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المؤلفون: Helen Lenthall, Isabelle Meyts, Robert Brink, Kathryn Payne, Christoph Burkhart, Kaan Boztug, Wei Shi, Elise French, Melanie Wong, Lynn M. Corcoran, Gulbu Uzel, William A. Sewell, Michael O'Sullivan, Lucinda J. Berglund, Danielle T. Avery, Alisa Kane, David Zahra, Paul Gray, Danyal Butt, Tri Giang Phan, Anthony Lau, Sharon Choo, Stuart G. Tangye, Henry Brigden, Peter Hsu, Elissa K. Deenick, Jana R. Hermes, Theresa Cole, Tina Nguyen, Michael Elliott, Cindy S. Ma, Julia Bier, Steven M. Holland, Akira Nguyen
المصدر: The Journal of Experimental Medicine
مصطلحات موضوعية: 0301 basic medicine, Cellular differentiation, Antibody Affinity, PI3 KINASE, Research & Experimental Medicine, PHOSPHOINOSITIDE 3-KINASE, medicine.disease_cause, CLASS-SWITCH RECOMBINATION, Mice, Phosphatidylinositol 3-Kinases, HUMAN IMMUNODEFICIENCY, SECRETING CELLS, Immunology and Allergy, Child, Research Articles, B-Lymphocytes, Mutation, biology, Cell Differentiation, Cytidine deaminase, ANTIBODY-PRODUCTION, 3. Good health, Cell biology, Phenotype, medicine.anatomical_structure, ANTIGEN AFFINITY, Medicine, Research & Experimental, Gain of Function Mutation, Models, Animal, PHOSPHATIDYLINOSITOL 3-KINASE, Antibody, Life Sciences & Biomedicine, Signal Transduction, Class I Phosphatidylinositol 3-Kinases, Plasma Cells, Immunology, Immunoglobulins, Bone Marrow Cells, Article, 03 medical and health sciences, Germline mutation, Immune system, medicine, 3-KINASE DELTA SYNDROME, Animals, Humans, Germ-Line Mutation, B cell, Cell Proliferation, P85-ALPHA SUBUNIT, Science & Technology, Interleukins, biochemical phenomena, metabolism, and nutrition, Immunoglobulin Class Switching, 030104 developmental biology, Immunoglobulin class switching, biology.protein
وصف الملف: Print-Electronic
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb0e6265bfc33cb2d8fc21980955e4a9Test
https://doi.org/10.1084/jem.20180010Test -
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المؤلفون: Danielle T. Avery, Rita Beier, Annaliesse Blincoe, Rubén Martínez-Barricarte, David A. Fulcher, Jamila El Baghdadi, Aydan Ikinciogullari, Sara Sebnem Kilic, Yoshiyuki Minegishi, Geetha Rao, Capucine Picard, Melanie Wong, Kathryn Payne, Michael Stormon, Polina Stepensky, Gulbu Uzel, Paul Gray, Stephen Adelstein, Martyn A. French, Masao Kobayashi, Matthew C. Cook, Jean-Laurent Casanova, Klaus Warnatz, Stuart G. Tangye, Bodo Grimbacher, Aziz Bousfiha, Stéphanie Boisson-Dupuis, Natalie Wong, Patrick O’Young, Tri Giang Phan, Akira Nguyen, James Torpy, Michael Elliott, Cindy S. Ma, John B. Ziegler, Steven M. Holland, Peter Hsu, Elissa K. Deenick, Satoshi Okada, Jacinta Bustamante, Sophie Hambleton, Dianne E. Campbell, Anne Puel, Peter D. Arkwright, Kaan Boztug, Nic Robertson
المساهمون: Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı., Kılıç, Sara Şebnem, AAH-1658-2021
المصدر: The Journal of Experimental Medicine
Ma, C S, Wong, N, Rao, G, Nguyen, A, Avery, D T, Payne, K, Torpy, J, O'Young, P, Deenick, E, Bustamante, J, Puel, A, Okada, S, Kobayashi, M, Martinez-Barricarte, R, Elliott, M, Kilic, S S, Baghdadi, J E, Minegishi, Y, Bousfiha, A, Robertson, N, Hambleton, S, Arkwright, P, French, M, Blincoe, A K, Hsu, P, Campbell, D E, Stormon, M O, Wong, M, Adelstein, S, Fulcher, D A, Cook, M C, Stepensky, P, Boztug, K, Beier, R, Ikincioğullari, A, Ziegler, J B, Gray, P, Picard, C, Boisson-Dupuis, S, Phan, T G, Grimbacher, B, Warnatz, K, Holland, S M, Uzel, G, Casanova, J L & Tangye, S G 2016, ' Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4 + T cells into distinct effector subsets ', Journal of Experimental Medicine, vol. 213, no. 8, pp. 1589-1608 . https://doi.org/10.1084/jem.20151467Testمصطلحات موضوعية: Male, 0301 basic medicine, Interleukin 12 receptor beta1, STAT6 protein, Cellular differentiation, Immune deficiency, Medizin, Follicular-helper-cells, STAT1 gene, Ectodermal dysplasia, medicine.disease_cause, STAT1 protein, human, Gene, Essential modulator mutation, Differentiation antigen, Chronic mucocutaneous candidiasis, Interleukin 10, Hyper-ige syndrome, Icos deficiency, STAT4 protein, Gain of function mutation, Immunology and Allergy, Research Articles, Priority journal, Th17 cell, Mutation, Th1 cell, Effector, Cell Differentiation, Interleukin-10, 3. Good health, Cell biology, Lymphocyte differentiation, STAT1 Transcription Factor, medicine.anatomical_structure, Intracellular signaling, Effector cell, Female, BCL6 expression, Signal transduction, CD4 antigen, Protein kinase TYK2, Human, STAT3 Transcription Factor, Cell subpopulation, T cell, IL10 protein, mouse, Immunology, Helper Cell, Germinal Center, Tfh Cell, Biology, Gamma interferon receptor, STAT3 gene, Article, Common variable immunodeficiency, Antibody-responses, Immunomodulation, 03 medical and health sciences, Protein phosphorylation, Th2 Cells, Immune system, STAT3 protein, Antigen, STAT1 protein, Genetics, medicine, Humans, Th0 cell, Medicine, research & experimental, Cytokine release, Gamma interferon, Infection sensitivity, L kappa B kinase gamma, CD4+ T lymphocyte, Immunoregulation, In vitro study, Th1 Cells, Interleukin 21 receptor, Antigens, Differentiation, Humoral immunity, Interleukin 21, Th2 cell, 030104 developmental biology, Human cell, Th17 Cells, Cytology, IL-10 production, Controlled study
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee2b2bc49c951ae46185f318cb05abbTest
http://repo.lib.tokushima-u.ac.jp/115511Test -
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المؤلفون: Fabienne Mackay, Danielle T. Avery, Kristy O'Donnell, Simona Infantino, Stuart G. Tangye, Vanessa L. Bryant, Gabrielle T. Belz, Michael Elliott, David M. Tarlinton, Amanda Light, Stéphane Richard
المصدر: Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)مصطلحات موضوعية: 0301 basic medicine, Cell signaling, Protein-Arginine N-Methyltransferases, Arginine, Cellular differentiation, Science, B-cell receptor, General Physics and Astronomy, Biology, Lymphocyte Activation, Methylation, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, medicine, Animals, Humans, lcsh:Science, B cell, B-Lymphocytes, Multidisciplinary, Germinal center, Cell Differentiation, General Chemistry, 3. Good health, Cell biology, Immunity, Humoral, Repressor Proteins, 030104 developmental biology, medicine.anatomical_structure, Biochemistry, 030220 oncology & carcinogenesis, lcsh:Q, Signal transduction, Protein Processing, Post-Translational
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea770da252488a40c3e6392d28050717Test
http://europepmc.org/articles/PMC5638811Test -
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المؤلفون: Cindy S. Ma, Christoph Klein, Anna Chan, Stéphanie Boisson-Dupuis, Diana Averbuch, Megan L. Ives, Stephen Adelstein, Jean-Laurent Casanova, David A. Fulcher, Dan Engelhard, Peter D. Arkwright, Anne Durandy, Gulbu Uzel, Jane Peake, Masao Kobayashi, Matthew C. Cook, Sharon Choo, Stuart G. Tangye, Danielle T. Avery, Jennifer Stoddard, Martyn A. French, Steven M. Holland, Lucinda J. Berglund, Elissa K. Deenick, Jacinta Bustamante, Melanie Wong, Miyuki Tsumura, Capucine Picard, Joanne Smart, Joachim Roesler, Leen Moens
المصدر: The Journal of Experimental Medicine
مصطلحات موضوعية: STAT3 Transcription Factor, Cellular differentiation, Immunology, Naive B cell, Plasma Cells, Immunoglobulin G, Atacicept, Article, 03 medical and health sciences, 0302 clinical medicine, Antigen, medicine, STAT5 Transcription Factor, Immunology and Allergy, Humans, Cell Lineage, Memory B cell, 030304 developmental biology, 0303 health sciences, B-Lymphocytes, CD40, biology, Interleukins, Interleukin-21 Receptor alpha Subunit, Cell Differentiation, medicine.disease, 3. Good health, Cell biology, Interleukin-10, Tumor Necrosis Factor Receptor Superfamily, Member 7, B-1 cell, STAT1 Transcription Factor, Mutation, biology.protein, Immunologic Memory, 030215 immunology, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c7412c58cb8ae777d42a735e4972ddTest
http://europepmc.org/articles/PMC3832925Test -
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المؤلفون: Jane Peake, Danielle T. Avery, Umamainthan Palendira, Martyn A. French, Robert Brink, Klaus Magdorf, Santi Suryani, Jean-Laurent Casanova, Karl Bleasel, Sami Al-Hajjar, D. Sean Riminton, Joachim Roesler, Gary Y. Chew, Nicholas Simpson, Cecile King, Dan Engelhard, Cindy S. Ma, Matthew C. Cook, Stuart G. Tangye, Tyani D. Chan, Melanie Wong, Stéphanie Boisson-Dupuis, Elissa K. Deenick, Jacinta Bustamante, Peter D. Arkwright, David A. Fulcher, Saleh Al-Muhsen, Sharon Choo, Pravin Hissaria
المساهمون: Faculty of Science and Engineering
المصدر: The Journal of Experimental Medicine
Journal of Experimental Medicine, 207(1), 155-171. ROCKEFELLER UNIV PRESSمصطلحات موضوعية: STAT3 Transcription Factor, Time Factors, Cellular differentiation, Plasma Cells, Immunology, B-cell receptor, Naive B cell, Immunoglobulins, Biology, Immunoglobulin secretion, Article, FOLLICULAR-HELPER-CELLS, HYPERIMMUNOGLOBULIN-E, SECRETING CELLS, COMMON GAMMA-CHAIN, medicine, Humans, Immunology and Allergy, Antigens, Memory B cell, JOBS SYNDROME, B cell, Common gamma chain, STAPHYLOCOCCUS-AUREUS, HYPER-IGE SYNDROME, CUTTING EDGE, PRIMARY IMMUNODEFICIENCY DISEASES, Interleukins, Cell Differentiation, LINKED LYMPHOPROLIFERATIVE DISEASE, Cell biology, B-1 cell, STAT1 Transcription Factor, medicine.anatomical_structure, Antibody Formation, Immunologic Memory, Signal Transduction
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0727e27cbda562a96925f265ca5d114bTest
https://hdl.handle.net/11370/4d7bc2b8-2398-450e-85ae-55b8e29b249bTest