التفاصيل البيبلوغرافية
| العنوان: |
Tumor Microenvironment and Immune Effects of Antineoplastic Therapy in Lymphoproliferative Syndromes |
| المؤلفون: |
Tomás Álvaro, Luis de la Cruz-Merino, Fernando Henao-Carrasco, José Luis Villar Rodríguez, David Vicente Baz, Manuel Codes Manuel de Villena, Mariano Provencio |
| بيانات النشر: |
Journal of Biomedicine and Biotechnology |
| سنة النشر: |
2010 |
| المجموعة: |
Hindawi Publishing Corporation |
| مصطلحات موضوعية: |
Immunology |
| الوصف: |
Lymphomas represent a wide group of heterogenic diseases with different biological and clinical behavior. The underlying microenvironment-specific composition seems to play an essential role in this scenario, harboring the ability to develop successful immune responses or, on the contrary, leading to immune evasion and even promotion of tumor growth. Depending on surrounding lymphoid infiltrates, lymphomas may have different prognosis. Moreover, recent evidences have emerged that confer a significant impact of main lymphoma's treatment over microenvironment, with clinical consequences. In this review, we summarize these concepts from a pathological and clinical perspective. Also, the state of the art of lymphoma's anti-idiotype vaccine development is revised, highlighting the situations where this strategy has proven to be successful and eventual clues to obtain better results in the future. |
| نوع الوثيقة: |
review |
| اللغة: |
English |
| العلاقة: |
https://doi.org/10.1155/2010/846872Test |
| DOI: |
10.1155/2010/846872 |
| الإتاحة: |
https://doi.org/10.1155/2010/846872Test |
| حقوق: |
Copyright © 2010 Tomás Álvaro et al. |
| رقم الانضمام: |
edsbas.D0078183 |
| قاعدة البيانات: |
BASE |
