المؤلفون: Т. Т. Лахвіч, В. М. Рынейская, T. T. Lakhvich, V. M. Ryneiskaya

المصدر: Proceedings of the National Academy of Sciences of Belarus, Chemical Series; Том 59, № 1 (2023); 42-48 ; Известия Национальной академии наук Беларуси. Серия химических наук; Том 59, № 1 (2023); 42-48 ; 2524-2342 ; 1561-8331 ; 10.29235/1561-8331-2023-59-1

مصطلحات موضوعية: фармакафор, афіннасць, β-кетаацыл[АСР]сінтаза I, малекулярны докінг, рывараксабан, β-ketoacyl[ACP] synthase I, molecular docking, oxazolidinone, pharmacophore, Rivaroxaban

وصف الملف: application/pdf

العلاقة: https://vestichem.belnauka.by/jour/article/view/788/696Test; Treatment of Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis in Children: The Role of Bedaquiline and Delamanid / P. Francesco [et al.] // Microorganisms. – 2021. – Vol. 9, N 5. – Р. 10741091. https://doi.org/10.3390/microorganisms9051074Test; Marrakchi, H. Mycolic acids: Structures, biosynthesis, and beyond / H. Marrakchi, M. A. Laneelle, M. Daffe // Chem. Biol. – 2014. – Vol. 21. – P. 67–85. https://doi.org/10.1016/j.chembiol.2013.11.011Test; Dulberger, C. L. The mycobacterial cell envelope – a moving target / C. L. Dulberger, E. J. Rubin, C. Boutte // Nat. Rev. Microbiol. – 2020. – Vol. 18 – P. 47–59. https://doi.org/10.1038/s41579-019-0273-7Test; Abrahams, K. A. Mycobacterial drug discovery. / K. A. Abrahams, G. S. Besra // RSC Med. Chem. – 2020. – Vol. 11. – P. 1354–1365. https://doi.org/10.1039/D0MD00261ETest; Purification and biochemical characterization of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthases KasA and KasB / M. L. Schaeffer [et al.] // J. Biol. Chem. – 2001. – Vol. 276, N 50. – P. 47029–47037. https://doi.org/10.1074/jbc.m108903200Test; Platensimycin activity against mycobacterial beta-ketoacyl-ACP synthases / A. K. Brown [et al.] // PLoS One. – 2009. – Vol. 4. – P. e6306. https://doi.org/10.1371/journal.pone.0006306Test; Crystal structures of Mycobacterium tuberculosis KasA show mode of action within cell wall biosynthesis and its inhibition by thiolactomycin / S. R. Luckner [et al.] // Structure. – 2009. – Vol. 17, N 7. – P. 1004–1013. https://doi.org/10.1016/j.str.2009.04.012Test; Thiolactomycin-based inhibitors of bacterial beta-ketoacyl-ACP synthases with in vivo activity / G. R. Bommineni [et al.] // J. Med. Chem. – 2016. – Vol. 59. – P. 5377–5390. https://doi.org/10.1021/acs.jmedchem.6b00236Test; Synergistic lethality of a binary inhibitor of Mycobacterium tuberculosis KasA / P. Kumar [et al.] // mBio. – 2018. – Vol. 9. – P. e02101–e02117. https://doi.org/10.1128/mBio.02101-17Test; Inoyama, D. A preclinical candidate targeting Mycobacterium tuberculosis KasA / D. Inoyama, D. Awasthi, G. C. Capodagli // Cell Chem. Biol. – 2020. – Vol. 27. – P. 560–570. https://doi.org/10.1016/j.chembiol.2020.02.007Test; Лахвич, Ф. Ф. Рациональный дизайн модели ациклических аналогов гидроксиизонипекотиновых кислот / Ф. Ф. Лахвич, П. Ю. Зущик, Ф. А. Лахвич // БГМУ в авангарде медицинской науки и практики : сб. науч. тр. – Минск: БГМУ, 2019. – Вып. 9. – С. 389 – 399.; Лахвич, Ф. Ф. Исследование сродства альдонамидов к рецепторам KasA в контексте разработки противотуберкулезных препаратов / Ф. Ф. Лахвич, М. И. Борова // БГМУ в авангарде медицинской науки и практики: сб. науч. тр. – Минск: БГМУ, 2021. – Вып. 11. – C. 518–523.; Autodock4 and AutoDockTools4: automated docking with selective receptor flexibility / G. M. Morris [et al.] // Computational Chemistry. – 2009. – N 16. – P. 2785–2791. https://doi.org/10.1002/jcc.21256Test; Assessment report Xarelto Rivaroxaban [Electronic resource] / European Medicines Agency. – Режим доступа: https://www.ema.europa.eu/en/documents/variation-report/xarelto-h-c-944-x-0010-epar-assessment-report-extension_en.pdfTest. – Дата доступа: 01.06.2022.; https://vestichem.belnauka.by/jour/article/view/788Test

الإتاحة: https://doi.org/10.29235/1561-8331-2023-59-1-42-48Test
https://doi.org/10.29235/1561-8331-2023-59-1Test
https://doi.org/10.3390/microorganisms9051074Test
https://doi.org/10.1016/j.chembiol.2013.11.011Test
https://doi.org/10.1038/s41579-019-0273-7Test
https://doi.org/10.1039/D0MD00261ETest
https://doi.org/10.1074/jbc.m108903200Test
https://doi.org/10.1371/journal.pone.0006306Test
https://doi.org/10.1016/j.str.2009.04.012Test
https://doi.org/10.1021/acs.jmedchem.6b00236Test

المؤلفون: Yaroslav V. Faletrov, Veronika S. Karpushenkova, Viktoryia A. Zavalinich, Polina S. Yakovets, Anastasia D. Shkredava, Vladimir M. Shkumatov

المصدر: Журнал Белорусского государственного университета: Химия, Iss 2, Pp 25-35 (2021)

مصطلحات موضوعية: bovine serum albumin, fluorescence, nitrobenzoxadiazoles, docking, Chemistry, QD1-999

وصف الملف: electronic resource

العلاقة: https://journals.bsu.by/index.php/chemistry/article/view/4099Test; https://doaj.org/toc/2520-257XTest; https://doaj.org/toc/2617-3980Test

الوصول الحر: https://doaj.org/article/daf6af8ca8e147dcb1086e2a69ae2728Test

المؤلفون: Yaroslav V. Faletrov, Liliya I. Glinskaya, Matvey S. Horetski, Jan V. Panada, Nina S. Frolova, Vladimir M. Shkumatov

المصدر: Журнал Белорусского государственного университета: Химия, Iss 1, Pp 21-27 (2021)

مصطلحات موضوعية: p450, fluorescence, azoles, inhibitors, docking, ciprofioxacin, Chemistry, QD1-999

وصف الملف: electronic resource

العلاقة: https://journals.bsu.by/index.php/chemistry/article/view/3582Test; https://doaj.org/toc/2520-257XTest; https://doaj.org/toc/2617-3980Test

الوصول الحر: https://doaj.org/article/aabce7a169f94000b8e64dbb869bd8b8Test

المؤلفون: Cyril M. Verbilo, Alexander V. Zuraev, Yuri V. Grigoriev, Vladislav A. Budevich, Oleg A. Ivashkevich

المصدر: Журнал Белорусского государственного университета: Химия, Iss 1, Pp 48-63 (2020)

مصطلحات موضوعية: molecular modeling, docking, antibacterial activity, e. coli, s. aureus, 1н-1,2,3-triazoles, Chemistry, QD1-999

وصف الملف: electronic resource

العلاقة: https://journals.bsu.by/index.php/chemistry/article/view/1278Test; https://doaj.org/toc/2520-257XTest; https://doaj.org/toc/2617-3980Test

الوصول الحر: https://doaj.org/article/502ba7fb953941ccaf6bf1db912bb88aTest

المؤلفون: Ян U. Panada, Yaroslav V. Faletrov, Nina S. Frolova, Vladimir M. Shkumatov

المصدر: Журнал Белорусского государственного университета: Химия, Iss 1, Pp 28-34 (2018)

مصطلحات موضوعية: indole steroids, cytochrome p450, molecular docking, Chemistry, QD1-999

وصف الملف: electronic resource

العلاقة: https://journals.bsu.by/index.php/chemistry/article/view/1218Test; https://doaj.org/toc/2520-257XTest; https://doaj.org/toc/2617-3980Test

الوصول الحر: https://doaj.org/article/d5de38aef5894a538596a5ab52ea390dTest

المؤلفون: Matvey S. Horetski, Yaroslav V. Faletrov, Elena V. Rudaya, Vladimir M. Shkumatov

المصدر: Журнал Белорусского государственного университета: Химия, Iss 1, Pp 22-27 (2018)

مصطلحات موضوعية: bodipy, fluorescence, cytochrome p450, stard1, docking, quantum chemical calculations, Chemistry, QD1-999

وصف الملف: electronic resource

العلاقة: https://journals.bsu.by/index.php/chemistry/article/view/1217Test; https://doaj.org/toc/2520-257XTest; https://doaj.org/toc/2617-3980Test

الوصول الحر: https://doaj.org/article/f1e4aa4543004fa69b9342a5987e95a2Test

المؤلفون: Veronika S. Karpushenkova, Viktoryia A. Zavalinich, Vladimir M. Shkumatov, Y. V. Faletrov, Anastasia D. Shkredava, Polina S. Yakovets

المصدر: Журнал Белорусского государственного университета: Химия, Iss 2, Pp 25-35 (2021)

مصطلحات موضوعية: biology, Chemistry, In silico, Combinatorial chemistry, In vitro, nitrobenzoxadiazoles, Piperazine, chemistry.chemical_compound, Aniline, bovine serum albumin, docking, biology.protein, fluorescence, Bovine serum albumin, QD1-999

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71d462559b94af4321965496667a6c6Test
https://journals.bsu.by/index.php/chemistry/article/view/4099Test