نتائج البحث - "Mice, SCID"

1

Crucial contribution of GPR56/ADGRG1, expressed by breast cancer cells, to bone metastasis formation

المؤلفون: Akira Yamauchi, Shinichi Hashimoto, Hiroyuki Tsuchiya, Tomohisa Baba, Yoshihiro Hayakawa, Soichiro Sasaki, Naofumi Mukaida, Katsuhiro Hayashi, Di Zhang, Sadahiro Iwabuchi, Yamato Tanabe

المصدر: Cancer Science

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce6ac60a9857fb66be1310444abf8e3Test
http://europepmc.org/articles/PMC8645723Test

2

Antitumor effect of WEE1 blockade as monotherapy or in combination with cisplatin in urothelial cancer

المؤلفون: Shusuke Akamatsu, Hideaki Takada, Ryoichi Saito, Takayuki Goto, Akihiro Hamada, Toru Sakatani, Takeshi Sano, Yuki Kita, Kei Mizuno, Keiyu Matsumoto, Osamu Ogawa, Kenji Nakamura, Takashi Kobayashi, Tatsuaki Tsuruyama, Kaoru Murakami

المصدر: Cancer Science

مصطلحات موضوعية: Male, p53, Cancer Research, Cell, cisplatin, Apoptosis, Cell Cycle Proteins, Mice, SCID, Mice, Enzyme Inhibitors, Mitotic catastrophe, Aged, 80 and over, Mice, Inbred BALB C, Drug Synergism, General Medicine, Protein-Tyrosine Kinases, Cell cycle, Treatment Outcome, medicine.anatomical_structure, Oncology, urothelial cancer, Gene Knockdown Techniques, Original Article, Drug Therapy, Combination, Female, cell cycle, medicine.drug, Mice, Nude, Mitosis, Antineoplastic Agents, Pyrimidinones, Transfection, In vivo, Cell Line, Tumor, medicine, Animals, Humans, WEE1, neoplasms, Aged, Cell Proliferation, Cisplatin, business.industry, Cancer, Original Articles, medicine.disease, Xenograft Model Antitumor Assays, Drug Discovery and Delivery, Urinary Bladder Neoplasms, Cancer research, Pyrazoles, Tumor Suppressor Protein p53, business, Ex vivo

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f21b6c3d5d2a3bebac0f2b7b2ddfabaTest
http://hdl.handle.net/2433/277918Test

3

LPCAT1 reprogramming cholesterol metabolism promotes the progression of esophageal squamous cell carcinoma

المؤلفون: Lu Liu, Kairong Han, Mingyue Tao, Zhengwei Zhang, Zhen Song, Tong Gu, Weiyong Yu, Xiaofei Chen, Xiaojuan Yu, Li Zhang, Xiujuan Huang, Chao Luo, Hao Gu, Jing Luo, Yali Jun, Qilong Wang, Su’an Sun

المصدر: Cell Death and Disease, Vol 12, Iss 9, Pp 1-14 (2021)

مصطلحات موضوعية: Male, Cancer Research, Esophageal Neoplasms, Transcription, Genetic, Apoptosis, Mice, SCID, chemistry.chemical_compound, Cell Movement, Mice, Inbred NOD, Medicine, Cell Cycle, 1-Acylglycerophosphocholine O-Acyltransferase, Middle Aged, Prognosis, Neoplasm Proteins, Up-Regulation, Gene Expression Regulation, Neoplastic, Cholesterol, Disease Progression, Female, lipids (amino acids, peptides, and proteins), Esophageal Squamous Cell Carcinoma, Signal Transduction, Immunology, Cellular and Molecular Neuroscience, Downregulation and upregulation, Cell Line, Tumor, Lysophosphatidylcholine acyltransferase 1, Animals, Humans, Neoplasm Invasiveness, PI3K/AKT/mTOR pathway, Cell Proliferation, Base Sequence, QH573-671, business.industry, Cell growth, Cancer, Lipid metabolism, Cell Biology, medicine.disease, Anoikis, digestive system diseases, chemistry, Membrane biogenesis, Cancer research, business, Cytology, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8099230b8eb9d206e594b7c0abe7c3bTest
https://doaj.org/article/5b1194a8b436477984313af0665b8fd3Test

4

MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Nature Communications

مصطلحات موضوعية: Male, Squalene monooxygenase, Antifungal drug, General Physics and Astronomy, Mice, SCID, urologic and male genital diseases, Cohort Studies, Mice, Prostate cancer, chemistry.chemical_compound, Transactivation, Neoplasm Metastasis, Cancer, Aged, 80 and over, Multidisciplinary, Middle Aged, Lipids, Gene Expression Regulation, Neoplastic, Prostatic Neoplasms, Castration-Resistant, Cholesterol, Receptors, Androgen, lipids (amino acids, peptides, and proteins), Transcriptional Activation, Cell death, Cell Survival, Science, Down-Regulation, Urological cancer, General Biochemistry, Genetics and Molecular Biology, Article, Downregulation and upregulation, Cell Line, Tumor, medicine, Animals, Humans, Enzalutamide, Metabolomics, Computer Simulation, Neoplasm Invasiveness, Terbinafine, Aged, Cell Proliferation, Neoplasm Staging, Base Sequence, business.industry, Prostatic Neoplasms, General Chemistry, Prostate-Specific Antigen, medicine.disease, Androgen receptor, Disease Models, Animal, MicroRNAs, Squalene Monooxygenase, chemistry, Drug Resistance, Neoplasm, Cancer research, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6faf70310bba7f4f1c068812b8cc48bTest
https://doaj.org/article/11b1a821ae93404d9aff913722f3970eTest

5

Exosomal circEIF3K from cancer-associated fibroblast promotes colorectal cancer (CRC) progression via miR-214/PD-L1 axis

المؤلفون: Jie Zhang, Kaihua Yang, Chuanqing Bao

المصدر: BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
BMC Cancer

مصطلحات موضوعية: Cancer Research, cancer-associated fibroblast, Apoptosis, Mice, SCID, miR-214, Exosomes, medicine.disease_cause, Exosome, B7-H1 Antigen, Metastasis, circEIF3K, Mice, Cancer-Associated Fibroblasts, Mice, Inbred NOD, Biomarkers, Tumor, Tumor Cells, Cultured, Tumor Microenvironment, Genetics, medicine, Animals, Humans, Neoplasm Invasiveness, RC254-282, Cell Proliferation, Tube formation, Tumor microenvironment, Gene knockdown, business.industry, Research, Cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RNA, Circular, Prognosis, medicine.disease, Xenograft Model Antitumor Assays, Colorectal cancer, Gene Expression Regulation, Neoplastic, MicroRNAs, Oncology, Case-Control Studies, Tumorigenesis, Cancer research, Female, Colorectal Neoplasms, Carcinogenesis, business, Microtubule-Associated Proteins

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3471ce6c721afdf46bbf041c52db3621Test
https://doaj.org/article/683b8a640eef4c62b36425ee6a411ff6Test

6

Patient-derived tumor xenograft and organoid models established from resected pancreatic, duodenal and biliary cancers

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports

مصطلحات موضوعية: endocrine system diseases, Science, Antineoplastic Agents, Mice, SCID, medicine.disease_cause, Article, 03 medical and health sciences, 0302 clinical medicine, Duodenal Neoplasms, Mice, Inbred NOD, Pancreatic cancer, Organoid, Medicine, Animals, Humans, Cancer models, 030304 developmental biology, Cell Proliferation, Cancer, Trametinib, 0303 health sciences, Multidisciplinary, Dose-Response Relationship, Drug, business.industry, MEK inhibitor, medicine.disease, Xenograft Model Antitumor Assays, digestive system diseases, 3. Good health, Organoids, Pancreatic Neoplasms, Biliary Tract Neoplasms, Oncology, 030220 oncology & carcinogenesis, Mutation, Cancer research, Biliary tract cancer, Duodenal adenocarcinoma, KRAS, business, V600E

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3769c8d1aeb392bf740b37078270d8a3Test
https://doaj.org/article/a748f950b73d4012ad6cf5ca93a0e308Test

7

Stomatin-Mediated Inhibition of the Akt Signaling Axis Suppresses Tumor Growth

المؤلفون: Khurelbaatar Tsevelnorov, Akio Shimizu, Akinori Wada, Akihiro Kawauchi, Akira Sato, Mohammad Khusni B Ahmat Amin, Joanne Ern Chi Soh, Masahiro Komeno, Hisakazu Ogita, Le Kim Chi Nguyen, Rasel Molla, Nor Idayu A. Rahman

المصدر: Cancer research. 81(9):2318-2331

مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Stromal cell, Cell, Apoptosis, Cell Communication, Mice, SCID, Transfection, 3-Phosphoinositide-Dependent Protein Kinases, Mice, 03 medical and health sciences, 0302 clinical medicine, Mice, Inbred NOD, medicine, Animals, Humans, Protein kinase B, Aged, Cell Proliferation, Tumor microenvironment, biology, Chemistry, Membrane Proteins, Prostatic Neoplasms, Cancer, Hep G2 Cells, medicine.disease, Xenograft Model Antitumor Assays, Hsp90, Tumor Burden, HEK293 Cells, 030104 developmental biology, medicine.anatomical_structure, Oncology, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, Cancer cell, biology.protein, Cancer research, Stromal Cells, Stomatin, Proto-Oncogene Proteins c-akt, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de32264198bfbc7707618ae598db8a03Test
http://hdl.handle.net/10422/00012980Test

8

MRE11 promotes oral cancer progression through RUNX2/CXCR4/AKT/FOXA2 signaling in a nuclease-independent manner

المؤلفون: Wangta Liu, Stephen Chu-Sung Hu, Tsung-Chen Chi, Yi-Hua Chen, Chih-Jen Huang, Ya-Ching Hsieh, Yen-Yun Wang, Yuk-Kwan Chen, Fang-Yu Tsai, Ya-Wen Chen, Shyng-Shiou F. Yuan, Shih Sheng Jiang, Ruei-Nian Li, Steven Lo

المصدر: Oncogene

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Receptors, CXCR4, Double-strand DNA breaks, Core Binding Factor Alpha 1 Subunit, Mice, SCID, Radiation Tolerance, Article, Metastasis, 03 medical and health sciences, Mice, 0302 clinical medicine, DNA repair complex, Cell Movement, Mice, Inbred NOD, Radioresistance, Cell Line, Tumor, Genetics, medicine, Animals, Humans, Molecular Biology, Protein kinase B, Zebrafish, Cell Proliferation, Nuclease, MRE11 Homologue Protein, Deoxyribonucleases, biology, Cell growth, Oral cancer, Cancer, medicine.disease, Prognosis, Survival Rate, enzymes and coenzymes (carbohydrates), 030104 developmental biology, DNA Repair Enzymes, 030220 oncology & carcinogenesis, Rad50, Cancer research, biology.protein, Hepatocyte Nuclear Factor 3-beta, Heterografts, Female, Mouth Neoplasms, Proto-Oncogene Proteins c-akt, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e2677d17138be0a83de27104568778Test
http://europepmc.org/articles/PMC8134045Test

9

Bladder cancer cell‐intrinsic PD‐L1 signals promote mTOR and autophagy activation that can be inhibited to improve cytotoxic chemotherapy

المؤلفون: Ryan Reyes, Robert S. Svatek, Anand Kornepati, Suresh Kari, Ratna K. Vadlamudi, Tyler J. Curiel, Erica Osta, Yilun Deng, Bogang Wu, Deyi Zhang, Alvaro Padron, Xiujie Sun, Rong Li, Harshita Gupta, Aravind Kancharla

المصدر: Cancer Medicine, Vol 10, Iss 6, Pp 2137-2152 (2021)
Cancer Medicine

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Gene Expression, mTORC1, Mice, SCID, chemotherapy, Deoxycytidine, B7-H1 Antigen, Mice, 0302 clinical medicine, Mice, Inbred NOD, Medicine, Neoplasm Metastasis, Phosphorylation, Melanoma, Original Research, Cancer Biology, Ovarian Neoplasms, Antibiotics, Antineoplastic, biology, Chloroquine, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Oncology, 030220 oncology & carcinogenesis, mTOR, bladder cancer, Female, autophagy, Mechanistic Target of Rapamycin Complex 1, lcsh:RC254-282, 03 medical and health sciences, PD-L1, Cell Line, Tumor, Animals, Humans, Radiology, Nuclear Medicine and imaging, PI3K/AKT/mTOR pathway, Cell Proliferation, Sirolimus, business.industry, Cell growth, Autophagy, Cancer, medicine.disease, Gemcitabine, Mice, Inbred C57BL, 030104 developmental biology, Urinary Bladder Neoplasms, Drug Resistance, Neoplasm, PD‐L1, Cancer research, biology.protein, Cisplatin, business, Ovarian cancer, Proto-Oncogene Proteins c-akt

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1718548b8b2d59ba5826371b29c573b9Test
https://doaj.org/article/e4a5d1a873db407eb7004100b7129f12Test

10

225Ac‐labeled CD33‐targeting antibody reverses resistance to Bcl‐2 inhibitor venetoclax in acute myeloid leukemia models

المؤلفون: Dale Ludwig, Wojciech Dawicki, Ravendra Garg, Kevin J. H. Allen, Ekaterina Dadachova, Eileen M. Geoghegan

المصدر: Cancer Medicine, Vol 10, Iss 3, Pp 1128-1140 (2021)
Cancer Medicine

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, medicine.medical_treatment, CD33, Sialic Acid Binding Ig-like Lectin 3, Apoptosis, 225Ac‐lintuzumab, Mice, SCID, chemistry.chemical_compound, Mice, 0302 clinical medicine, Antineoplastic Agents, Immunological, hemic and lymphatic diseases, Tumor Cells, Cultured, Original Research, Cancer Biology, Sulfonamides, Myeloid leukemia, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Leukemia, Myeloid, Acute, Oncology, Proto-Oncogene Proteins c-bcl-2, 030220 oncology & carcinogenesis, Radioimmunotherapy, Female, medicine.drug, Actinium, Combination therapy, Antineoplastic Agents, acute myeloid leukemia, Antibodies, Monoclonal, Humanized, lcsh:RC254-282, 03 medical and health sciences, medicine, Animals, Humans, Radiology, Nuclear Medicine and imaging, Cell Proliferation, venetoclax, Venetoclax, business.industry, Bcl‐2, Cancer, medicine.disease, Bridged Bicyclo Compounds, Heterocyclic, Xenograft Model Antitumor Assays, 030104 developmental biology, Hypomethylating agent, chemistry, Drug Resistance, Neoplasm, Cytarabine, Cancer research, radioimmunotherapy, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c5b119488da6a01ebf186503bd8d291Test
https://doaj.org/article/af252bdb1a414e8c8cac047a8543fb55Test

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