المؤلفون: Wolf-Karsten Hofmann, Arwin Mehralivand, Laurenz Steiner, Nanni Schmitt, Ahmed Jawhar, Cleo-Aron Weis, Stefanie Uhlig, Justine Danner, Vladimir Riabov, Ali Darwich, Qingyu Xu, Julia Obländer, Eva Altrock, Tobias Boch, Nadine Weimer, Florian Nolte, Antje Knaflic, Mohamad Jawhar, Alexander Streuer, Verena Haselmann, Daniel Nowak, Johann-Christoph Jann, Verena Nowak, Alexander Marx, Georgia Metzgeroth, Johanna Flach, Iris Palme

المصدر: Leukemia

مصطلحات موضوعية: Oncology, Agonist, Male, Cancer Research, medicine.medical_specialty, medicine.drug_class, Eltrombopag, Apoptosis, Disease, Mice, SCID, Benzoates, Article, chemistry.chemical_compound, Mice, Mice, Inbred NOD, Internal medicine, hemic and lymphatic diseases, medicine, Tumor Cells, Cultured, Animals, Humans, Thrombopoiesis, Cancer models, Aged, Cell Proliferation, Thrombopoietin receptor, Aged, 80 and over, business.industry, Myelodysplastic syndromes, Hematology, Middle Aged, medicine.disease, Prognosis, Xenograft Model Antitumor Assays, Clinical trial, medicine.anatomical_structure, Hydrazines, chemistry, Preclinical research, Myelodysplastic Syndromes, Pyrazoles, Female, Bone marrow, business, Myelodysplastic syndrome

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9748a1e6c1fc1292c3557204eb8226a6Test
http://europepmc.org/articles/PMC8727300Test

المؤلفون: Wangta Liu, Stephen Chu-Sung Hu, Tsung-Chen Chi, Yi-Hua Chen, Chih-Jen Huang, Ya-Ching Hsieh, Yen-Yun Wang, Yuk-Kwan Chen, Fang-Yu Tsai, Ya-Wen Chen, Shyng-Shiou F. Yuan, Shih Sheng Jiang, Ruei-Nian Li, Steven Lo

المصدر: Oncogene

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, Receptors, CXCR4, Double-strand DNA breaks, Core Binding Factor Alpha 1 Subunit, Mice, SCID, Radiation Tolerance, Article, Metastasis, 03 medical and health sciences, Mice, 0302 clinical medicine, DNA repair complex, Cell Movement, Mice, Inbred NOD, Radioresistance, Cell Line, Tumor, Genetics, medicine, Animals, Humans, Molecular Biology, Protein kinase B, Zebrafish, Cell Proliferation, Nuclease, MRE11 Homologue Protein, Deoxyribonucleases, biology, Cell growth, Oral cancer, Cancer, medicine.disease, Prognosis, Survival Rate, enzymes and coenzymes (carbohydrates), 030104 developmental biology, DNA Repair Enzymes, 030220 oncology & carcinogenesis, Rad50, Cancer research, biology.protein, Hepatocyte Nuclear Factor 3-beta, Heterografts, Female, Mouth Neoplasms, Proto-Oncogene Proteins c-akt, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e2677d17138be0a83de27104568778Test
http://europepmc.org/articles/PMC8134045Test

المؤلفون: Yan Tong, Silpa Gampala, Ellie Rad, Ren Yuan Bai, Olivia Babb, Emily Hulsey, Fenil Shah, Chi Zhang, Steven D. Rhodes, Verena Staedtke, Randall Wireman, Brian L. Calver, Mark R. Kelley, Michelle Grimard, M. Reza Saadatzadeh, Abbi Smith, D. Wade Clapp, Andrew R. Tee, Karen E. Pollok, Melissa L. Fishel

المصدر: British Journal of Cancer

مصطلحات موضوعية: Male, STAT3 Transcription Factor, Cancer Research, Adolescent, Apoptosis, Mice, SCID, Article, Malignant transformation, Paediatric cancer, 03 medical and health sciences, Mice, 0302 clinical medicine, Western blot, In vivo, Mice, Inbred NOD, Biomarkers, Tumor, DNA-(Apurinic or Apyrimidinic Site) Lyase, Tumor Cells, Cultured, Medicine, Animals, Humans, STAT3, 030304 developmental biology, Cell Proliferation, 0303 health sciences, medicine.diagnostic_test, biology, business.industry, Translation (biology), Sarcoma, medicine.disease, Prognosis, Xenograft Model Antitumor Assays, In vitro, Gene Expression Regulation, Neoplastic, Oncology, Neurofibrosarcoma, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Female, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec69838060868f6ccae17ccdf078f1f2Test
http://europepmc.org/articles/PMC8076291Test

المؤلفون: Samuel Achilefu, Katherine Wasden, Abdel Kareem Azab, Justin King, John F. DiPersio, Ravi Vij, Jennifer Sun, Julie O'Neal, Nicole Guenthner, Kinan Alhallak, Daniel Kohnen, Barbara Muz

المصدر: Leukemia

مصطلحات موضوعية: Cancer Research, Lymphoma, medicine.drug_class, medicine.medical_treatment, T cell, T-Lymphocytes, T cells, Myeloma, Apoptosis, Mice, SCID, Monoclonal antibody, Article, Mice, Cancer immunotherapy, Antigen, In vivo, Antigens, Neoplasm, Mice, Inbred NOD, medicine, Tumor Cells, Cultured, Animals, Humans, Cell Proliferation, business.industry, Antibodies, Monoclonal, Hematology, Immunotherapy, Xenograft Model Antitumor Assays, medicine.anatomical_structure, Oncology, Tumor Escape, Cancer cell, Cancer research, Nanoparticles, Female, business, Multiple Myeloma, Biotechnology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0002602fe729d7105d9310f78aa6c586Test
http://europepmc.org/articles/PMC8292428Test

المؤلفون: Nancy Nguyen, Ze'ev Ronai, Sharmila Mallya, Roberta Buono, J. Scott Lee, Anthony B. Pinkerton, Boyang Li, Amos Fung, David A. Fruman, Michael R. Jackson, Beth Walters, Lee-or Herzog, Robert J. Schneider, Honyin Chiu

المصدر: British Journal of Cancer
British journal of cancer, vol 124, iss 6

مصطلحات موضوعية: Cancer Research, Lymphoma, Drug Resistance, Apoptosis, Mice, SCID, Quinolones, chemistry.chemical_compound, Eukaryotic initiation factor 4F, Mice, 0302 clinical medicine, Mice, Inbred NOD, hemic and lymphatic diseases, Antineoplastic Combined Chemotherapy Protocols, Tumor Cells, Cultured, Molecular Targeted Therapy, Cancer, Sulfonamides, Cultured, Molecular medicine, Kinase, B-cell lymphoma, Heterocyclic, Hematology, Tumor Cells, Oncology, 030220 oncology & carcinogenesis, Public Health and Health Services, Female, Lymphoma, B-Cell, Lactams, Oncology and Carcinogenesis, SCID, Article, 03 medical and health sciences, Bridged Bicyclo Compounds, Eukaryotic translation, Rare Diseases, medicine, Initiation factor, Animals, Humans, Oncology & Carcinogenesis, PI3K/AKT/mTOR pathway, Cell Proliferation, Venetoclax, B-Cell, medicine.disease, Bridged Bicyclo Compounds, Heterocyclic, Xenograft Model Antitumor Assays, Eukaryotic Initiation Factor-4E, chemistry, Drug Resistance, Neoplasm, Cancer research, Inbred NOD, Neoplasm, Mantle cell lymphoma

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e149b3e92e1cf9b4908b4bc85b95ffTest
http://europepmc.org/articles/PMC7960756Test

المؤلفون: Jaewoo Choi, Sagar Bajpai, Hong Ri Jin, Akihiro Yoshida, Yan Li, J. Alan Diehl, Shuo Qie

المصدر: Oncogene

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Ubiquitylation, Lymphoma, Apoptosis, Mice, SCID, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Genetics, Biomarkers, Tumor, Tumor Cells, Cultured, Animals, Humans, Cyclin D3, Molecular Biology, Cyclin, Cell Proliferation, Regulation of gene expression, biology, Cell growth, F-Box Proteins, Cell Cycle, Cell cycle, Hematopoietic Stem Cells, Burkitt Lymphoma, Xenograft Model Antitumor Assays, Ubiquitin ligase, Gene Expression Regulation, Neoplastic, Mice, Inbred C57BL, 030104 developmental biology, Proteasome, 030220 oncology & carcinogenesis, Proteolysis, biology.protein, Cancer research, Protein stabilization

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1676397e6411136a24e208b41d59f13Test
http://europepmc.org/articles/PMC7808939Test

المؤلفون: Zhihua Li, Linda Z. Penn, Benjamin Haibe-Kains, Jonathan J Keats, Joseph Longo, Suzanne Trudel, David W. Andrews, Jonathan D. Licht, Trevor J. Pugh, Emily Branchard, Petr Smirnov, Jenna E. van Leeuwen

المصدر: Leukemia

مصطلحات موضوعية: Cancer Research, Geranylgeranyl pyrophosphate, Mevalonic Acid, Antineoplastic Agents, Apoptosis, Mice, SCID, Plasma cell, Article, Translocation, Genetic, Bortezomib, chemistry.chemical_compound, Mice, Targeted therapies, Polyisoprenyl Phosphates, Mice, Inbred NOD, medicine, Biomarkers, Tumor, Tumor Cells, Cultured, Integrated stress response, Animals, Humans, Fluvastatin, Multiple myeloma, Cell Proliferation, Chromosomes, Human, Pair 14, business.industry, Hematology, medicine.disease, Cancer metabolism, Xenograft Model Antitumor Assays, Gene Expression Regulation, Neoplastic, medicine.anatomical_structure, Oncology, chemistry, Proteasome inhibitor, Cancer research, Female, Mevalonate pathway, Chromosomes, Human, Pair 4, Hydroxymethylglutaryl-CoA Reductase Inhibitors, business, Multiple Myeloma, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a516bd5168c42530f65f8d58e53d28fTest
http://europepmc.org/articles/PMC7359767Test

المؤلفون: Michelle A. Lawson, Jennifer M. Down, Lisa J. Crawford, Dharminder Chauhan, Andrew D Chantry, Claudia Hamilton, Jonathan J. Morgan, Treen C. M. Morris, Krishnaraj Rajalingam, Alexandra E. Irvine, Roisin McAvera, Aswini Krishnan, David Campbell

المصدر: Oncogene
Crawford, L J, Campbell, D C, Morgan, J J, Lawson, M A, Down, J M, Chauhan, D, McAvera, R M, Morris, T C, Hamilton, C, Krishnan, A, Rajalingam, K, Chantry, A D & Irvine, A E 2020, ' The E3 ligase HUWE1 inhibition as a therapeutic strategy to target MYC in Multiple Myeloma ', Oncogene, vol. 39, pp. 5001–5014 . https://doi.org/10.1038/s41388-020-1345-xTest

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Ubiquitylation, Cell Survival, Ubiquitin-Protein Ligases, Myeloma, Antineoplastic Agents, Bone Marrow Cells, Mice, SCID, Article, Proto-Oncogene Proteins c-myc, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Ubiquitin, Mice, Inbred NOD, Cell Line, Tumor, Genetics, medicine, Animals, Humans, RNA, Small Interfering, Molecular Biology, Lenalidomide, Cell Proliferation, Gene knockdown, biology, Oncogene, Cell growth, Tumor Suppressor Proteins, Ubiquitination, Cell Cycle Checkpoints, Ubiquitin ligase, Therapeutic Index, Drug, 030104 developmental biology, medicine.anatomical_structure, chemistry, Proteasome, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Female, RNA Interference, Bone marrow, Growth inhibition, Multiple Myeloma, Oligopeptides

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37220f16bcd269c548b5b079bcc895e5Test
http://europepmc.org/articles/PMC7329634Test

المؤلفون: Sk Kayum Alam, Luke H. Hoeppner, Christina E. Hernandez, Rendong Yang, Farhad Kosari, Anja C. Roden, Li Wang, Yanan Ren

المصدر: British Journal of Cancer

مصطلحات موضوعية: Gene isoform, Male, Cancer Research, Dopamine and cAMP-Regulated Phosphoprotein 32, Lung Neoplasms, MAP Kinase Signaling System, Mice, SCID, Biology, medicine.disease_cause, Article, Small-cell lung cancer, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, medicine, Basic Helix-Loop-Helix Transcription Factors, Animals, Humans, Protein Isoforms, Lung cancer, Protein kinase B, neoplasms, 030304 developmental biology, Cell Proliferation, 0303 health sciences, Cell growth, medicine.disease, Small Cell Lung Carcinoma, humanities, respiratory tract diseases, ASCL1, Neuroendocrine Tumors, Mechanisms of disease, HEK293 Cells, Oncology, Apoptosis, 030220 oncology & carcinogenesis, Cancer research, Heterografts, Female, Carcinogenesis, Proto-Oncogene Proteins c-akt, Immunostaining

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b36db807289ca953ff7f5d76d17c2638Test
http://europepmc.org/articles/PMC7463034Test

المؤلفون: Leal Oburoglu, Niels-Bjarne Woods, Els Mansell

المصدر: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)

مصطلحات موضوعية: Hemangioblasts, Science, Glutamine, Regulator, Stem-cell differentiation, Mice, SCID, Biology, Article, Mice, Pluripotent stem cells, Mice, Inbred NOD, Gene expression, Animals, Humans, Cell Lineage, Cells, Cultured, Cell Proliferation, Multidisciplinary, Haematopoietic stem cells, Cell Differentiation, Hematopoietic Stem Cells, Phenotype, In vitro, Cell biology, Hematopoiesis, Transplantation, Mice, Inbred C57BL, Haematopoiesis, Metabolic pathways, Medicine, Female, Function (biology)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6acc94ffb039022612ab9304cecdc34bTest
http://europepmc.org/articles/PMC8413451Test