التفاصيل البيبلوغرافية
| العنوان: |
儿童肺炎支原体肺炎合并外周血 淋巴细胞计数减少的临床分析. (Chinese) |
| العنوان البديل: |
Clinical features of children with Mycoplasma pneumoniae pneumonia and peripheral lymphocytopenia. (English) |
| المؤلفون: |
彭力, 钟礼立, 黄振, 黎燕, 张兵 |
| المصدر: |
Chinese Journal of Contemporary Pediatrics; Jan2021, Vol. 23 Issue 1, p74-77, 4p |
| مصطلحات موضوعية: |
MYCOPLASMA pneumoniae infections, MYCOPLASMA pneumoniae, LYMPHOCYTE count, LACTATE dehydrogenase, LYMPHOPENIA, TOOTH erosion |
| الملخص (بالإنجليزية): |
Objective To study the clinical features of children with Mycoplasma pneumoniae pneumonia (MPP) and peripheral lymphocytopenia. Methods A total of 310 MPP children who were hospitalized and underwent bronchoalveolar lavage from June 2018 to June 2019 were enrolled and divided into two groups: simple MPP group with 241 children (without peripheral lymphocytopenia) and MPP + peripheral lymphocytopenia group with 69 children. The two groups were compared in terms of clinical data and treatment outcome. Results Compared with the simple MPP group, the MPP + peripheral lymphocytopenia group had significantly longer duration of fever and length of hospital stay and significant increases in C-reactive protein, lactate dehydrogenase, and Mycoplasma pneumoniae DNA copies in bronchoalveolar lavage fluid (P<0.05). Compared with the simple MPP group, the MPP + peripheral lymphocytopenia group had significantly higher incidence rates of intrapulmonary consolidation, extrapulmonary complications, and serious lesions under bronchoscopy (erosion or sputum bolt) and a significantly higher proportion of patients with severe MPP (P<0.05). Conclusions Children with MPP and peripheral lymphocytopenia tend to have more severe immunologic injury. Peripheral blood lymphocyte count may be used to evaluate the severity of MPP. [ABSTRACT FROM AUTHOR] |
| Abstract (Chinese): |
目的 探讨儿童肺炎支原体肺炎（MPP）合并外周血淋巴细胞计数减少的临床特征。方法 纳 入2018 年6 月至2019 年6 月进行支气管肺泡灌洗的MPP 住院患儿310 例作为研究对象，包括单纯MPP 患儿 241 例（未合并外周血淋巴细胞减少），MPP 合并外周血淋巴细胞减少患儿69 例，比较两组患儿临床资料及治 疗转归。结果 与单纯MPP 组比较，MPP 合并淋巴细胞计数减少组的热程和住院时间均较长，C 反应蛋白、乳 酸脱氢酶、支气管肺泡灌洗液中肺炎支原体DNA 拷贝数值均显著升高（P<0.05）。MPP 合并淋巴细胞计数减少 组肺实变、肺外并发症、支气管镜下严重病变（糜烂/痰栓）及重症MPP 病例的发生率均明显高于单纯MPP 组 （P<0.05）。结论 MPP 合并外周血淋巴细胞计数减少患儿存在更严重的免疫损伤;外周血淋巴细胞数量可在 一定程度上反映MPP 的严重程度. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
