دورية أكاديمية
Clinimetrics of the cognitive section of the Italian ALS Cognitive Behavioral Screen (ALS-CBSTM)
| العنوان: | Clinimetrics of the cognitive section of the Italian ALS Cognitive Behavioral Screen (ALS-CBSTM) |
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| المؤلفون: | Edoardo Nicolò Aiello, Lucia Catherine Greco, Antonino La Tona, Federica Solca, Silvia Torre, Laura Carelli, Debora Pain, Alice Radici, Andrea Lizio, Jacopo Casiraghi, Federica Cerri, Agostino Brugnera, Angelo Compare, Susan Woolley, Jennifer Murphy, Lucio Tremolizzo, Ildebrando Appollonio, Federico Verde, Vincenzo Silani, Nicola Ticozzi, Christian Lunetta, Valeria Ada Sansone, Barbara Poletti |
| المساهمون: | Aiello, E, Catherine Greco, L, La Tona, A, Solca, F, Torre, S, Carelli, L, Pain, D, Radici, A, Lizio, A, Casiraghi, J, Cerri, F, Brugnera, A, Compare, A, Woolley, S, Murphy, J, Tremolizzo, L, Appollonio, I, Verde, F, Silani, V, Ticozzi, N, Lunetta, C, Ada Sansone, V, Poletti, B |
| بيانات النشر: | Springer - Verlag Italia Srl IT |
| سنة النشر: | 2023 |
| المجموعة: | Università degli Studi di Milano-Bicocca: BOA (Bicocca Open Archive) |
| مصطلحات موضوعية: | ALS Cognitive Behavioral Screen, Amyotrophic lateral sclerosi, Clinimetric, Cognitive screening, Frontotemporal degeneration, Neuropsychology |
| الوصف: | Background: The present study aimed at (1) providing further validity and reliability evidence for the Italian version of the cognitive section of the ALS Cognitive Behavioral Screen (ALS-CBSTM) and (2) testing its diagnostics within an Italian ALS cohort, as well as at (3) exploring its capability to discriminate patients from healthy controls (HCs). Methods: N = 293 non-demented ALS patients were administered the cognitive sections of the ALS-CBSTM and Edinburgh Cognitive and Behavioural ALS Screen (ECAS). N = 96 HCs demographically matched with N = 96 patients were also administered the cognitive section of the ALS-CBSTM. In patients, factorial and construct validity, internal reliability, and diagnostics against a defective score on the cognitive section of the ECAS were tested. Case–control discrimination was assessed via a logistic regression. Results: ALS-CBSTM cognitive subscales were underpinned by a simple, unidimensional structure, internally reliable (McDonald’s ω = 0.74), and mostly related with ECAS executive and fluency scores (rs = 0.54–0.71). Both raw and age- and education-adjusted scores on the cognitive section of the ALS-CBSTM accurately detected ECAS-defined cognitive impairment (AUC = 0.80 and.88, respectively), yielding optimal error-based, information-based and unitary diagnostics. A cut-off of < 15.374 was identified on adjusted scores. The test was able to discriminate patients from HCs (p < 0.001). Discussion: The cognitive section of the Italian ALS-CBSTM is a valid, reliable, and diagnostically sound ALS-specific screener for detecting frontotemporal, executive-/attentive-based cognitive inefficiency in non-demented ALS patients, being also able to discriminate them from normotypical individuals. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | STAMPA |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/36547779; info:eu-repo/semantics/altIdentifier/wos/WOS:000903183400001; volume:44; issue:4; firstpage:1243; lastpage:1249; numberofpages:7; journal:NEUROLOGICAL SCIENCES; https://hdl.handle.net/10281/400231Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85144741737 |
| DOI: | 10.1007/s10072-022-06569-9 |
| الإتاحة: | https://doi.org/10.1007/s10072-022-06569-9Test https://hdl.handle.net/10281/400231Test |
| رقم الانضمام: | edsbas.8CE567D2 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s10072-022-06569-9 |
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