التفاصيل البيبلوغرافية
العنوان: |
TP53INP2 at the crossroad of apoptosis and autophagy in death receptor signaling. |
المؤلفون: |
Ivanova, Saška1,2,3 saska.ivanova@irbbarcelona.org, Zorzano, Antonio1,2,3 antonio.zorzano@irbbarcelona.org |
المصدر: |
Molecular & Cellular Oncology. 2019, Vol. 6 Issue 5, p1-3. 3p. |
مصطلحات موضوعية: |
*APOPTOSIS, *AUTOPHAGY, *DEATH receptors, *LIGANDS (Biochemistry), *BIOLOGICAL tags |
مستخلص: |
The binding of ligands to death receptors elicits distinct outcomes, such as apoptosis, inflammation and necroptosis, depending on the cellular context. We have recently described that the autophagic protein TP53INP2 favors apoptosis upon death receptor signaling and is a potential biomarker of responsiveness to TRAIL treatment. [ABSTRACT FROM AUTHOR] |
قاعدة البيانات: |
Academic Search Index |