دورية أكاديمية
Current Diagnosis and Management of Hypersensitivity Pneumonitis
| العنوان: | Current Diagnosis and Management of Hypersensitivity Pneumonitis |
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| المؤلفون: | Paolo Maria Leone, M.D., Luca Richeldi, M.D., Ph.D. |
| المصدر: | Tuberculosis and Respiratory Diseases, Vol 83, Iss 1, Pp 122-131 (2020) |
| بيانات النشر: | The Korean Academy of Tuberculosis and Respiratory Diseases, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Diseases of the respiratory system |
| مصطلحات موضوعية: | hypersensitivity pneumonitis, lung diseases, interstitial, fibrosis, diagnosis, management, high resolution computed tomography, therapy, steroids, antigens, nintedanib, pirfenidone, Diseases of the respiratory system, RC705-779 |
| الوصف: | Hypersensitivity Pneumonitis (HP) one of the most common interstitial lung diseases (ILDs) is characterized by exposure to an inhaled inciting antigen that leads to a host immunologic reaction determining interstitial inflammation and architectural distortion. The underlying pathogenetic mechanisms are unclear. The absence of international shared diagnostic guidelines and the lack of a “gold-standard” test for HP combined with the presence of several clinical and radiologic overlapping features makes it particularly challenging to differentiate HP from other ILDs, also in expert contests. Radiology is playing a more crucial role in this process; recently the headcheese sign was recognized as a more specific for chronic-HP than the extensive mosaic attenuation. Several classification proposals and diagnostic models have been advanced by different groups, with no prospective validation. Therapeutic options for HP have been limited to antigen avoidance and immunosuppressant drugs over the last decades. Several questions about this condition remain unanswered and there is a need for more studies. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1738-3536 2005-6184 |
| العلاقة: | https://e-trd.org/search.php?where=aview&id=10.4046/trd.2020.0012&code=0003TRD&vmode=FULLTest; https://doaj.org/toc/1738-3536Test; https://doaj.org/toc/2005-6184Test |
| DOI: | 10.4046/trd.2020.0012&code=0003TRD&vmode=FULL |
| الوصول الحر: | https://doaj.org/article/3c5a6ba529fb4ea6bb90420784f45d3bTest |
| رقم الانضمام: | edsdoj.3c5a6ba529fb4ea6bb90420784f45d3b |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 17383536 20056184 |
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| DOI: | 10.4046/trd.2020.0012&code=0003TRD&vmode=FULL |