التفاصيل البيبلوغرافية
| العنوان: |
Case Report: Meningioma with Granulofilamentous Inclusions. |
| المؤلفون: |
Horiguchi, Hidehisa, Hirose, Takanori, Sano, Toshiaki, Nagahiro, Shinji, Seki, Kunihiko, Fujimoto, Naomi, Kaneko, Fumihito, Kusaka, Kazumasa |
| المصدر: |
Ultrastructural Pathology; Jul2000, Vol. 24 Issue 4, p267-271, 5p |
| مصطلحات موضوعية: |
MENINGIOMA, TRIGEMINAL neuralgia |
| مستخلص: |
The authors report a case of intracranial meningioma with granulofilamentous inclusions. A 50-year-old man had right trigeminal neuralgia due to trigeminal nerve compression by a petroclival tumor and received tumor resection. Microscopically, tumor cells containing eccentric nuclei and intracytoplasmic hyaline inclusions were arranged in sheets and whorls. The inclusions were negative for periodic acid-Schiff reaction. No histological anaplasia was seen. Immunohistochemistry showed epithelial membrane antigen reactivity on the cytoplasmic membrane. Immunoreactivity for vimentin was recognized in cytoplasm adjacent to inclusions. However, confocal laser microscopic study revealed immunoreactivity for vimentin even inside some inclusions. Ultrastructurally, interdigitation of cytoplasmic processes and desmosomes connecting adjacent cells were noted. Inclusions were composed of numerous fine osmiophilic granules attached by intermediates filaments. These findings were consistent with a meningioma with the granulofilamentous inclusions described earlier. The findings demonstrated by confocal laser microscopy and electron microscopy suggest that these granular materials may be the metabolic products of vimentin filaments. [ABSTRACT FROM AUTHOR] |
|
Copyright of Ultrastructural Pathology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
