دورية أكاديمية
Analysis of mortality metrics associated with a comprehensive range of disorders in Denmark, 2000 to 2018: A population-based cohort study
| العنوان: | Analysis of mortality metrics associated with a comprehensive range of disorders in Denmark, 2000 to 2018: A population-based cohort study |
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| المؤلفون: | Plana-Ripoll, Oleguer, Dreier, Julie W., Momen, Natalie C., Prior, Anders, Weye, Nanna, Mortensen, Preben Bo, Pedersen, Carsten B., Iburg, Kim Moesgaard, Christensen, Maria Klitgaard, Laursen, Thomas Munk, Agerbo, Esben, Pedersen, Marianne G., Brandt, Jørgen, Frohn, Lise Marie, Geels, Camilla, Christensen, Jesper H., McGrath, John J. |
| المصدر: | e1004023 ; PLoS Medicine ; 19 ; 6 |
| بيانات النشر: | PLoS |
| سنة النشر: | 2022 |
| المجموعة: | University of Bergen: Bergen Open Research Archive (BORA-UiB) |
| الوصف: | Background: The provision of different types of mortality metrics (e.g., mortality rate ratios [MRRs] and life expectancy) allows the research community to access a more informative set of health metrics. The aim of this study was to provide a panel of mortality metrics associated with a comprehensive range of disorders and to design a web page to visualize all results. Methods and findings: In a population-based cohort of all 7,378,598 persons living in Denmark at some point between 2000 and 2018, we identified individuals diagnosed at hospitals with 1,803 specific categories of disorders through the International Classification of Diseases-10th Revision (ICD-10) in the National Patient Register. Information on date and cause of death was obtained from the Registry of Causes of Death. For each of the disorders, a panel of epidemiological and mortality metrics was estimated, including incidence rates, age-of-onset distributions, MRRs, and differences in life expectancy (estimated as life years lost [LYLs]). Additionally, we examined models that adjusted for measures of air pollution to explore potential associations with MRRs. We focus on 39 general medical conditions to simplify the presentation of results, which cover 10 broad categories: circulatory, endocrine, pulmonary, gastrointestinal, urogenital, musculoskeletal, hematologic, mental, and neurologic conditions and cancer. A total of 3,676,694 males and 3,701,904 females were followed up for 101.7 million person-years. During the 19-year follow-up period, 1,034,273 persons (14.0%) died. For 37 of the 39 selected medical conditions, mortality rates were larger and life expectancy shorter compared to the Danish general population. For these 37 disorders, MRRs ranged from 1.09 (95% confidence interval [CI]: 1.09 to 1.10) for vision problems to 7.85 (7.77 to 7.93) for chronic liver disease, while LYLs ranged from 0.31 (0.14 to 0.47) years (approximately 16 weeks) for allergy to 17.05 (16.95 to 17.15) years for chronic liver disease. Adjustment for air ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1548-7091 |
| العلاقة: | urn:issn:1548-7091; https://hdl.handle.net/11250/3033606Test; https://doi.org/10.1371/journal.pmed.1004023Test; cristin:2053771; PLoS Medicine. 2022, 19 (6), e1004023. |
| DOI: | 10.1371/journal.pmed.1004023 |
| الإتاحة: | https://doi.org/10.1371/journal.pmed.1004023Test https://hdl.handle.net/11250/3033606Test |
| حقوق: | Navngivelse 4.0 Internasjonal ; http://creativecommons.org/licenses/by/4.0/deed.noTest ; Copyright the authors 2022 |
| رقم الانضمام: | edsbas.72EB3B6B |
| قاعدة البيانات: | BASE |
| تدمد: | 15487091 |
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| DOI: | 10.1371/journal.pmed.1004023 |