نتائج البحث

1

Ontogeny of small intestinal drug transporters and metabolizing enzymes based on targeted quantitative proteomicsS

المؤلفون: Apoorva Kotian, Nico Kist, Rene M. H. Wijnen, Saskia N. de Wildt, Johan Nicolaï, Anna-Lena Ungell, Paul Cutler, Márton Kiss, Frans G. M. Russel, Richard Mbasu, M. G. Mooij, Karin Barnouin

المساهمون: Pediatric Surgery

المصدر: Drug Metabolism and Disposition, 49, 12, pp. 1038-1046
Drug Metabolism and Disposition, 49(12), 1038-1046. American Society for Pharmacology and Experimental Therapeutics
Drug Metabolism and Disposition, 49, 1038-1046

مصطلحات موضوعية: Adult, Metabolic Clearance Rate, Biological Transport, Active, Pharmaceutical Science, Ileum, Pharmacology, Peptide Transporter 1, digestive system, Jejunum, All institutes and research themes of the Radboud University Medical Center, SDG 3 - Good Health and Well-being, Tandem Mass Spectrometry, Multidrug Resistance Protein 1, Intestine, Small, medicine, ATP Binding Cassette Transporter, Subfamily G, Member 2, Cytochrome P-450 CYP3A, Humans, Glucuronosyltransferase, Child, Enzyme Assays, Organic cation transport proteins, biology, Multidrug resistance-associated protein 2, Peptide transporter 1, Age Factors, Membrane Transport Proteins, Multidrug Resistance-Associated Protein 2, Neoplasm Proteins, Gene Ontology, medicine.anatomical_structure, Monocarboxylate transporter 1, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], Inactivation, Metabolic, biology.protein, Renal disorders Radboud Institute for Health Sciences [Radboudumc 11], Drug metabolism, Chromatography, Liquid

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be6345e070847ec4b94376735da97969Test
https://pure.eur.nl/en/publications/1403454e-7805-47b0-8fbc-c2871a463613Test

2

Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes

المؤلفون: Clare Megson, Anna E. Long, Isabel V. Wilson, F. Susan Wong, Rachel J Aitken, Stephanie J. Hanna, Kathleen M Gillespie, Joanne Boldison

المصدر: Diabetologia
Boldison, J, Long, A E, Aitken, R J, Wilson, I V, Hanna, S, Wong, F S & Gillespie, K M 2022, ' Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes ', Diabetologia, vol. 65, no. 2, pp. 343-355 . https://doi.org/10.1007/s00125-021-05595-0Test

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460b8482e2433313b173be3da48524a8Test
http://europepmc.org/articles/PMC8741669Test

3

Lower bone mineral density and higher bone resorption marker levels in premenopausal women with type 1 diabetes in Japan

المؤلفون: Muneto Yoshioka, Fumi Yoshioka, Naoki Sakane, Tomokazu Watanabe, Takashi Murata, Yaeko Kawaguchi, Kunio Saeki, Shinsuke Nirengi

المصدر: Journal of Diabetes Investigation, Vol 12, Iss 9, Pp 1689-1696 (2021)
Journal of Diabetes Investigation

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Heel, Endocrinology, Diabetes and Metabolism, Osteoporosis, 030209 endocrinology & metabolism, Tartrate‐resistant acid phosphatase‐5b, Bone resorption, Diseases of the endocrine glands. Clinical endocrinology, Bone remodeling, 03 medical and health sciences, 0302 clinical medicine, Japan, Type 1 diabetes mellitus, Diabetes mellitus, Internal medicine, Internal Medicine, medicine, Bone mineral density, Humans, 030212 general & internal medicine, Bone Resorption, Bone mineral, Type 1 diabetes, business.industry, Articles, General Medicine, Middle Aged, Prognosis, medicine.disease, RC648-665, Postmenopause, Bone Diseases, Metabolic, Diabetes Mellitus, Type 1, Clinical Science and Care, medicine.anatomical_structure, Premenopause, Female, Original Article, Calcaneus, business, Biomarkers, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73133ae0033e4e07c0cadd636882b138Test
https://doaj.org/article/fbe0f23e15154ca3bc2388a75b425908Test

4

Integrin αvβ5 heterodimer is a specific marker of human pancreatic beta cells

المؤلفون: Jacqueline V. Schiesser, Thomas Loudovaris, Helen E. Thomas, Edouard G. Stanley, Andrew G. Elefanty

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::932b8419e0cfd10e677c6085465d5e16Test
https://doaj.org/article/dcab1ff3fe334cd4b5b2b617cf023918Test

5

Identification and characterisation of tertiary lymphoid organs in human type 1 diabetes

المؤلفون: Nadir Kadri, Sarah J. Richardson, Lydia Sorokin, Eva Korpos, Sophie Loismann, Clais R. Findeisen, Noel G. Morgan, Alberto Pugliese, Frank Arfuso, George W. Burke, Marika Bogdani

المصدر: Diabetologia

مصطلحات موضوعية: 0301 basic medicine, Male, Pathology, Endocrinology, Diabetes and Metabolism, Autoimmunity, medicine.disease_cause, Mice, 0302 clinical medicine, Tertiary lymphoid organs, Mice, Inbred NOD, Child, NOD mice, Aged, 80 and over, Middle Aged, medicine.anatomical_structure, Type 1 diabetes, Fibroblastic reticular cells, Child, Preschool, Lymph node, Female, Beta cell, Adult, medicine.medical_specialty, Basement membrane, Adolescent, T cell, High endothelial venules, 030209 endocrinology & metabolism, Biology, Article, 03 medical and health sciences, Islets of Langerhans, Young Adult, Internal Medicine, medicine, Animals, Humans, Pancreas, B cell, Aged, Autoantibodies, Transplantation, medicine.disease, 030104 developmental biology, Diabetes Mellitus, Type 1, Tertiary Lymphoid Structures, Microscopy, Fluorescence, Reticular fibres, Insulitis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f333af12269efbba20d5e0fefe7a11dfTest
http://europepmc.org/articles/PMC8187221Test

6

Ex vivo isolation, expansion and bioengineering of CCR7+CD95-/or CD62L+CD45RA+ tumor infiltrating lymphocytes from acute myeloid leukemia patients’ bone marrow

المؤلفون: Samiksha Wasnik, Jeffrey Xiao, Chien-Shing Chen, Do Hyun Kim, Mark E. Reeves, David J. Baylink, Ashley Howard, Olivia L. Francis, Hector Moz, Saied Mirshahidi, Huynh Cao, Yi Xu, Guido Marcucci

المصدر: Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1252-1260 (2021)

مصطلحات موضوعية: Male, Cancer Research, medicine.medical_treatment, Cell Separation, Mice, FACS, flow cytometry, T-Lymphocyte Subsets, hemic and lymphatic diseases, PD-1, Medicine, L-Selectin, AML, acute myeloid leukemia, RC254-282, biology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Myeloid leukemia, hemic and immune systems, Middle Aged, Adoptive Transfer, Adoptive cell therapy, CAR-T, Leukemia, Myeloid, Acute, medicine.anatomical_structure, BMMNC, bone marrow mononuclear cells, CD95, Heterografts, Female, Immunotherapy, Adult, Original article, Receptors, CCR7, CD3, T cell, chemical and pharmacologic phenomena, Bioengineering, Bone Marrow Cells, Peripheral blood mononuclear cell, Lymphocytes, Tumor-Infiltrating, CD62L, CD45RA, Animals, Humans, Bone marrow, fas Receptor, Aged, Programmed cell death protein 1, Acute myeloid leukemia, Tumor-infiltrating lymphocytes, business.industry, HSCs, hematopoietic stem cells, Naïve T, Interleukin, IL, interleukin, TILs, tumor-infiltrating lymphocytes, biology.protein, Cancer research, Tumor-Infiltrating Lymphocytes, BM, bone marrow, Leukocyte Common Antigens, business, Ex vivo, CCR7

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8631938224952c24db64ba170babb9e6Test
http://europepmc.org/articles/PMC8603025Test

7

Matrix Metalloproteinases in Human Decidualized Endometrial Stromal Cells

المؤلفون: Yoshiko Hashimoto, Yoji Hisamatsu, Susumu Tanaka, Hiromi Murata, Hiroaki Tsubokura, Masaaki Kitada, Hidetaka Okada

المصدر: Current Issues in Molecular Biology, Vol 43, Iss 146, Pp 2111-2123 (2021)
Current Issues in Molecular Biology; Volume 43; Issue 3; Pages: 2111-2123

مصطلحات موضوعية: Adult, Microbiology (medical), MMP3, Stromal cell, MMP10, QH301-705.5, MMP: matrix metalloprotease, TIMP: tissue inhibitor of metalloproteinase, HAND2: heart and neural crest derivatives expressed 2, SNAI1: snail family transcriptional repressor 1, Matrix metalloproteinase, Microbiology, Endometrium, Young Adult, Decidua, medicine, Humans, Biology (General), Molecular Biology, Cells, Cultured, reproductive and urinary physiology, biology, urogenital system, Decidualization, Tissue Inhibitor of Metalloproteinases, General Medicine, Middle Aged, Matrix Metalloproteinases, Cell biology, medicine.anatomical_structure, Gene Expression Regulation, embryonic structures, biology.protein, Female, Steroids, MMP15, Stromal Cells, HAND2, Biomarkers

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07876acbb054f37bbdb33edbf95432e5Test
https://www.mdpi.com/1467-3045/43/3/146Test

8

Increased ratio of sST2/LVMI predicted cardiovascular mortality and heart failure rehospitalization in heart failure with reduced ejection fraction patients: a prospective cohort study

المؤلفون: Zhexun Lian, Mingqiang Fu, Jingmin Zhou, Xiaotong Cui, Junbo Ge, Mengying Xu, Fuhai Li, Hui Xin

المصدر: BMC Cardiovascular Disorders, Vol 21, Iss 1, Pp 1-10 (2021)
BMC Cardiovascular Disorders

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Time Factors, Diastole, Heart failure, Patient Readmission, Risk Assessment, Ventricular Function, Left, Predictive Value of Tests, Risk Factors, Internal medicine, medicine, Humans, Diseases of the circulatory (Cardiovascular) system, Prospective Studies, Interventricular septum, Prospective cohort study, Soluble suppression of tumorigenicity 2, Aged, Cardiac remodeling, Ejection fraction, Ventricular Remodeling, Proportional hazards model, business.industry, Hazard ratio, Stroke Volume, Middle Aged, medicine.disease, Heart failure with reduced ejection fraction, Interleukin-1 Receptor-Like 1 Protein, Magnetic Resonance Imaging, Progression-Free Survival, Cardiac surgery, medicine.anatomical_structure, Echocardiography, RC666-701, Cardiology, Female, Cardiology and Cardiovascular Medicine, business, Biomarkers, Left ventricular mass index, Research Article, Heart Failure, Systolic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8acf5350a95acef7443b8770df6f59daTest
https://doaj.org/article/8689d0f3811f40829023f669a2059f3dTest

9

Healthy and preeclamptic pregnancies show differences in Guanylate-Binding Protein-1 plasma levels

المؤلفون: Rik H. J. Beernink, Thomas I. F. H. Cremers, Marijke M. Faas, Maria G. van Pampus, Joost H.N. Schuitemaker, Sicco A. Scherjon

المساهمون: Analytical Biochemistry, Medicinal Chemistry and Bioanalysis (MCB), Reproductive Origins of Adult Health and Disease (ROAHD), Translational Immunology Groningen (TRIGR)

المصدر: Pregnancy Hypertension, 25, 18-24. ELSEVIER SCI LTD

مصطلحات موضوعية: Placental growth factor, Adult, Endothelium, Placenta, 030204 cardiovascular system & hematology, PERIPHERAL-BLOOD, Proinflammatory cytokine, Preeclampsia, SERUM, Andrology, ACTIVATION, 03 medical and health sciences, 0302 clinical medicine, Pre-Eclampsia, Endothelial cell, GTP-Binding Proteins, Pregnancy, Internal Medicine, medicine, Humans, RNA, Messenger, REGULATORY T-CELLS, reproductive and urinary physiology, PLACENTAL GROWTH-FACTOR, FETAL, Fetus, 030219 obstetrics & reproductive medicine, HYPERTENSION, business.industry, GBP-1, EXTRACELLULAR VESICLES, Obstetrics and Gynecology, Trophoblast, Endothelial Cells, medicine.disease, ENDOTHELIAL-CELLS, medicine.anatomical_structure, MONOCYTES, Case-Control Studies, Female, business, Guanylate binding protein 1

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7621b510b33f21da1a2422bdee296a1aTest
https://hdl.handle.net/11370/a28d5b78-9d0a-49ad-9cf3-c6d120f64704Test

10

Multiple endocrine neoplasia type 1 with a frameshift mutation in its gene accompanied by a giant cervical lipoma and multiple fatty deposits in the pancreas: case report

المؤلفون: Hideaki Kaneto, Masashi Shimoda, Shuhei Nakanishi, Kohei Kaku, Shinji Kamei, Tomohiko Kimura, Atsushi Obata, Yoshiro Fushimi, Junpei Sanada, Fuminori Tatsumi, Tomoatsu Mune

المصدر: BMC Endocrine Disorders, Vol 21, Iss 1, Pp 1-5 (2021)
BMC Endocrine Disorders

مصطلحات موضوعية: Adult, Male, Pathology, medicine.medical_specialty, congenital, hereditary, and neonatal diseases and abnormalities, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Case Report, Germline, Diseases of the endocrine glands. Clinical endocrinology, Frameshift mutation, Proto-Oncogene Proteins, medicine, Multiple Endocrine Neoplasia Type 1, Humans, MEN1, A giant cervical lipoma, Multiple endocrine neoplasia, Frameshift Mutation, Parathyroidectomy, business.industry, Pancreatic Diseases, General Medicine, Lipoma, medicine.disease, Prognosis, RC648-665, Pancreatic endocrine tumor, medicine.anatomical_structure, Multiple fatty deposits in the pancreas, Pancreas, business, Primary hyperparathyroidism

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bda79ae2f395f76272171ea896e299a7Test
https://doaj.org/article/8c88e3dc93f8443f96a16f8ac303e2baTest

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