دورية أكاديمية
Degree of cognitive impairment in patients with carotid stenosis in relation to cerebral ischemic lesions
| العنوان: | Degree of cognitive impairment in patients with carotid stenosis in relation to cerebral ischemic lesions |
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| المؤلفون: | Joveva Elena, Ðorđević Gordana, Milošević Vuk, Arsovska Anita, Živković Miroslava |
| المصدر: | Vojnosanitetski Pregled, Vol 79, Iss 2, Pp 150-154 (2022) |
| بيانات النشر: | Military Health Department, Ministry of Defance, Serbia, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Medicine (General) |
| مصطلحات موضوعية: | cognition disorders, carotid stenosis, diagnosis, magnetic resonance imaging, severity of illness index, risk factors, x-ray computed tomography, Medicine (General), R5-920 |
| الوصف: | Background/Aim. Carotid stenosis is a risk factor for cognitive impairment. The aim of the study was to evaluate the degree of cognitive impairment in patients with asymp-tomatic and symptomatic carotid stenosis and correlate it with the presence, location, and extent of cerebral ischemic lesions. Methods. A prospective analysis of 180 patients aged 50–70 years, divided into three groups (asymptomatic carotid stenosis, symptomatic carotid stenosis, and controls) was made. We assessed demographic characteristics, vascu-lar risk factors, ultrasound examination of the carotid arter-ies, computerized tomography (CT), magnetic resonance imaging (MRI) of the brain, and neuropsychological testing. Results. The brain CT findings on admission showed is-chemic lesions in the left hemisphere in 13.3% of patients in the asymptomatic group and in 41% of those in the symp-tomatic group. In the right hemisphere, lesions were regis-tered in 10% of the asymptomatic patients and in 46.7% of the symptomatic patients. The difference between groups was statistically significant. The lesion volumes measured on CT and MRI scans were significantly different (p < 0.001) between groups with asymptomatic and symptomatic carot-id stenosis. The degree of cognitive impairment, measured by the Addenbrooke's Cognitive Examination Revised (ACE-R), was significantly different between the groups (p < 0.05), with the most severe deficit in the symptomatic group. Conclusion. Our study has shown that cognitive impairment was more severe in patients with symptomatic carotid stenosis, compared to the patients with asymptomat-ic carotid stenosis. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Serbian |
| تدمد: | 0042-8450 2406-0720 20050208 |
| العلاقة: | https://doaj.org/toc/0042-8450Test; https://doaj.org/toc/2406-0720Test |
| DOI: | 10.2298/VSP200502082J |
| الوصول الحر: | https://doaj.org/article/d21a77d7f0eb4d10a0d3bf62690d0c71Test |
| رقم الانضمام: | edsdoj.21a77d7f0eb4d10a0d3bf62690d0c71 |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 00428450 24060720 20050208 |
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| DOI: | 10.2298/VSP200502082J |