دورية أكاديمية
The Association of MMP7 Genotype With Pterygium
| العنوان: | The Association of MMP7 Genotype With Pterygium |
|---|---|
| المؤلفون: | HU, PEI-SHIN, WANG, YUN-CHI, LI, CHENG-HSI, LIAO, CHENG-HSI, HSIA, NING-YI, WU, MENG-FENG, YAN, JAI-SING, YANG, JAI-SING, CHIEN-CHIH, Y, YU, CHIEN-CHIH, CHA, WEN-SHIN, CHANG, WEN-SHIN, PEI-SHIN HU, YUN-CHI WANG, CHENG-HSI LI, CHENG-HSI LIAO, NING-YI HSIA, MENG-FENG WU, JAI-SING YAN, JAI-SING YANG, CHIEN-CHIH Y, CHIEN-CHIH YU, WEN-SHIN CHA, WEN-SHIN CHANG, 包大, Da-Tian Bau, CHIA-WEN TSA, CHIA-WEN TSAI, Bau, Da-Tian, TSA, CHIA-WEN, TSAI, CHIA-WEN |
| المساهمون: | 資訊電機學院生物資訊與醫學工程學系 |
| بيانات النشر: | 亞洲大學 |
| سنة النشر: | 2020 |
| المجموعة: | ASIA University, Taiwan: Instiutional Repository (ASIAIR) / 歡迎光臨亞洲大學全球資訊網 |
| مصطلحات موضوعية: | Age, gender, genotype, MMP7, polymorphism, pterygium Taiwan |
| الوصف: | Background/Aim: In literature, few studies have examined the diagnostic or prognostic potential of matrix metalloproteinases (MMP) in pterygium, whose formation and progression are closely related to imbalance in the extracellular microenvironment. In this study, we investigated the contribution of MMP7 promoter (A-181G and C-153T) polymorphic genotypes to pterygium risk. Materials and Methods: A total of 134 cases and 268 controls were collected and their MMP7 genotypes at A-181G and C-153T were examined by polymerase chain reaction-restriction fragment length polymorphism methodology. Results: The AA, AG and GG genotypes at MMP7 promoter A-181G were non-significantly differentially distributed between the two groups at 85.8, 11.2 and 3.0%, respectively, in pterygium cases and 88.4, 9.7 and 1.9% in controls, respectively (p for trend=0.6822). There was no polymorphic genotype for MMP7 C-153T among our Taiwanese cohort. Conclusion: A-181G and C-153T genotypes at MMP7 do not have a direct role in determining Taiwanese susceptibility to pterygium. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | Chinese |
| العلاقة: | IN VIVO; http://asiair.asia.edu.tw/ir/handle/310904400/113035Test; http://asiair.asia.edu.tw/ir/bitstream/310904400/113035/2/index.htmlTest |
| الإتاحة: | http://asiair.asia.edu.tw/ir/handle/310904400/113035Test http://asiair.asia.edu.tw/ir/bitstream/310904400/113035/2/index.htmlTest |
| رقم الانضمام: | edsbas.262E9B04 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |