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المؤلفون: Paul J. Emmerson, David J. Hodson, Brandy M. Snider, Nicolas Nunn, Tamer Coskun, Jenna Hunter, Mehdi Boutagouga Boudjadja, Gabriella Aviello, Isabella Culotta, Minrong Ai, Simon M. Luckman, Alessia Costa, Giuseppe D'Agostino, Lourdes Valencia-Torres
المساهمون: Costa, A., Ai, M., Nunn, N., Culotta, I., Hunter, J., Boudjadja, M. B., Valencia-Torres, L., Aviello, G., Hodson, D. J., Snider, B. M., Coskun, T., Emmerson, P. J., Luckman, S. M., D'Agostino, G.
المصدر: Costa, A, Ai, M, Nunn, N, Culotta, I, Hunter, J, Boudjadja, M B, Valencia-Torres, L, Aviello, G, Hodson, D J, Snider, B M, Coskun, T, Emmerson, P J, Luckman, S M & D'Agostino, G 2021, ' Anorectic and aversive effects of GLP-1 receptor agonism are mediated by brainstem cholecystokinin neurons, and modulated by GIP receptor activation ', Molecular Metabolism, vol. 55, 101407 . https://doi.org/10.1016/j.molmet.2021.101407Test
Molecular Metabolism
Molecular Metabolism, Vol 55, Iss, Pp 101407-(2022)مصطلحات موضوعية: Blood Glucose, Male, Glucagon-like peptide-1, endocrine system, Glucose-dependent insulinotropic polypeptide, media_common.quotation_subject, Appetite, Gastric Inhibitory Polypeptide, Brief Communication, Glucagon-Like Peptide-1 Receptor, Receptors, Gastrointestinal Hormone, Mice, Nucleus of the solitary tract, Glucagon-Like Peptide 1, Appetite Depressants, Medicine, Animals, Hypoglycemic Agents, Insulin, Receptor, Internal medicine, Molecular Biology, Glucagon-like peptide 1 receptor, media_common, Cholecystokinin, Neurons, business.industry, Area postrema, digestive, oral, and skin physiology, Brain, Nausea, Cell Biology, Liraglutide, Glucagon, RC31-1245, Mice, Inbred C57BL, Anorectic, Exenatide, Female, Brainstem, business, Neuroscience, hormones, hormone substitutes, and hormone antagonists
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3c8f4b8195f8ad7f7f17bc35a2d9541Test
https://www.research.manchester.ac.uk/portal/en/publications/anorectic-and-aversive-effects-of-glp1-receptor-agonism-are-mediated-by-brainstem-cholecystokinin-neurons-and-modulated-by-gip-receptor-activationTest(97b025ca-ff46-4b48-a59c-edf8df09098e).html -
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المؤلفون: Jimmy F.P. Berbée, Renze Boverhof, Patrick C.N. Rensen, Yanan Wang, Zhuang Li, Amber W Schonk, Mariëtte R. Boon, Arthur C Eibergen, Geerte Hoeke, Folkert Kuipers, Tamer Coskun, Rick Havinga, Martijn Koehorst, Enchen Zhou, Albert K. Groen
المساهمون: Experimental Vascular Medicine, Vascular Medicine, ACS - Atherosclerosis & ischemic syndromes, ACS - Diabetes & metabolism, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Center for Liver, Digestive and Metabolic Diseases (CLDM), Lifestyle Medicine (LM)
المصدر: Cardiovascular Research, 116(10), 1710-1720. OXFORD UNIV PRESS
Cardiovascular research, 116(10), 1710-1720. Oxford University Press
Cardiovascular Research
Cardiovascular Research, 116(10):cvz253, 1710-1720. Oxford University Pressمصطلحات موضوعية: medicine.medical_specialty, Bile acid metabolism, Physiology, Apolipoprotein E3, Colesevelam Hydrochloride, Adrenergic beta-3 Receptor Agonists, Hyperlipidemias, Mice, Transgenic, Dioxoles, Brown adipose tissue, Cholesterol turnover, Bile Acids and Salts, Excretion, Feces, chemistry.chemical_compound, Adipose Tissue, Brown, Physiology (medical), Internal medicine, Enterohepatic Circulation, Intestinal Elimination, Hyperlipidemia, medicine, Animals, Atherosclerosis and Lipid Biology, AcademicSubjects/MED00200, Enterohepatic circulation, Colesevelam, Chemistry, Cholesterol, Reabsorption, Anticholesteremic Agents, Original Articles, Metabolism, medicine.disease, Atherosclerosis, Cholesterol Ester Transfer Proteins, Disease Models, Animal, medicine.anatomical_structure, Endocrinology, Intestinal Absorption, Liver, Hyperlipidaemia, Cardiology and Cardiovascular Medicine, medicine.drug
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0520492220ce293e183a012ad046b084Test
https://hdl.handle.net/1887/3182382Test -
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المؤلفون: Geerte Hoeke, Anne Reifel Miller, Patrick C.N. Rensen, Lea H. Dib, Bharat Shimpukade, Trond Ulven, Tamer Coskun, Anthony Okolo, Sander Kooijman, Maaike Schilperoort, Natarin Caengprasath, Mark Christian, Yi-Wah Chan, Aylin C. Hanyaloglu, Andrea D. van Dam, Sami Damak, Isabel M. Mol, Irina G. Shabalina
المساهمون: Biotechnology and Biological Sciences Research Council (BBSRC)
المصدر: EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 10, Iss 3, Pp n/a-n/a (2018)
EMBO Molecular Medicine, 10(3)
Schilperoort, M, van Dam, A D, Hoeke, G, Shabalina, I G, Okolo, A, Hanyaloglu, A C, Dib, L H, Mol, I M, Caengprasath, N, Chan, Y-W, Damak, S, Miller, A R, Coskun, T, Shimpukade, B, Ulven, T, Kooijman, S, Rensen, P C & Christian, M 2018, ' The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat ', EMBO Molecular Medicine, vol. 10, no. 3, e8047 . https://doi.org/10.15252/emmm.201708047Testمصطلحات موضوعية: 0301 basic medicine, Male, Medicine (General), Ca, GPR120, Adipocytes, White, Gene Expression Regulation/drug effects, Phenylpropionates/pharmacology, QH426-470, Mitochondrion, Receptors, G-Protein-Coupled, Oxygen Consumption/drug effects, Adipose Tissue, Brown, Receptors, G-Protein-Coupled/agonists, Brown adipose tissue, lipid metabolism, Glucose/metabolism, Adipose Tissue, Brown/drug effects, Research Articles, Uncoupling Protein 1, Adiposity, Phenylpropionates, Chemistry, Cell Differentiation, 11 Medical And Health Sciences, Lipids, Mitochondria/drug effects, mitochondria, Ca2+, medicine.anatomical_structure, Adipocytes, Brown, Molecular Medicine, Adipocytes, Brown/cytology, Mitochondrial fission, Oxidation-Reduction, Research Article, Agonist, medicine.medical_specialty, medicine.drug_class, Adipose Tissue, White, Cell Respiration, Adiposity/drug effects, Carbohydrate metabolism, Models, Biological, Adipocytes, White/cytology, 03 medical and health sciences, R5-920, Oxygen Consumption, Adipose Tissue, White/drug effects, Internal medicine, Cell Respiration/drug effects, Genetics, medicine, Animals, Body Weight/drug effects, Pharmacology & Drug Discovery, Biphenyl Compounds, Body Weight, Uncoupling Protein 1/metabolism, Lipid metabolism, brown adipose tissue, 06 Biological Sciences, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Metabolism, Glucose, Gene Expression Regulation, Cell Differentiation/drug effects, Biphenyl Compounds/pharmacology, Thermogenesis, RC
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e500a414f38fbfef93af89f8a97f0493Test
http://wrap.warwick.ac.uk/97936/1/GPR120-agonist-TUG-391-promotes-Christian-2018.pdfTest -
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المؤلفون: Richard G. Peterson, Karen M. Zimmerman, M. Dodson Michael, Bria L. Sneed, Paul J. Emmerson, Brian A. Droz, Charles V. Jackson, Tamer Coskun
المصدر: PLoS ONE, Vol 12, Iss 6, p e0179808 (2017)
PLoS ONEمصطلحات موضوعية: 0301 basic medicine, Leptin, Blood Glucose, Male, Physiology, medicine.medical_treatment, Peptide Hormones, Type 2 diabetes, Biochemistry, Fats, Eating, Mice, 0302 clinical medicine, Endocrinology, Hyperinsulinemia, Medicine and Health Sciences, Medicine, Insulin, 2. Zero hunger, Multidisciplinary, Organic Compounds, Monosaccharides, Animal Models, Lipids, 3. Good health, Chemistry, Physiological Parameters, Experimental Organism Systems, Physical Sciences, medicine.symptom, Research Article, medicine.medical_specialty, Offspring, Science, Carbohydrates, 030209 endocrinology & metabolism, Mouse Models, Research and Analysis Methods, Diet, High-Fat, 03 medical and health sciences, Insulin resistance, Model Organisms, Diabetes mellitus, Internal medicine, Animals, Obesity, Pancreas, Nutrition, Diabetic Endocrinology, business.industry, Body Weight, Organic Chemistry, Chemical Compounds, Biology and Life Sciences, medicine.disease, Hormones, Diet, 030104 developmental biology, Glucose, Diabetes Mellitus, Type 2, business, Weight gain
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff96d25ea08c7654451bfe234ee4c5aTest
https://doaj.org/article/bb9f14c1cae741f99f99a57996878039Test -
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المؤلفون: Audrey Ayer, Soazig Le Lay, Cédric Le May, Tamer Coskun, Xavier Prieur, Jocelyne Magré, L. Dollet, Quentin Venara, Ruth E. Gimeno, Bertrand Cariou, Clara Levrel, Andrew C. Adams
المساهمون: unité de recherche de l'institut du thorax UMR1087 UMR6291 (ITX), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Stress Oxydant et Pathologies Métaboliques (SOPAM), Université d'Angers (UA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)
المصدر: Diabetes
Diabetes, 2016, Equipe 5, 65 (11), pp.3410--3417. ⟨10.2337/db16-0327⟩
Diabetes, American Diabetes Association, 2016, 65 (11), pp.3410-3417. ⟨10.2337/db16-0327⟩مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, FGF21, Endocrinology, Diabetes and Metabolism, [SDV]Life Sciences [q-bio], Adipocytes, White, Blotting, Western, White adipose tissue, Biology, Seipin, Mice, 03 medical and health sciences, chemistry.chemical_compound, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, 3T3-L1 Cells, GTP-Binding Protein gamma Subunits, Adipocyte, Internal medicine, Internal Medicine, medicine, [SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO], Animals, Homeostasis, Adiponectin secretion, RNA, Messenger, ComputingMilieux_MISCELLANEOUS, Mice, Knockout, Gene knockdown, Adiponectin, Adipose tissue loss, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, Heterotrimeric GTP-Binding Proteins, 3. Good health, Fibroblast Growth Factors, 030104 developmental biology, Endocrinology, Adipose Tissue, chemistry
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc7641d61bcbaab81e84bf97c38a83bbTest
https://hal.archives-ouvertes.fr/hal-01831750Test -
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المؤلفون: Daniel A. Briere, Thomas E. Fitch, Carmen Dominguez, Chen S. Suen, M. Dodson Michael, Xiaoping Ruan, Yanping Xu, Sonia Maria Gutierrez Sanfeliciano, Tamer Coskun, Carlos Montero, Angela M. Siesky, Christine C. Cheng
المصدر: PLoS ONE
PLoS ONE, Vol 10, Iss 8, p e0136873 (2015)مصطلحات موضوعية: Agonist, Male, medicine.medical_specialty, medicine.drug_class, medicine.medical_treatment, Drug Evaluation, Preclinical, lcsh:Medicine, Enteroendocrine cell, Receptors, G-Protein-Coupled, Small Molecule Libraries, Glucagon-Like Peptide 1, Internal medicine, Weight Loss, medicine, Animals, Humans, Hypoglycemic Agents, Peptide YY, lcsh:Science, Mice, Knockout, Glucose tolerance test, Multidisciplinary, Bile acid, medicine.diagnostic_test, Chemistry, Insulin, Gallbladder, lcsh:R, digestive, oral, and skin physiology, Glucose Tolerance Test, G protein-coupled bile acid receptor, Mice, Inbred C57BL, Endocrinology, medicine.anatomical_structure, HEK293 Cells, Gene Expression Regulation, lcsh:Q, hormones, hormone substitutes, and hormone antagonists, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef66eca944dae6da54c6da25bc20d12Test
http://europepmc.org/articles/PMC4551797Test -
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المؤلفون: Alexei Kharitonenkov, Paul J. Emmerson, Andrew C. Adams, Kostas Tsintzas, Francis J. P. Ebling, Ricardo J. Samms, Tamer Coskun, Maxine J Fowler, Scott Cooper
مصطلحات موضوعية: Male, medicine.medical_specialty, FGF21, Phodopus, media_common.quotation_subject, Photoperiod, Hamster, White adipose tissue, Biology, Behavioral Neuroscience, Eating, Endocrinology, Internal medicine, Cricetinae, Brown adipose tissue, Ketogenesis, medicine, Endocrine system, Animals, media_common, Endocrine and Autonomic Systems, Catabolism, Appetite, Fibroblast Growth Factors, medicine.anatomical_structure, Appetite, Metabolic rate, Energy expenditure, Photoperiod, Energy Metabolism
وصف الملف: application/pdf; PDF
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de11d9694c7bc47fc154dc4878c5c32eTest
http://eprints.nottingham.ac.uk/34343Test/ -
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المؤلفون: Bumol Thomas Frank, Christopher C. Frye, John Michael Beals, Tamer Coskun, Alexei Kharitonenkov, Radhakrishnan Rathnachalam, James D. Dunbar, Victor J. Wroblewski, Beth A. Strifler, Shun Li, Christine C. Cheng, Anja Koester, David E. Moller, Radmila Micanovic, Amy M. Ford
المصدر: PLoS ONE
PLoS ONE, Vol 8, Iss 3, p e58575 (2013)مصطلحات موضوعية: Male, Models, Molecular, Drugs and Devices, FGF21, Drug Research and Development, Non-Clinical Medicine, Protein Conformation, lcsh:Medicine, Gene Expression, Biology, Fibroblast growth factor, Cardiovascular Pharmacology, Pichia, Pichia pastoris, Cell Line, Mice, Endocrinology, In vivo, Animals, Humans, lcsh:Science, Klotho Proteins, chemistry.chemical_classification, Diabetic Endocrinology, Multidisciplinary, Endocrine Physiology, Protein Stability, lcsh:R, Drug Information, Wild type, Temperature, Genetic Variation, Membrane Proteins, 3T3 Cells, Hep G2 Cells, biology.organism_classification, In vitro, Recombinant Proteins, Amino acid, Fibroblast Growth Factors, Biopharmaceutical, chemistry, Biochemistry, Amino Acid Substitution, Metabolic Disorders, Drug Design, Medicine, lcsh:Q, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d743e028a69d60dcee0846768123348dTest
http://europepmc.org/articles/PMC3594191Test -
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المصدر: PLoS ONE, Vol 7, Iss 11, p e49977 (2012)
PLoS ONEمصطلحات موضوعية: Scaffold protein, Male, medicine.medical_specialty, FGF21, Anatomy and Physiology, Mouse, Adipose Tissue, White, Adipose tissue, lcsh:Medicine, Endocrine System, Biology, Fibroblast growth factor, Mice, Model Organisms, Endocrinology, In vivo, Internal medicine, Integrative Physiology, Brown adipose tissue, medicine, Glucose homeostasis, Animals, lcsh:Science, Klotho Proteins, Regulation of gene expression, Mice, Knockout, Diabetic Endocrinology, Multidisciplinary, lcsh:R, Membrane Proteins, Animal Models, Cell biology, Fibroblast Growth Factors, medicine.anatomical_structure, Gene Expression Regulation, Liver, Medicine, Female, lcsh:Q, Energy Metabolism, Physiological Processes, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d9fac3e8e74e9bf8c402c05b4298c34Test
http://europepmc.org/articles/PMC3507945?pdf=renderTest