نتائج البحث - "egfr inhibitors"

1

p85β alters response to EGFR inhibitor in ovarian cancer through p38 MAPK-mediated regulation of DNA repair

المؤلفون: Victor Cy Mak, Ling Rao, Yuan Zhou, Xinran Li, Lydia W.T. Cheung, Sai Wah Tsao

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 7, Pp 718-730 (2021)
Neoplasia (New York, N.Y.)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, medicine.disease_cause, p38 Mitogen-Activated Protein Kinases, PI3K, Mice, 0302 clinical medicine, Epidermal growth factor receptor, RC254-282, EGFR inhibitors, Ovarian Neoplasms, biology, Disease Management, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Class Ia Phosphatidylinositol 3-Kinase, ErbB Receptors, Gene Expression Regulation, Neoplastic, Erlotinib, 030220 oncology & carcinogenesis, Female, Disease Susceptibility, Signal Transduction, medicine.drug, Original article, DNA Copy Number Variations, DNA damage, DNA repair, p38 MAPK, Models, Biological, 03 medical and health sciences, Cell Line, Tumor, DNA Repair Protein, p85 regulatory subunit, medicine, Animals, Humans, Protein Kinase Inhibitors, business.industry, medicine.disease, Disease Models, Animal, 030104 developmental biology, Drug Resistance, Neoplasm, Cancer research, biology.protein, Ovarian cancer, Carcinogenesis, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ecad4c612d528a8bee41b800d44cefTest
http://www.sciencedirect.com/science/article/pii/S1476558621000348Test

2

Computer-aided design of some quinazoline analogues as epidermal growth factor receptor inhibitors

المؤلفون: Sani Uba, Gideon Adamu Shallangwa, Muhammad Tukur Ibrahim, Adamu Uzairu

المصدر: Egyptian Journal of Medical Human Genetics, Vol 22, Iss 1, Pp 1-10 (2021)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1af087fd794219cf5b6475766dbf08dTest
https://doaj.org/article/5de5b9f7ba5e4f62beb860c03bdbe679Test

3

Combining radiomic phenotypes of non-small cell lung cancer with liquid biopsy data may improve prediction of response to EGFR inhibitors

المؤلفون: Peter B. Noël, Taylor A. Black, Despina Kontos, Stephanie S. Yee, Michael J. LaRiviere, Wei-Ting Hwang, Erica L. Carpenter, Charu Aggarwal, Austin L. Chien, Sharyn I. Katz, Eric A. Cohen, Bardia Yousefi, Jeffrey C. Thompson, Thomas H. Buckingham

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Lung Neoplasms, Pharmacogenomic Variants, medicine.medical_treatment, Targeted therapy, Circulating Tumor DNA, Prognostic markers, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Image Processing, Computer-Assisted, Epidermal growth factor receptor, EGFR inhibitors, Aged, 80 and over, Multidisciplinary, biology, Middle Aged, Primary tumor, ErbB Receptors, Phenotype, 030220 oncology & carcinogenesis, Medicine, Female, medicine.medical_specialty, Science, Antineoplastic Agents, Article, 03 medical and health sciences, Internal medicine, medicine, Humans, Liquid biopsy, Lung cancer, Aged, Retrospective Studies, Performance status, business.industry, Liquid Biopsy, Retrospective cohort study, Genes, erbB-1, medicine.disease, 030104 developmental biology, biology.protein, Feasibility Studies, business, Tomography, X-Ray Computed, Non-small-cell lung cancer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77fb54587f2a502c5ce0e6b19afde6b8Test
https://doaj.org/article/2bc9f76cb0c2446eb992e36476f5b7bfTest

4

Foxq1 promotes metastasis of nasopharyngeal carcinoma by inducing vasculogenic mimicry via the EGFR signaling pathway

المؤلفون: Xuemin Ma, Yunfan Luo, Xiaoxiao Yu, Xiang-Ping Li, Juan Lu, Jie Wang, Fan Wang, Xiaohong Peng, Xiong Liu

المصدر: Cell Death and Disease, Vol 12, Iss 5, Pp 1-16 (2021)
Cell Death & Disease

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Immunology, Article, Metastasis, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Drug Delivery Systems, medicine, Nimotuzumab, Humans, Vasculogenic mimicry, Neoplasm Metastasis, Head and neck cancer, EGFR inhibitors, Nasopharyngeal Carcinoma, QH573-671, business.industry, Promoter, Forkhead Transcription Factors, Nasopharyngeal Neoplasms, Cell Biology, medicine.disease, ErbB Receptors, stomatognathic diseases, 030104 developmental biology, Nasopharyngeal carcinoma, 030220 oncology & carcinogenesis, Drug delivery, Cancer research, Erlotinib, business, Cytology, Tumour angiogenesis, medicine.drug, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4635294b85579aef868158d2f41a73bTest
https://doaj.org/article/3c91e31f98d64886a99973a8e48f9875Test

5

Single-cell transcriptional changes associated with drug tolerance and response to combination therapies in cancer

المؤلفون: Alexandra E. Rader, Carlota Rubio-Perez, Maxim V. Frolov, Mary Pasquinelli, Majd M. Ariss, Ryan D. Conrardy, Abul B. M. M. K. Islam, Alexa M. Gajda, Lawrence Eric Feldman, Cammille C. Go, Stefan J. Green, Alexandre Ferro Aissa, Elizaveta V. Benevolenskaya, Nuria Lopez-Bigas, Klara Valyi-Nagy

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-25 (2021)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Epithelial-Mesenchymal Transition, Cancer therapy, Cell Survival, Science, General Physics and Astronomy, Antineoplastic Agents, Drug resistance, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Receptor tyrosine kinase, Gene regulatory networks, 03 medical and health sciences, 0302 clinical medicine, Drug tolerance, Cell Line, Tumor, Neoplasms, Drug Discovery, medicine, Humans, Cancer models, Protein Kinase Inhibitors, EGFR inhibitors, Multidisciplinary, Crizotinib, Drug discovery, Receptor Protein-Tyrosine Kinases, Drug Tolerance, U937 Cells, General Chemistry, respiratory tract diseases, ErbB Receptors, Gene Expression Regulation, Neoplastic, Drug Combinations, Cholesterol, 030104 developmental biology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Mutation, Cancer research, biology.protein, Heterografts, Vesicle-mediated transport, Tyrosine kinase, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5567cf379b66251833dd58cf46aa6c95Test
https://doaj.org/article/07bdc3f7e13d4e018edb5f1887d9c903Test

6

Toward developing a metastatic breast cancer treatment strategy that incorporates history of response to previous treatments

المؤلفون: Aleksandra Olow, Denise M. Wolf, Laura van 't Veer

المصدر: BMC Cancer, Vol 21, Iss 1, Pp 1-12 (2021)
BMC cancer, vol 21, iss 1
BMC Cancer

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, Resistance, Drug Resistance, Datasets as Topic, Drug Screening Assays, 0302 clinical medicine, Software Design, Surgical oncology, Ductal, Cluster Analysis, Data Mining, Medicine, Breast, Cancer, media_common, EGFR inhibitors, screening and diagnosis, Tumor, Drug Substitution, Carcinoma, Ductal, Breast, Disease Management, Metastatic breast cancer, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Combined Modality Therapy, Neoadjuvant Therapy, Progression-Free Survival, Detection, Exact test, Treatment Outcome, 5.1 Pharmaceuticals, 6.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Public Health and Health Services, Female, Development of treatments and therapeutic interventions, Algorithms, Research Article, Drug, medicine.medical_specialty, media_common.quotation_subject, Clinical Decision-Making, Oncology and Carcinogenesis, Aurora A kinase, Breast Neoplasms, Antineoplastic Agents, lcsh:RC254-282, Cell Line, 03 medical and health sciences, Breast cancer, Recommendation algorithm, Clinical Research, Cell Line, Tumor, Internal medicine, Breast Cancer, Genetics, Humans, Oncology & Carcinogenesis, Salvage Therapy, Internet, business.industry, Carcinoma, Evaluation of treatments and therapeutic interventions, Antitumor, Odds ratio, medicine.disease, 4.1 Discovery and preclinical testing of markers and technologies, 030104 developmental biology, Drug Resistance, Neoplasm, Quality of Life, Neoplasm, Drug Screening Assays, Antitumor, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa5fec2928fa85e102749dfc44f9b3b7Test
https://doaj.org/article/faeb29cb14ea49379fa6e3a5193643a6Test

7

Musashi-2 (MSI2) regulates epidermal growth factor receptor (EGFR) expression and response to EGFR inhibitors in EGFR-mutated non-small cell lung cancer (NSCLC)

المصدر: Oncogenesis, Vol 10, Iss 3, Pp 1-14 (2021)
Oncogenesis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3f337bb99129d6a76a8fd9939b769aTest
https://doaj.org/article/2ede848ef5274440b27190aa152d7cbeTest

8

Tackling Drug Resistance in EGFR Exon 20 Insertion Mutant Lung Cancer

المؤلفون: Christopher P Wilding, Simon Vyse, Andrew D. Jenks, Paul H. Huang, Amani Arthur, Laura Pacini

المصدر: Pharmacogenomics and Personalized Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b96bc89a4d05a651319d4dd2fa6b5f7Test
http://europepmc.org/articles/PMC7955704Test

9

Computational Probing the Methylation Sites Related to EGFR Inhibitor-Responsive Genes

المؤلفون: Yongcui Wang, Shilong Chen, Rui Yuan

المصدر: Biomolecules, Vol 11, Iss 1042, p 1042 (2021)
Biomolecules
Volume 11
Issue 7

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cba5a575ab56b45e4403f8bb2231a231Test
https://www.mdpi.com/2218-273X/11/7/1042Test

10

Improving the Efficacy of EGFR Inhibitors by Topical Treatment of Cutaneous Squamous Cell Carcinoma with miR-634 Ointment

المؤلفون: Hidetoshi Hamamoto, Kyoko Fujiwara, Jun Inoue, Katsunori Kobayashi, Johji Inazawa

المصدر: Molecular Therapy: Oncolytics, Vol 19, Iss, Pp 294-307 (2020)
Molecular Therapy Oncolytics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77ed056dd891a4bd0dcd21dbc45991f0Test
http://www.sciencedirect.com/science/article/pii/S2372770520301601Test

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