نتائج البحث

1

Soluble programmed cell death-1 predicts hepatocellular carcinoma development during nucleoside analogue treatment

المؤلفون: Hiroyuki Motoyama, Norifumi Kawada, Kohei Kotani, Akihiro Tamori, Naoshi Odagiri, Hideki Fujii, Hoang Hai, Le Thi Thanh Thuy, Atsushi Hagihara, Minh Phuong Dong, Masaru Enomoto, Ritsuzo Kozuka, Etsushi Kawamura, Sawako Uchida-Kobayashi, Kanako Yoshida

المصدر: Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Scientific Reports

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4450d2a03fa611a7dd2cf18678b8b541Test
https://doaj.orgTest/article/68f24d6e6a1041038229292cc77e750c

2

Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes

المؤلفون: Clare Megson, Anna E. Long, Isabel V. Wilson, F. Susan Wong, Rachel J Aitken, Stephanie J. Hanna, Kathleen M Gillespie, Joanne Boldison

المصدر: Diabetologia
Boldison, J, Long, A E, Aitken, R J, Wilson, I V, Hanna, S, Wong, F S & Gillespie, K M 2022, ' Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes ', Diabetologia, vol. 65, no. 2, pp. 343-355 . https://doi.org/10.1007/s00125-021-05595-0Test

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460b8482e2433313b173be3da48524a8Test
http://europepmc.org/articles/PMC8741669Test

3

H3K23/H3K36 hypoacetylation and HDAC1 up-regulation are associated with adverse consequences in obstructive sleep apnea patients

المؤلفون: Chang-Chun Hsiao, Ting-Ya Wang, Mao-Chang Su, C Lee, Yong-Yong Lin, Meng-Chih Lin, Po-Yuan Hsu, Hsin-Ching Lin, Yung-Che Chen, Chia-Wei Liou, Chien-Hung Chin

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports

مصطلحات موضوعية: Male, Jumonji Domain-Containing Histone Demethylases, THP-1 Cells, medicine.medical_treatment, Excessive daytime sleepiness, Histone Deacetylase 1, Diseases, medicine.disease_cause, Cohort Studies, Histones, Medicine, Continuous positive airway pressure, Hypoxia, Promoter Regions, Genetic, Sleep Apnea, Obstructive, Multidisciplinary, biology, Continuous Positive Airway Pressure, Molecular medicine, Intermittent hypoxia, Acetylation, Middle Aged, Up-Regulation, Histone, C-Reactive Protein, NADPH Oxidase 1, Female, medicine.symptom, Adult, medicine.medical_specialty, Polysomnography, Science, Disorders of Excessive Somnolence, Peripheral blood mononuclear cell, Article, Sleep Apnea Syndromes, Medical research, Internal medicine, Humans, business.industry, Snoring, DNA Methylation, medicine.disease, HDAC1, Obstructive sleep apnea, Endocrinology, Case-Control Studies, biology.protein, Leukocytes, Mononuclear, business, Oxidative stress, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5df41e5c83da43011517e8da1818415Test
https://doaj.orgTest/article/7aa0ddc6b9dc4f28aa0dbb61d068aad7

4

Investigation of the relationship between immune checkpoints and mismatch repair deficiency in recurrent and nonrecurrent glioblastoma

المؤلفون: Mustafa Emre Ercin, Ismail Saygin, Emel Çakir

المصدر: Turkish Journal of Medical Sciences

مصطلحات موضوعية: Oncology, Adult, Male, medicine.medical_specialty, Programmed cell death, Adolescent, medicine.medical_treatment, Programmed Cell Death 1 Receptor, DNA Mismatch Repair, Article, B7-H1 Antigen, Young Adult, Immune system, Neoplastic Syndromes, Hereditary, Internal medicine, PMS2, programmed cell death protein ligand 1 (PD-L1), Medicine, Humans, Child, Immune Checkpoint Inhibitors, Aged, Aged, 80 and over, business.industry, Brain Neoplasms, Microsatellite instability, General Medicine, Immunotherapy, Middle Aged, medicine.disease, Immune checkpoint, mismatch repair, programmed cell death protein 1 (PD-1), Child, Preschool, Immunohistochemistry, DNA mismatch repair, Female, Microsatellite Instability, Neoplasm Recurrence, Local, business, Glioblastoma, Colorectal Neoplasms

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a44b4cb671bcd3f1641f45f158cabf5bTest
http://europepmc.org/articles/PMC8569775Test

5

Serum urate and cardiovascular events in the DCCT/EDIC study

المؤلفون: Amisha Wallia, Samuel Dagogo-Jack, Ionut Bebu, Trevor J. Orchard, Barbara H. Braffett, Timothy J. Lyons, Alicia J. Jenkins, Arpita Basu, W. Timothy Garvey, Maria F. Lopes-Virella, John M. Lachin

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db6a0485c835ecd5ee1065359316a30Test
https://doaj.orgTest/article/f9fee4388877495b97606fb3d560869c

6

Insulin micro-secretion in Type 1 diabetes and related microRNA profiles

المؤلفون: Anthony C Keech, Yoon Hi Cho, Ryan J. Farr, Emma S. Scott, David N O'Neal, Anandwardhan A. Hardikar, Paul Z. Benitez-Aguirre, Mugdha V. Joglekar, Andrzej S. Januszewski, Luke M. Carroll, Alicia J. Jenkins, Maria E. Craig, Yik Wen Loh, Wilson K. M. Wong, Kim C. Donaghue

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports

مصطلحات موضوعية: Blood Glucose, Male, 0301 basic medicine, Diabetes duration, medicine.medical_treatment, Autoimmunity, 0302 clinical medicine, Insulin-Secreting Cells, Insulin Secretion, Medicine, Child, Aged, 80 and over, Multidisciplinary, C-Peptide, Age Factors, Middle Aged, Type 1 diabetes, Female, Adult, medicine.medical_specialty, Adolescent, Science, 030209 endocrinology & metabolism, Article, Young Adult, 03 medical and health sciences, Diabetes mellitus, Internal medicine, microRNA, Humans, Secretion, Circulating MicroRNA, Insulin secretion, Aged, Autoantibodies, Glycated Hemoglobin, business.industry, Insulin, medicine.disease, MicroRNAs, Diabetes Mellitus, Type 1, 030104 developmental biology, Endocrinology, Gene Expression Regulation, Genetic markers, Age of onset, business, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd5b712c5082c4c879f559920494d80Test
https://doaj.orgTest/article/b1ec56fdb12a4c0cb5cb32be78d2f006

7

Pancreatic beta cell autophagy is impaired in type 1 diabetes

المؤلفون: Amelia K. Linnemann, Charanya Muralidharan, Abass M. Conteh, Pascal de Boer, Jeroen Kuipers, Michelle Marasco, Justin J. Crowder

المصدر: Diabetologia, 64(4), 865-877. SPRINGER
Diabetologia

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Autophagosome, medicine.medical_specialty, Adolescent, Endocrinology, Diabetes and Metabolism, Autophagy-Related Proteins, Nod, Article, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Mice, Inbred NOD, Insulin-Secreting Cells, Internal medicine, Diabetes mellitus, Macroautophagy, Internal Medicine, medicine, Autophagy, Animals, Humans, NOD mice, Proinsulin, Type 1 diabetes, business.industry, Autoantibody-positive, medicine.disease, Lysosome, Disease Models, Animal, Diabetes Mellitus, Type 1, 030104 developmental biology, Endocrinology, Crinophagy, Case-Control Studies, Female, Beta cell, Lysosomes, business, 030217 neurology & neurosurgery, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aca8a2e71e6e61e43eb7bea2f3d7a3e4Test
https://doi.org/10.1007/s00125-021-05387-6Test

8

The association of polypharmacy and high-risk drug classes with adverse health outcomes in the Scottish population with type 1 diabetes

المؤلفون: Rory J. McCrimmon, John A. McKnight, Naveed Sattar, Anita Jeyam, Joseph E. O'Reilly, Thomas M Caparrotta, Graham P. Leese, Brian Kennon, Sarah H. Wild, Hohn Andreas, Robert S. Lindsay, Helen M. Colhoun, Paul M. McKeigue, Stuart J. McGurnaghan, Luke A K Blackbourn

المساهمون: University of St Andrews. School of Geography & Sustainable Development

المصدر: Diabetologia
Colhoun, H M 2021, ' The association of polypharmacy and high-risk drug classes with adverse health outcomes in the Scottish population with type 1 diabetes ', Diabetologia, vol. 64, no. 6, pp. 1309-1319 . https://doi.org/10.1007/s00125-021-05394-7Test, https://doi.org/10.1007/s00125-021-05394-7Test, https://doi.org/10.1007/s00125-021-05394-7Test

مصطلحات موضوعية: Male, Databases, Factual, Endocrinology, Diabetes and Metabolism, E-DAS, 030204 cardiovascular system & hematology, 0302 clinical medicine, RA0421, RA0421 Public health. Hygiene. Preventive Medicine, DKA, Insulin, 030212 general & internal medicine, Child, media_common, Aged, 80 and over, education.field_of_study, Middle Aged, Type 1 diabetes, Child, Preschool, Female, Drug, Adult, RM, medicine.medical_specialty, Diabetic ketoacidosis, Adolescent, media_common.quotation_subject, Population, Article, 03 medical and health sciences, Young Adult, SDG 3 - Good Health and Well-being, Internal medicine, Diabetes mellitus, Internal Medicine, medicine, Humans, Hypoglycemic Agents, Acute complications of diabetes, Medical prescription, Mortality, education, Aged, MCC, Polypharmacy, Proportional hazards model, business.industry, Infant, Newborn, Multimorbidity, Infant, medicine.disease, High-risk prescribing, RM Therapeutics. Pharmacology, Ageing, Diabetes Mellitus, Type 1, Scotland, Medication reviews, Accidental Falls, business, Hypoglycaemia

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b22fe7332bf78f9b04506476b1e5deTest
http://europepmc.org/articles/PMC8099818Test

9

Restoration of HBV-specific CD8+ T-cell responses by sequential low-dose IL-2 treatment in non-responder patients after IFN-α therapy

المؤلفون: Zhigang Tian, Xiaokun Shen, Rui Sun, Chuang Guo, Binqing Fu, Haiming Wei, Jiabin Li, Dongyao Wang, Ying Ye, Junfei Zhang, Yanyan Liu

المصدر: Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-13 (2021)
Signal Transduction and Targeted Therapy

مصطلحات موضوعية: Adult, CD4-Positive T-Lymphocytes, Male, Cell biology, Hepatitis B virus, Cancer Research, Adolescent, QH301-705.5, Programmed Cell Death 1 Receptor, CD8-Positive T-Lymphocytes, medicine.disease_cause, T-Lymphocytes, Regulatory, Article, Young Adult, Hepatitis B, Chronic, Immune system, Interferon, Drug Resistance, Viral, Genetics, medicine, Humans, Cytotoxic T cell, Hepatitis B e Antigens, IL-2 receptor, Biology (General), Aged, business.industry, Interleukin-2 Receptor alpha Subunit, Interferon-alpha, Interferon-Stimulated Gene Factor 3, Middle Aged, Recombinant Proteins, Clinical trial, Gene Expression Regulation, HBeAg, Immunology, Infectious diseases, Interleukin-2, Medicine, Female, business, CD8, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e45fff313f3e77b83a96cc5ccad309Test
https://doaj.orgTest/article/21b417eb6d294715b19d0a664f3c43a8

10

Serum anti-SERPINE1 antibody as a potential biomarker of acute cerebral infarction

المؤلفون: Shu-Yang Li, Takaki Hiwasa, Bo-Shi Zhang, Tomoo Matsutani, Hirotaka Takizawa, Toshio Machida, Yasuo Iwadate, Seiichiro Mine, Eiichi Kobayashi, Yoichi Yoshida, Masaaki Kubota

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f4273226f29ef41681f3bc45446cbb7Test
https://doaj.orgTest/article/bd1aa44625364c7b85c95ab9f37de29f

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