يعرض 1 - 10 نتائج من 163 نتيجة بحث عن '"MTOR Inhibitors"', وقت الاستعلام: 0.80s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Designing of target‐specific N‐substituted tetrahydroquinoline derivatives as potent mTOR inhibitors via integrated structure‐guided computational approaches.

    المؤلفون: Shaw, Suman1 (AUTHOR), Dey, Rajdeep1 (AUTHOR), Bhatt, Hardik1 (AUTHOR), Patel, Bhumika1 (AUTHOR), Patel, Saumya2 (AUTHOR), Dixit, Nandan2 (AUTHOR), Chaube, Udit1 (AUTHOR) uditchoube@gmail.com

    المصدر: ChemistrySelect. Feb2024, Vol. 9 Issue 7, p1-15. 15p.

    مصطلحات موضوعية: *MTOR inhibitors, *MTOR protein, *MOLECULAR dynamics, *QSAR models, *LUNG cancer


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  2. 2
    دورية أكاديمية
    Seizure reduction in TSC2‐mutant mouse model by an mTOR catalytic inhibitor.

    المؤلفون: Dhamne, Sameer C.1 (AUTHOR), Modi, Meera E.1 (AUTHOR), Gray, Audrey2 (AUTHOR), Bonazzi, Simone2 (AUTHOR), Craig, Lucas2 (AUTHOR), Bainbridge, Elizabeth1 (AUTHOR), Lalani, Lahin1 (AUTHOR), Super, Chloe E.1 (AUTHOR), Schaeffer, Samantha1 (AUTHOR), Capre, Ketthsy2 (AUTHOR), Lubicka, Danuta2 (AUTHOR), Liang, Guiqing2 (AUTHOR), Burdette, Doug2 (AUTHOR), McTighe, Stephanie M.2 (AUTHOR), Gurnani, Sarika1 (AUTHOR), Vermudez, Sheryl Anne D.1 (AUTHOR), Curtis, Daniel2 (AUTHOR), Wilson, Christopher J.2 (AUTHOR), Hameed, Mustafa Q.1 (AUTHOR), D'Amore, Angelica1 (AUTHOR)

    المصدر: Annals of Clinical & Translational Neurology. Oct2023, Vol. 10 Issue 10, p1790-1801. 12p.

    مصطلحات موضوعية: *MTOR inhibitors, *LABORATORY mice, *TUBEROUS sclerosis, *ANIMAL disease models, *RAPAMYCIN, *SEIZURES (Medicine), *VIMPAT

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  3. 3
    دورية أكاديمية
    Unbiased evaluation of rapamycin's specificity as an mTOR inhibitor.

    المؤلفون: Artoni, Filippo1,2 (AUTHOR), Grützmacher, Nina1 (AUTHOR), Demetriades, Constantinos1,2,3 (AUTHOR) demetriades@age.mpg.de

    المصدر: Aging Cell. Aug2023, Vol. 22 Issue 8, p1-15. 15p.

    مصطلحات موضوعية: *RAPAMYCIN, *MTOR inhibitors, *MACROLIDE antibiotics, *ANTINEOPLASTIC agents, *IMMUNOSUPPRESSIVE agents

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  4. 4
    دورية أكاديمية
    The use of mTOR inhibitors for the treatment of kaposiform hemangioendothelioma. A systematic review.

    المؤلفون: Maza-Morales, Mariana1, Valdés-Loperena, Sofía1, Carola Durán-McKinster, Lourdes1, Teresa García-Romero, María1 teregarro@gmail.com

    المصدر: Pediatric Dermatology. May/Jun2023, Vol. 40 Issue 3, p440-445. 6p.

    مصطلحات موضوعية: *MTOR inhibitors, *DUCTUS arteriosus, *LIVER failure, *HEART failure, *GIANT cell tumors, *THERAPEUTICS, *VINCRISTINE


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  5. 5
    دورية أكاديمية
    Analysis of current data on the use of topical mTOR inhibitors in the treatment of facial angiofibromas in tuberous sclerosis complex—An update.

    المؤلفون: Balestri, Riccardo1 (AUTHOR), Rizzoli, Laura1 (AUTHOR), Pedrolli, Annalisa2 (AUTHOR), Urru, Silvana Anna Maria3 (AUTHOR), Rech, Giulia1 (AUTHOR), Neri, Iria4 (AUTHOR), Girardelli, Carlo R.1 (AUTHOR), Magnano, Michela1 (AUTHOR) michela.magnano@gmail.com

    المصدر: Journal of the European Academy of Dermatology & Venereology. Mar2023, Vol. 37 Issue 3, p474-487. 14p.

    مصطلحات موضوعية: *TUBEROUS sclerosis, *MTOR inhibitors, *DATA analysis, *RAPAMYCIN

    مصطلحات جغرافية: EUROPE


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  6. 6
    دورية أكاديمية
    Searching for new mTOR kinase inhibitors: Analysis of binding sites and validation of docking protocols.

    المؤلفون: Stary, Dorota1,2,3 (AUTHOR), Nepovimova, Eugenie2 (AUTHOR) eugenie.nepovimova@uhk.cz, Kuca, Kamil2 (AUTHOR), Bajda, Marek1,2 (AUTHOR) marek.bajda@uj.edu.pl

    المصدر: Chemical Biology & Drug Design. Jan2023, Vol. 101 Issue 1, p103-119. 17p.

    مصطلحات موضوعية: *BINDING site assay, *MTOR inhibitors, *KINASE inhibitors, *AMINO acid residues, *BIOACTIVE compounds


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  7. 7
    دورية أكاديمية
    Efficacy of everolimus‐based therapy in advanced triple‐positive breast cancer: Experience from three cancer centers in China.

    المؤلفون: Tan, Yujing, Jiang, Hanfang, Ma, Fei, Wang, Jiayu, Zhang, Pin, Li, Qing, Tian, Xinzhu, Xu, Binghe, Zhao, Weihong, Fan, Ying

    المصدر: Thoracic Cancer; Dec2023, Vol. 14 Issue 34, p3397-3405, 9p

    مصطلحات موضوعية: DRUG efficacy, RESEARCH, CONFIDENCE intervals, CLINICAL trials, CANCER chemotherapy, TRASTUZUMAB, METASTASIS, ANTINEOPLASTIC agents, MTOR inhibitors, EVEROLIMUS, MEDICAL records, CHI-squared test, RESEARCH funding, PROGRESSION-free survival, BREAST tumors, PHARMACODYNAMICS

    مصطلحات جغرافية: CHINA

    النص الكامل

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  8. 8
    دورية أكاديمية
    Combined treatment with crizotinib and temsirolimus is an effective strategy in mantle cell lymphoma and can overcome acquired resistance to temsirolimus.

    المؤلفون: Moosburner, Marie, Alibegovic, Lamija, Hasselmann, Korbinian, Gaiderov, Anton, Hildebrand, Johannes, Philippou‐Massier, Julia, Blum, Helmut, Fischer, Luca, Dreyling, Martin, Silkenstedt, Elisabeth

    المصدر: Hematological Oncology; Dec2023, Vol. 41 Issue 5, p858-868, 11p

    مصطلحات موضوعية: MANTLE cell lymphoma, CRIZOTINIB, CELL lines, DRUG resistance, MTOR inhibitors


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  9. 9
    دورية أكاديمية
    Loss of ATOH1 in Pit Cell Drives Stemness and Progression of Gastric Adenocarcinoma by Activating AKT/mTOR Signaling through GAS1.

    المؤلفون: Zhong, Qing, Wang, Hua‐Gen, Yang, Ji‐Hong, Tu, Ru‐Hong, Li, An‐Yao, Zeng, Gui‐Rong, Zheng, Qiao‐Ling, Yu Liu, Zhi‐, Shang‐Guan, Zhi‐Xin, Bo Huang, Xiao‐, Huang, Qiang, Li, Yi‐Fan, Zheng, Hua‐Long, Lin, Guang‐Tan, Huang, Ze‐Ning, Xu, Kai‐Xiang, Qiu, Wen‐Wu, Jiang, Mei‐Chen, Zhao, Ya‐Jun, Lin, Jian‐Xian

    المصدر: Advanced Science; 11/14/2023, Vol. 10 Issue 32, p1-17, 17p

    مصطلحات موضوعية: CANCER stem cells, ADENOCARCINOMA, DRUG resistance in cancer cells, MTOR inhibitors, ANIMAL models in research

    النص الكامل

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  10. 10
    دورية أكاديمية
    Paclitaxel promotes mTOR signaling‐mediated apoptosis in esophageal cancer cells by targeting MUC20.

    المؤلفون: Li, Meng, Feng, Zhen, Han, Rui, Hu, Benchuang, Zhang, Renfeng, Wang, Hui

    المصدر: Thoracic Cancer; Nov2023, Vol. 14 Issue 31, p3089-3096, 8p

    مصطلحات موضوعية: PROTEIN kinases, IN vitro studies, REVERSE transcriptase polymerase chain reaction, FLOW cytometry, BIOLOGICAL models, IN vivo studies, WESTERN immunoblotting, ANIMAL experimentation, APOPTOSIS, MTOR inhibitors, CELLULAR signal transduction, CELL survival, COMPARATIVE studies, GLYCOPROTEINS, RESEARCH funding, DESCRIPTIVE statistics, PACLITAXEL, CELL lines, TUMOR markers, ESOPHAGEAL tumors, MICE, PHARMACODYNAMICS

    النص الكامل

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