard B.

المساهمون: 강대희

مصطلحات موضوعية: Adenoma/*genetics, Aged, Alleles, Case-Control Studies, Colorectal Neoplasms/*genetics, DNA Helicases/genetics, DNA Repair/*genetics, DNA-Binding Proteins/*genetics, Female, Genotype, Humans, Linkage Disequilibrium, Logistic Models, Male, Middle Aged, Multivariate Analysis, Risk Factors, Smoking/adverse effects/*genetics, Polymorphism, Single Nucleotide

العلاقة: Cancer Epidemiol Biomarkers Prev. 2006 Feb;15(2):306-11.; 1055-9965 (Print); http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16492920Test; https://hdl.handle.net/10371/28303Test

الإتاحة: https://doi.org/10.1158/1055-9965.EPI-05-0751Test
https://hdl.handle.net/10371/28303Test
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16492920Test

المؤلفون: Lee, Kyoung-Mu, Choi, Ji-Yeob, Kang, Changwon, Kang, Changsoo Paul, Park, Sue Kyung, Cho, Hyunmi, Cho, Dae-Yeon, Yoo, Keun-Young, Noh, Dong-Young, Ahn, Sei-Hyun, Park, Chung-Gyu, Wei, Qingyi, Kang, Daehee

المساهمون: 이경무, 최지엽, 강창원, 강창수, 박수경, 조현미, 조대연, 유근영, 노동영, 안세현, 박충규, 강대희

مصطلحات موضوعية: Adaptor Proteins, Signal Transducing, Adult, Breast Neoplasms/genetics/metabolism/*pathology, Carrier Proteins, Case-Control Studies, DNA Repair/*genetics, DNA-Binding Proteins/genetics, Endonucleases/genetics, Female, Genotype, Humans, Immunohistochemistry, Middle Aged, Neoplasm Proteins/genetics, Nuclear Proteins/genetics, Rad52 DNA Repair and Recombination Protein, Receptors, Estrogen/*analysis, Progesterone/*analysis, Risk Factors, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization, Polymorphism, Genetic

العلاقة: Clin Cancer Res. 2005 Jun 15;11(12):4620-6.; 1078-0432 (Print); http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15958648Test; https://hdl.handle.net/10371/27896Test

الإتاحة: https://doi.org/10.1158/1078-0432.CCR-04-2534Test
https://hdl.handle.net/10371/27896Test
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15958648Test

المؤلفون: Martijn P. Lolkema, Harmen J.G. van de Werken, Paul C. Boutros, Andries M. Bergman, Takafumi N. Yamaguchi, Yanyun Zhu, Lisanne F. van Dessel, Job van Riet, Niven Mehra, Wilbert Zwart, Julie Livingstone, Neeltje Steeghs, Stefan Sleijfer, Ronald de Wit, Michiel S. van der Heijden, Minke Smits, Edwin Cuppen, Paul Hamberg, Emile E. Voest, John W.M. Martens, Inge M. van Oort

المساهمون: Graduate School, Chemical Biology, Medical Oncology, Urology

المصدر: Nature communications, 10(1):5251. Nature Publishing Group
Nature Communications, 10
Nature Communications, 10(1):5251. Nature Publishing Group
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications, 10(1). Nature Publishing Group
Nature Communications
Nature communications, vol 10, iss 1
Nature Communications, 10:5251. Nature Publishing Group

مصطلحات موضوعية: Male, 0301 basic medicine, Oncogene Proteins, Fusion, Chemistry(all), Recombinational DNA Repair/genetics, General Physics and Astronomy, Soft Tissue Neoplasms, Castration-Resistant, SDG 3 – Goede gezondheid en welzijn, Biochemistry, Androgen, Prostate cancer, 0302 clinical medicine, Prostate, Genetics research, Receptors, Genotype, Neoplasm Metastasis, lcsh:Science, Cancer, Oncogene Proteins, Multidisciplinary, Prostatic Neoplasms/genetics, Prostate Cancer, Liver Neoplasms, Fusion/genetics, BRCA2 Protein/genetics, Cyclin-Dependent Kinases, Cyclin-Dependent Kinases/genetics, Receptors, Androgen/genetics, 3. Good health, Prostatic Neoplasms, Castration-Resistant, Enhancer Elements, Genetic, medicine.anatomical_structure, Receptors, Androgen, 030220 oncology & carcinogenesis, Urological cancers Radboud Institute for Health Sciences [Radboudumc 15], Chromatin Immunoprecipitation Sequencing, Microsatellite Instability, Tandem exon duplication, Castration-Resistant/classification, Biotechnology, Urologic Diseases, Enhancer Elements, DNA Copy Number Variations, Science, Bone Neoplasms, Computational biology, Physics and Astronomy(all), Biology, Castration resistant, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, All institutes and research themes of the Radboud University Medical Center, Genetic, SDG 3 - Good Health and Well-being, Urological cancers Radboud Institute for Molecular Life Sciences [Radboudumc 15], Genetics, Journal Article, medicine, Humans, Fusion, Liver Neoplasms/genetics, Genetic/genetics, BRCA2 Protein, Whole genome sequencing, Whole Genome Sequencing, Biochemistry, Genetics and Molecular Biology(all), Human Genome, Enhancer Elements, Genetic/genetics, Androgen/genetics, Recombinational DNA Repair, Prostatic Neoplasms, Microsatellite instability, Prostatic Neoplasms, Castration-Resistant/classification, Bone Neoplasms/genetics, General Chemistry, Soft Tissue Neoplasms/genetics, medicine.disease, Good Health and Well Being, 030104 developmental biology, Tumor progression, Oncogene Proteins, Fusion/genetics, lcsh:Q, Lymph Nodes, Genetics and Molecular Biology(all)

وصف الملف: application/pdf; image/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2882275e8ceb9ccb244ebae17d027bd1Test
https://pure.amc.nl/en/publications/the-genomic-landscape-of-metastatic-castrationresistant-prostate-cancers-reveals-multiple-distinct-genotypes-with-potential-clinical-impactTest(1c43a7d4-1537-4df6-99fc-d5fc23d2db5a).html

المؤلفون: Wagner, A. (Anja), Krimpen, C. (Cees) van, Morreau, H. (Hans), Hofstra, R.M.W. (Robert), Tops, C. (Carli), Cornelisse, C.J. (Cees), Zwinderman, A.H. (Ailko), Bik, E.C. (Elsa), Brocker-Vriends, A.H., Fodde, R. (Riccardo), Breuning, M.H. (Martijn), Meer, C.A. (Conny) van der, Vasen, H.F. (Hans), Niermeijer, M.F. (Martinus), Lindhout, D. (Dick), Hendriks, Y., Meijers-Heijboer, E.J. (Hanne), Wijnen, J.T. (Juul), Leeuw, W.J. de

المصدر: Journal of Medical Genetics

مصطلحات موضوعية: Adult, Age of Onset, Aged, 80 and over, Base Pair Mismatch/genetics, Carcinoma, Transitional Cell/epidemiology/genetics/pathology, Colorectal Neoplasms, Hereditary Nonpolyposis/epidemiology/*genetics/pathology, DNA Mutational Analysis, DNA Repair/genetics, DNA-Binding Proteins/*genetics, Diagnosis, Differential, Endometrial Neoplasms/epidemiology/genetics/pathology, Female, Frameshift Mutation/genetics, Genetic Predisposition to Disease/genetics, Genotype, Germ-Line Mutation/*genetics, Humans, Immunohistochemistry, Male, Microsatellite Repeats/genetics, Middle aged, Netherlands, Pedigree, Penetrance, Urologic Neoplasms/epidemiology/genetics/pathology

وصف الملف: application/pdf

العلاقة: http://repub.eur.nl/pub/9633Test; urn:hdl:1765/9633

الإتاحة: https://doi.org/10.1136/jmg.38.5.318Test
http://repub.eur.nl/pub/9633Test

المؤلفون: Belkum, A.F. (Alex) van, Scherer, S., Alphen, L. (Loek) van, Verbrugh, H.A. (Henri)

المصدر: Microbiology and Molecular Biology Reviews

مصطلحات موضوعية: Adhesins, Bacterial/genetics, Animals, Bacteria/pathogenicity, Base Sequence/genetics, DNA Repair/genetics, DNA, Bacterial/*genetics, Protozoan/genetics, Gene Expression Regulation, Bacterial, Genome, Protozoan, Genotype, Repetitive Sequences, Nucleic Acid/*genetics

وصف الملف: application/pdf

العلاقة: http://repub.eur.nl/pub/8835Test; urn:hdl:1765/8835

الإتاحة: http://repub.eur.nl/pub/8835Test

المؤلفون: Engelward, B.P. (Bevin), Weeda, G. (Geert), Wyatt, M.D., Broekhof, J.L.M. (Jose'), Wit, J. (Jan) de, Donker, I. (Ingrid), Allan, J.M. (James), Gold, B. (Bert), Hoeijmakers, J.H.J. (Jan), Samson, L.D. (Leona)

المصدر: Proceedings of the National Academy of Sciences of the United States of America vol. 94 no. 24, pp. 13087-13092

مصطلحات موضوعية: DNA Glycosylases, 0 (Alkylating Agents), 0 (DNA, Complementary), Alkylating Agents/pharmacology, Animals, Crosses, Genetic, DNA Repair/*genetics, DNA, Complementary, EC 3.2.2.- (3-methyladenine-DNA glycosylase), EC 3.2.2.- (DNA Glycosylases), EC 3.2.2.- (N-Glycosyl Hydrolases), Female, Genotype, Male, Mice, Inbred C57BL, Knockout, N-Glycosyl Hydrolases/genetics/*metabolism, Support, Non-U.S. Gov't, U.S. Gov't, P.H.S

وصف الملف: application/pdf

العلاقة: http://repub.eur.nl/pub/3129Test; urn:hdl:1765/3129

الإتاحة: http://repub.eur.nl/pub/3129Test

المصدر: 2016 , ' Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array ' , British journal of cancer , vol. 114 , no. 8 , pp. 945-52 . https://doi.org/10.1038/bjc.2016.50Test

مصطلحات موضوعية: BRCA1 Protein/genetics, Case-Control Studies, Cell Cycle Proteins/genetics, DNA/genetics, DNA Repair/genetics, DNA Repair Enzymes/genetics, DNA-Binding Proteins/genetics, Genes, BRCA2/physiology, Genetic Predisposition to Disease/genetics, Genome-Wide Association Study/methods, Genotype, Germ-Line Mutation/genetics, Humans, Male, Polymorphism, Single Nucleotide/genetics, Prospective Studies, Prostatic Neoplasms/genetics, Risk

الإتاحة: https://doi.org/10.1038/bjc.2016.50Test
https://kclpure.kcl.ac.uk/portal/en/publications/1ead523c-a333-4c1c-9fde-0dad2568c960Test