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1رسالة جامعية
المؤلفون: Vila Currius, Mireia
المساهمون: University/Department: Universitat de Girona. Departament de Ciències Mèdiques
مرشدي الرسالة: Aldeguer i Manté, Xavier, Garcia-Gil, L. J.
المصدر: TDX (Tesis Doctorals en Xarxa)
مصطلحات موضوعية: Monitoratge de fàrmacs, Monitorización de fármacos, Drug monitoring, Farmacocinètica, Farmacocinética, Pharmacokinetics, Fàrmacs anti-TNF, Fármacos anti-TMF, Anti-TNF drugs, Malaltia inflamatòria intestinal, Enfermedad inflamatoria intestinal, Inflammatory bowel disease, Malaltia de Crohn, Enfermedad de Crohn, Crohn disease, Colitis ulcerosa, Ulcerative colitis, Factor de necrosi tumoral, Factor de necrosis tumoral, Tumor necrosis factor
الوقت: 616.3
وصف الملف: application/pdf
الوصول الحر: http://hdl.handle.net/10803/670009Test
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2رسالة جامعية
المؤلفون: Vidal Sancho, Laura
المساهمون: University/Department: Universitat de Girona. Departament de Ciències Mèdiques
مرشدي الرسالة: Xifró i Collsamata, Xavier, Verdú Navarro, Enrique
المصدر: TDX (Tesis Doctorals en Xarxa)
مصطلحات موضوعية: Malaltia de Huntington, Huntington disease, Enfermedad de Huntington, BDNF, Factor neurotròfic derivat del cervell, Brain derived neurotrophic factor, Factor neurotrófico derivado del cerebro, MEF2, Myocite enhancer factor 2, ERK5, Exracellular regulated kinase 5, EP2, Receptor 2 de la prostaglandina E2, Prostaglandin E2 receptor 2
الوقت: 616.8
وصف الملف: application/pdf
الوصول الحر: http://hdl.handle.net/10803/663460Test
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3رسالة جامعية
المؤلفون: Fenollosa Artés, Felip
المساهمون: University/Department: Universitat Politècnica de Catalunya. Departament d'Enginyeria Mecànica
مرشدي الرسالة: Buj Corral, Irene, Gomà Ayats, Joan Ramon
المصدر: TDX (Tesis Doctorals en Xarxa)
مصطلحات موضوعية: This doctoral thesis has been focused on the challenge to obtain, using Additive Manufacturing (AM), models for surgical planning, under the premise that the equipment to obtain them should be accessible to the hospital field. The objective is to spread the use of prototypes as a surgical training tool, upgrading medical practice in the same way that technologies which enhanced radiographs at the time. The reason for using AM, instead of more traditional technologies, is its capacity to materialise, in a straight way, the digital data of the patient anatomy coming from three-dimensional scanning systems, making it possible to achieve personalised models. The results are basically the generation of new knowledge in order to create accessible multi-material 3D printing machines that would allow to obtain models mimicking living tissues. Related to the will to spread this technology, research has focused on open source technologies, mainly Fused Filament Fabrication (FFF), and similar technologies based on catalitzable liquids. This research is aligned with the development work related to AM at CIM UPC, and in this special field there is a close cooperation with Hospital Sant Joan de Déu in Barcelona (HSJD). The first section of the thesis includes a description of the state of the art, including the existing technologies and their application within the medical field. For the first time, basis have been laid for the characterisation of living tissues – primarily soft tissues – to support the selection of materials mimicking them in an AM process, so as to improve the surgical planning experience. The stiffness linked to most of the materials commonly used in 3D printing, makes them unhelpful to simulate tumours and other anatomic references. Then, parameters like density, viscoelasticity, soft materials industry characterisation, soft tissues and vessels elastic modulus, its hardness, mimicking blood and sterilisation requirements, are successively treated. The second section starts exploring FFF 3D printing. Processes are classified from the point of view of multi-materiality, a key factor for surgical planning models, telling multi-nozzle solutions from mixing printheads solutions. A study about probable useful materials (both filaments and liquids) to mimic soft tissues is included. It is stated how liquids, compared to filaments, are more demanding related to additive manufacturing processes, and different ways to print very soft materials are detailed. Finally, six real cases – in which the doctorate has participated in these last years –, involving collaboration with HSJD, are reported. In the origin it can be found the difficulty to perform tumour resection surgeries to children, like neuroblastoma type, and the initiative of Dr. Lucas Krauel. Finally, Section 3 is devoted to the exploration of many concepts (up to 8), activity performed along the last five years thanks to the technical resources of CIM UPC and the academic activity of the UPC students, related to their final degree thesis, therefore reaching the construction of several machines and mechanisms to test them. The wide and systematic research about these concepts makes closer the day to reach a desktop 3D printing multimaterial solution. It is found that the best way to progress is having a plurality of independent printheads in order to enable a 3D printer to integrate some of the researched concepts, thus materialising a possible solution. To sum up, it is raised how a 3D printer for surgical training models should be like, for the purpose of serving as a basis for new developments., Àrees temàtiques de la UPC::Enginyeria mecànica
وصف الملف: application/pdf
الوصول الحر: http://hdl.handle.net/10803/667421Test
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4رسالة جامعية
المؤلفون: Badal Lafulla, Josep
المساهمون: University/Department: Universitat Autònoma de Barcelona. Departament de Cirurgia
مرشدي الرسالة: Zapata Victori, Miguel Ángel, García-Arumí, José
المصدر: TDX (Tesis Doctorals en Xarxa)
مصطلحات موضوعية: Degeneració maculada associada a l'edat, Degeneracón macular asociada a la edad, Age-related macular degeneration, PEDF (Pigment epithelium derived Factor), Neovascularitzxació coroidea, Neovascularización coroidea, Choroidal neovascularization, Ciències de la Salut
وصف الملف: application/pdf
الوصول الحر: http://hdl.handle.net/10803/370858Test
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5رسالة جامعية
المؤلفون: Estil·les Altimiras, Elisabet
المساهمون: University/Department: Universitat de Barcelona. Departament de Ciències Clíniques
مرشدي الرسالة: Montanya Mias, Eduard
المصدر: TDX (Tesis Doctorals en Xarxa)
مصطلحات موضوعية: Malalties del pàncrees, Enfermedades del páncreas, Pancréas diseases, Diabetis, Diabetes, Illots de Langerhans, Islotes de Langerhans, Islands of Langerhans, Insulin-like growth factor 2 (IGF2), Factor de crecimiento insulínico tipo 2, Factor de creixement insulínic tipus 2, Ciències de la Salut
الوقت: 616.4
وصف الملف: application/pdf
الوصول الحر: http://hdl.handle.net/10803/285812Test
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6رسالة جامعية
المؤلفون: Grande i Fullana, Iria
المساهمون: University/Department: Universitat de Barcelona. Facultat de Medicina
مرشدي الرسالة: Vieta i Pascual, Eduard, 1963-, Kapczinski, Flávio
المصدر: TDX (Tesis Doctorals en Xarxa)
مصطلحات موضوعية: Trastorn bipolar, Trastornos bipolares, Manic-depressive illness, Marcadors bioquímics, Marcadores bioquímicos, Biochemical markers, Estrès oxidatiu, Estrés oxidativo, Oxidative stress, Interleucina, Interleukin, Brain-derived neurotrophic factor (BDNF), Factor neurotrófico derivado del cerebro (BDNF), Factor neutròfic derivat del cervell (BDNF), Ciències de la Salut
الوقت: 616.89
وصف الملف: application/pdf
الوصول الحر: http://hdl.handle.net/10803/126065Test
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7رسالة جامعية
المؤلفون: Montané March, M. Amor
المساهمون: University/Department: Universitat Pompeu Fabra. Institut Universitari de Lingüística Aplicada
مرشدي الرسالة: Cabré, M. Teresa (Maria Teresa)
المصدر: TDX (Tesis Doctorals en Xarxa)
مصطلحات موضوعية: Terminologia, Ús, Normalització terminològica, Implantació terminològica, Cas normalitzat, Forma normalitzada, Forma no normalitzada, Grau d’implantació, Factor d’implantació, Terminology, Use, Terminology standardisation, Terminology implantation, Standardised case, Standardised form, Non standardised form, Implantation degree, Implantation factor
وصف الملف: application/pdf
الوصول الحر: http://hdl.handle.net/10803/97295Test
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8رسالة جامعية
المؤلفون: Sánchez Malagón, Josep
المساهمون: University/Department: Universitat Ramon Llull. FPCEEB - Ciències de l'Activitat Física i l'Esport
مرشدي الرسالة: Guerra Balic, Míriam, Brugada, Ramon
المصدر: TDX (Tesis Doctorals en Xarxa)
مصطلحات موضوعية: Factor neurotròfic derivat del cervell, BDNF, polimorfisme, val66met, recuperació cardíaca, tensió arterial, postesforç, exercici màxim, factor neurotrófico derivado del cerebro, polimorfismo, recuperación cardíaca, tensión arterial, postesfuerzo, ejercicio máximo, Brain Derived Neurotrophic Factor, polimorphism, heart rate recovery, blook pressure, post-effort, maximal exercise, Ciències de l'Activitat Física i de l'Esport
وصف الملف: application/pdf
الوصول الحر: http://hdl.handle.net/10803/66241Test
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9دورية أكاديمية
المؤلفون: Andrés Rodríguez, Nicanor Floro
المصدر: Farmacéuticos Comunitarios; Vol. 10, Núm. 3 (2018); p. 3-4
مصطلحات موضوعية: Investigación en farmacia, resultados en salud, indexación, factor de impacto, nueva etapa
وصف الملف: application/pdf
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10دورية أكاديمية
المؤلفون: Rodríguez, Nicanor Floro Andrés
المصدر: Farmacéuticos Comunitarios; Vol. 10, Núm. 2 (2018); p. 3-4
مصطلحات موضوعية: Investigación en farmacia, resultados en salud, indexación, factor de impacto, nueva etapa
وصف الملف: application/pdf