المؤلفون: Yuqi MA, Mei WANG, Xiaonian CAO, Qiang LI, Dingtao WU, Ling DONG, Fengju ZHANG, Yichen HU

المصدر: Shipin gongye ke-ji, Vol 45, Iss 11, Pp 296-306 (2024)

مصطلحات موضوعية: tatary buckwheat, pleurotus eryngii, fermentation, antioxidant activity, chronic alcoholic liver injury, chronic alcoholic gastric mucosal injury, Food processing and manufacture, TP368-456

الوصف: Objective: To investigate the antioxidant activity of fermented tartaty buckwheat extract of Pleurotus eryngii in vitro as well as its protective effect on alcohol-induced liver and gastric mucosa injury in vivo. Methods: The study involved determining the contents of functional components in fermented tartary buckwheat extract and observing its antioxidant capacity. Mice models of chronic alcoholic liver and gastric mucosa injury were established using Lieber-DeCarli liquid feed. The protective effects of fermented tartary buckwheat extract at low and high doses (1.5 g/kg B.W., 3.0 g/kg B.W.) were investigated for both liver and gastric mucosa injury. Results: The extract of fermented buckwheat with Pleurotus eryngii contained more antioxidant components, the contents of polyphenols, flavonoids and triterpenes were 11.40±0.32 mgGAE/g DW, 17.19±0.30 mg RE/g DW and 7.59±0.24 mg/g, respectively. The contents of rutin and quercetin were as follows: 13.55±0.05 and 0.665±0.01 mg/g. The iron reducing antioxidant capacity and DPPH and ABTS+ free radical scavenging efficiency of Tartary buckwheat extract were 16.66±0.65, 33.49±1.26 and 15.68±1.17 μmol Trolox/g DW, respectively. Compared with the model group, both high-dose and low-dose groups significantly reduced malondialdehyde (P

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1002-0306Test

الوصول الحر: https://doaj.org/article/90f61fb5a9c84d44b8cf0d55798432a3Test

المؤلفون: Lang LIU, Zhiyu FANG, Shuangming WANG, Guobin GAO, Bo ZHANG, Yujiao ZHAO, Mengbo ZHU, Zhichao LIU, Jingyu WANG, Jing ZHOU, Yan LI, Mei WANG, Xiaoyan ZHANG, Song ZHOU, Qifeng JIA

المصدر: Meitan kexue jishu, Vol 52, Iss 2, Pp 292-308 (2024)

مصطلحات موضوعية: co2 sequestration, termittent backfilling, backfill carbon fixation, carbon footprint, carbon sequestration, Mining engineering. Metallurgy, TN1-997

الوصف: Under the national “dual carbon” goal, how to reduce the carbon emissions of the coal industry and achieve carbon storage has become an urgent problem to be solved. The coal industry is the producer of high carbon fossil energy and the main carbon emission source provider. In the process of production and consumption, the accumulation of bulk solid waste, the formation of large goaf and a large amount of CO2 emissions are the bottlenecks that restrict the sustainable development and utilization and the green and healthy development of the coal industry. In order to solve the problem of carbon dioxide storage and mine waste consumption, the bulk solid waste disposal, high-value solid waste utilization, CO2 storage and goaf utilization were organically combined, the concept of carbon dioxide backfill was put forward, and three types of dioxide backfill were defined from the perspective of carbon sink capacity assessment. ① The basic theories involved in the transportation process of CO2 filling slurry and mineralization reaction process are analyzed. The mathematical equations for each process and calculation formulas for carbon sequestration amount are provided. The influence of factors such as temperature and humidity on the mineralization reaction mechanism, carbon sequestration amount, and strength of the backfill body are pointed out. ② The carbonation technological approaches, CO2 sequestration capacity of major alkaline industrial solid wastes and enhancing measures of CO2 mineralization are summarized. On this premise, two types of CO2 backfill materials preparation technique based on direct carbonationand or indirect carbonationand are presented, which can fulfill the criterion of mine backfill in fluidity, solidification characteristics and strength. ③ To solve the problem of decomposed CO2 escaping during CO2 backfill, two technical paths of strip roadway paste backfilling and intermittent backfilling behind packed hydraulic support have been proposed. The former sequesters decomposed CO2 by constructing backfilling bodies with multiple through holes in the weak backfilling strip, while the latter uses packed hydraulic support and chain self-filling baffling to construct backfilling strips in longwall goaf to control roof caving and form a CO2 physicochemical storage space. ④ In order to evaluate the carbon balance effect of CO2 backfill, the calculation boundary of carbon footprint and carbon sequestration in CO2 backfill was defined according to the life cycle method, including the stages of raw material mining, transportation, processing, injection, solidification, etc. Then, the carbon footprint and carbon sequestration in the CO2 backfill process were sorted out, and factors such as the source, dosage, loss, and conversion of CO2 were considered. Next, the calculation methods of carbon footprint and carbon sequestration in the processes of raw material transportation, filling slurry preparation, underground injection and filling were given. The research results are expected to reduce the energy consumption and cost of CO2 storage, and have far-reaching significance for green coal mining and sustainable development and utilization.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/0253-2336Test

الوصول الحر: https://doaj.org/article/9754df0a6852401d97db758f5aa96f76Test

المؤلفون: Jun WU, Junting WU, Biwen YANG, Mei WANG, Pei ZHAO, Jingqiu MA, Yue HUANG, Chuanshu HUANG

المصدر: Shipin gongye ke-ji, Vol 45, Iss 3, Pp 31-39 (2024)

مصطلحات موضوعية: deep eutectic solvent, total flavonoids in mulberry leaves, ultrasonic-enzyme-assisted, response surface methodology, antioxidant activity, Food processing and manufacture, TP368-456

الوصف: This study used ultrasound-enzyme-assisted deep eutectic solvents to establish a green and highly efficient total flavonoids extraction process from mulberry leaves. On the basis of the results of single-factor experiments, the extraction amount of total flavonoids was used as the response value, and the Box-Behnken response surface method was used to optimize, and the antioxidative ability of total flavonoids from mulberry leaves on DPPH radicals and ABTS+ radicals was studied. The results showed that when the choline chloride/fructose/alcohol molar ratio was 1:1:3, water content 30%, liquid-solid ratio 40 mL/g, ultrasonic power 360 W, ultrasonic temperature 40 ℃, ultrasonic time 40 min, dosage of enzyme 4%, the extraction amount of total flavonoids from mulberry leaves reached 46.58 mg/g. When the mass concentration of total flavonoids from mulberry leaves was 0.08 mg/mL, the scavenging rate of DPPH radicals was 98.36%. And when the mass concentration of total flavonoids from mulberry leaves was 0.2 mg/mL, the scavenging rate of ABTS+ radicals was 72.12%. Therefore, the ultrasonic-enzyme-assisted deep eutectic solvents method was green and simple to operate, and could effectively improve the extraction yield of total flavonoids from mulberry leaves. This method provided a scientific basis for the development and utilization of mulberry leaf resources.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1002-0306Test

الوصول الحر: https://doaj.org/article/3ccc67f334524f91af093b4c44fa3ef9Test

المؤلفون: Zhongai CHEN, Yangyang GENG, Shan HUANG, Du LÜ, Jianbo TANG, Mei WANG, Debin WANG

المصدر: Shipin gongye ke-ji, Vol 44, Iss 3, Pp 262-268 (2023)

مصطلحات موضوعية: bamboo shoots, cultivars, mineral, amino acids evaluation, principal component analysis, Food processing and manufacture, TP368-456

الوصف: The contents of basic components, amino acids and minerals were analyzed to explore the differences in the main nutritional components for square bamboo shoot, mati bamboo shoot, datou bamboo shoot, ma bamboo shoot and sweet bamboo shoot. First of all, inductively coupled plasma-mass spectrometry (ICP-MS) and amino acid analyzer were used to determine the content of mineral and free amino acid, respectively. Subsequently, amino acid ratio analysis and comprehensive evaluation of principal components were conducted. The results showed that the protein content (3.73 g/100 g), K content (4031.52 mg/kg), Ca content (276.82 mg/kg) of square bamboo shoot and crude fiber content (1.59 g/100 g) of mati bamboo shoot were significantly higher than those of other four varieties. Moreover, the contents of Mg, Fe and Mn in sweet bamboo shoots were higher than in other bamboo shoots up to 153.16 mg/kg, 5.57 mg/kg and 17.46 mg/kg, respectively. Simultaneously, a small amount of Se existed in datou and sweet bamboo shoots. Besides, the content of harmful elements Cr, Pb and Hg were within the allowable range of the state. Therefore, square bamboo shoots could be used as a good source of protein, K as well as Ca and mati bamboo shoots were deemed as a food which was rich in dietary fiber; sweet bamboo shoots could be considered as an excellent source of Fe, while datou and sweet bamboo shoots were regarded as Selenium-rich vegetables. The EAA/TAA and EAA/NEAA of square bamboo shoots reached 0.44 and 0.79, respectively, via the analysis of EAA/TAA (ratio of essential amino acids to total amino acids) and EAA/NEAA (ratio of essential amino acids to non-essential amino acids), which had met the standards required by FAO/WHO reference model for EAA/TAA and EAA/NEAA up to 0.40 and 0.60. At the end, PCA was used to cluster analysis for the 5 species of bamboo shoots. The datou bamboo shoot and mati bamboo shoot clustered into one category, and the other 3 bamboo shoots clustered into one category, respectively. In a word, the nutritional composition analysis of bamboo shoots can provide theoretical support for the further processing of bamboo shoots.

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1002-0306Test

الوصول الحر: https://doaj.org/article/37735c0be041486f8fc972b2ca75c505Test

المؤلفون: Lijuan XU, Yingtai CHEN, Mei WANG

المصدر: Chinese Journal of Lung Cancer, Vol 25, Iss 10, Pp 715-722 (2022)

مصطلحات موضوعية: radiotherapy combined with immunotherapy, efficacy, safety, brain metastases, lung neoplasms, meta-analysis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

الوصف: Background and objective Immunotherapy (IT) is recommended for the treatment of advanced non-small cell lung cancer (NSCLC), while brain radiotherapy (RT) is the mainstream treatment for patients with brain metastases (BM). This study aimed to investigate the efficacy and safety of combined use of RT and IT. Methods The date was limited to May 1, 2022, and literature searches were carried out in CNKI, Wanfang, PubMed, EMBASE and Cochrane databases. Heterogeneity was judged using the I2 test and P value. Publication bias was assessed using a funnel plot. The quality of included studies was assessed using the Newcastle-Ottawa Scale (NOS). Statistical analysis was performed using Stata 16.0 software. Results A total of 17 articles involving 2,636 patients were included. In the comparison of RT+IT group and RT group, no significant difference was found in overall survival (OS) (HR=0.85, 95%CI: 0.52-1.38, I2=73.9%, Pheterogeneity=0.001) and intracranial distance control (DBC) (HR=1.04, 95%CI: 0.55-1.05, I2=80.5%, Pheterogeneity

وصف الملف: electronic resource

العلاقة: http://www.lungca.org/index.php?journal=01&page=article&op=view&path%5B%5D=10.3779%2Fj.issn.1009-3419.2022.101.48Test; https://doaj.org/toc/1009-3419Test; https://doaj.org/toc/1999-6187Test

الوصول الحر: https://doaj.org/article/7788c54c01f34dd4924ef653cb10ad28Test

المؤلفون: Kai YANG, Mujing LIN, Chenlong WANG, Mei WANG

المصدر: Taiyuan Ligong Daxue xuebao, Vol 52, Iss 5, Pp 797-802 (2021)

مصطلحات موضوعية: rock joints, roughness profile index (jrc), discrete point spacing, digital representation, Chemical engineering, TP155-156, Materials of engineering and construction. Mechanics of materials, TA401-492, Technology

الوصف: Rock mass structure surface morphology characteristics have significant inflence on structural plane shear mechanical behavior. Ten BARTON standard contours were taken as the research object for image denoising and digital characterization. The statistical parameters Rp, SF and Z2 of the contours with different discrete point spacing were calculated, and then the roughness JRC of the structural surface was obtained. The rationality of the image processing method was verified by comparing the calculated values of JRC with theoretical ones, and the influence of discrete point spacing was discussed. The results show that the discrete point spacing has a great influence on JRC and statistical parameters, and different parameters have different sensitivities to discrete point spacing. The JRC value calculated by the digital representation method is in good agreement with the real JRC range. This work has a certain reference value for the study of JRC.

وصف الملف: electronic resource

العلاقة: https://tyutjournal.tyut.edu.cn/englishpaper/show-338.htmlTest; https://doaj.org/toc/1007-9432Test

الوصول الحر: https://doaj.org/article/30040038769b4cd7856ba3ed6eeb65e8Test

المؤلفون: Yan GENG, Mei WANG, Zhonghui HAN, Songsong YANG

المصدر: Taiyuan Ligong Daxue xuebao, Vol 52, Iss 2, Pp 204-210 (2021)

مصطلحات موضوعية: pipe-roof pre-construction process method, densely arranged top tube group, pipe jacking spacing, the soil arch between the tube, the soil arch effect, Chemical engineering, TP155-156, Materials of engineering and construction. Mechanics of materials, TA401-492, Technology

الوصف: At present, domestic research on pipe roof pre-construction method mainly relies on construction experience, but has not yet formed an effective theoretical basis. In order to study the influence mechanism of pipe jacking spacing and soil arching effect, the large diameter pipe jacking construction method of pipe curtain preconstruction in Taiyuan Railway Station was taken as the background, according to the theory of soil arching effect, to establish the stress analysis model of soil arch between two pipes with unequal height, derive the strength control formula of apex of arch and arch foot and its applicable conditions, and obtain the calculation equations of pipe jacking distance. With Taiyuan Railway Station tunnel project as an example, the rationality of pipe spacing obtained by the above method was verified. The influence of various parameters of pipe jacking and soil on soil-arch effect was analyzed. It is concluded that with the increase of the angle of adjacent pipe jacking, the arch span is first decreased to the lowest point and then increased. This study has certain reference value for the theoretical research of pipe-roof pre-construction process method in the future.

وصف الملف: electronic resource

العلاقة: https://tyutjournal.tyut.edu.cn/englishpaper/show-136.htmlTest; https://doaj.org/toc/1007-9432Test

الوصول الحر: https://doaj.org/article/d2cf082d30304dd9b11361e097d2ccc9Test

المؤلفون: Xiaolong ZHAO, Li LI, Liangbin LI, Li CHEN, Qingchen WU, Zhiming QIN, Mei WANG, Mingjian GE

المصدر: Chinese Journal of Lung Cancer, Vol 12, Iss 9, Pp 945-950 (2009)

مصطلحات موضوعية: Lung neoplasms, Gene-expression, Lymphatic metastasis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

الوصف: Background and objective With the most recent introduction of microarray technology to biology, it becomes possible to perform comprehensive analysis of gene expression in cancer cell. In this study the laser microdissection technique and cDNA microarray analysis were combined to obtain accurate molecular profiles of lymphatic metastasis in patients with lung squamous cell carcinoma. Methods Primary lung squamous cancer tissues and regional lymph nodes were obtained from 10 patients who underwent complete resection of lung cancer. According to the source of lung cancer cells, the samples were classified into three groups: the primary tumor with lymphatic metastasis (TxN+, n=5), the primary tumor without lymphatic metastasis (TxN-, n=5) and matched tumor cells from metastatic lymph nodes (N+, n=5). Total RNA was extracted from laser microdissected tumor samples. Adequate RNA starting material of mRNA from primary tumor or metastatic nodes were labeled and then hybridized into the same microarray containing 6 000 known, named human genes/ESTs. After scanning, data analysis was performed using GeneSpringTM6.2. Results A total of 37 genes were found to be able to separate TxN+ from TxN-. TxN+ have higher levels of genes concerned with structural protein, signal transducer, chaperone and enzyme. TxN- have higher levels of genes coding for cell cycle regulator, transporter, signal transducer and apoptosis regulator. Interestingly, there were no differentially expressed genes between N+ and TxN+. Conclusion The acquisition of the metastatic phenotype might occur early in the development of lung squamous cancer. We raise the hypothesis that the gene-expression signature described herein is valuable to elucidate the molecular mechanisms regarding lymphatic metastasis and to look for novel therapeutic targets.

وصف الملف: electronic resource

العلاقة: http://www.lungca.org/index.php?journal=01&page=article&op=viewFile&pathTest[]=10.3779%2Fj.issn.1009-3419.2009.09.001&path[]=1093; https://doaj.org/toc/1009-3419Test; https://doaj.org/toc/1999-6187Test

الوصول الحر: https://doaj.org/article/339a0d1256fd47589abd0a26de709b69Test

المؤلفون: Yu⁃chen QIAO, Hong CHANG, Jia⁃mei WANG, Xuan YANG, Na WEI, Ai⁃cong DING

المصدر: Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 23, Iss 4, Pp 310-325 (2023)

مصطلحات موضوعية: lewy body disease, orexins, risk factors, logistic models, Neurology. Diseases of the nervous system, RC346-429

الوصف: Objective To analyze the correlations between plasma orexin⁃A and clinical manifestations of dementia with Lewy bodies (DLB). Methods A total of 51 patients with DLB from Beijing Tiantan hospital, Capital Medical University, and 46 sex, age and education matched controls were conducted from January 2019 to December 2021. Overall cognitive function was assessed by Mini⁃Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA), dementia severity was assessed by Clinical Dementia Rating Scale (CDR), activities of daily living was assessed by Activities of Daily Living Scale (ADL), depression severity was assessed by Hamilton Depression Rating Scale 17 (HAMD⁃17), neuropsychiatric symptoms was assessed by Neuropsychiatric Inventory (NPI), and plasma orexin⁃A level was measured. The univariate and multivariate Logistic regression analyses were used to screen influencing factors for DLB. Pearson and partial correlation analyses were used to explore the correlation between plasma orexin⁃A and core clinical features of DLB. Multivariate linear stepwise regression analysis was used to analyze the linear correlation between plasma orexin⁃A level and neuropsychological tests. Results The scores of MMSE (Z=⁃ 8.387, P=0.000) and MoCA (Z=⁃8.479, P=0.000) in DLB group were significantly lower than those in control group, while the scores of CDR (Z=⁃9.072, P = 0.000), ADL(Z=⁃8.692, P=0.000), HAMD⁃17 (Z=⁃7.568, P=0.000), NPI (Z=⁃8.270, P=0.000) and plasma orexin⁃A level (Z=⁃2.688, P=0.007) were significantly higher than those in control group. Plasma orexin⁃A level in DLB patients with fluctuating cognition (Z=⁃2.172, P=0.030) and with Parkinsonism (Z=⁃1.981, P=0.048) were lower than those without these symptoms, respectively. Logistic regression analysis showed drinking history was a potentially independent protective factor for DLB (OR=0.278, 95%CI:0.095-0.808; P=0.019), while increased plasma orexin⁃A level was an independent risk factor for DLB (OR=6.878, 95%CI:1.241-38.137; P=0.027). Correlation analysis ...

العلاقة: http://www.cjcnn.org/index.php/cjcnn/article/view/2663Test; https://doaj.org/toc/1672-6731Test; https://doaj.org/article/2d0f564ac1d3426fb4e8053d6dc8295aTest

الإتاحة: https://doi.org/10.3969/j.issn.1672Test⁃6731.2023.04.007
https://doaj.org/article/2d0f564ac1d3426fb4e8053d6dc8295aTest

المؤلفون: DONG Xiao-mei, WANG Rui, ZOU Xin-kai

المصدر: Jisuanji kexue, Vol 48, Iss 9, Pp 21-35 (2021)

مصطلحات موضوعية: recommendation algorithm|differential privacy|deep learning|collaborative filtering|matrix decomposition, Computer software, QA76.75-76.765, Technology (General), T1-995

الوصف: In the context of the era of big data,various industries want to train recommendation models based on user behavior data to provide users with accurate recommendations.The common characteristics of the used data are huge amount,carrying sensitive information,and easy to obtain.The recommendation system is sharing users' private data in real time while bringing accurate recommendation and market profit.Differential privacy,as a privacy protection technology,can cleverly solve the problem of privacy leakage in recommendation applications.No matter the attacker has any relevant background knowledge,differential privacy strictly defines privacy protection,and provides quantitative evaluation methods to ensure that the level of privacy protection provided by the data set is comparable.First,the concept of differential privacy and the research on mainstream recommendation algorithms is briefly described.Second,the combined application of differential privacy and recommendation algorithms is analyzed,such as matrix factorization,deep learning recommendation,and collaborative filtering.A large number of comparative experiments have been conducted on recommendation algorithms based on differential privacy technology.Then the application scenarios of the combination of differential privacy and each recommendation algorithm and the remaining problems are discussed.Finally,effective suggestions are put forward for the future development direction of the recommendation algorithm based on differential privacy.

العلاقة: http://www.jsjkx.com/fileup/1002-137X/PDF/1002-137X-2021-9-21.pdfTest; https://doaj.org/toc/1002-137XTest; https://doaj.org/article/8caab9357dbd4a868af39f7101f8e992Test

الإتاحة: https://doi.org/10.11896/jsjkx.201100083Test
https://doaj.org/article/8caab9357dbd4a868af39f7101f8e992Test