Chemotherapy in conjunction with traditional Chinese medicine for survival of patients with early female breast cancer: protocol for a non-randomized, single center prospective cohort study
| العنوان: | Chemotherapy in conjunction with traditional Chinese medicine for survival of patients with early female breast cancer: protocol for a non-randomized, single center prospective cohort study |
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| المؤلفون: | Ming-Yen Tsai, Chien-Ting Liu, Yu-Chuen Huang, Shih-Yu Chen, Yen-Hao Chen |
| المصدر: | Trials Trials, Vol 20, Iss 1, Pp 1-8 (2019) |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Adult, Quality of life, medicine.medical_specialty, Disease-free survival, Taiwan, Medicine (miscellaneous), Antineoplastic Agents, Breast Neoplasms, Traditional Chinese medicine, Single Center, Meridians, Cohort Studies, 03 medical and health sciences, Study Protocol, 0302 clinical medicine, Breast cancer, Internal medicine, medicine, Humans, Pharmacology (medical), 030212 general & internal medicine, Prospective Studies, Medicine, Chinese Traditional, Prospective cohort study, lcsh:R5-920, business.industry, Cancer, Study design, medicine.disease, Prognosis, Combined Modality Therapy, Clinical trial, Treatment Outcome, Chemotherapy, Adjuvant, 030220 oncology & carcinogenesis, Female, Neoplasm Recurrence, Local, business, lcsh:Medicine (General), Cohort study |
| الوصف: | Background Chemotherapy after surgery for breast cancer plays a fundamental role in reducing the risk of distant and local recurrence. An increasing number of patients seek traditional Chinese medicine (TCM) during adjuvant chemotherapy to relieve symptom discomfort and side effects as well as to strengthen the body’s defenses. However, evidence on how concurrent TCM treatment affects prognosis is scarce. This trial aims to evaluate the association between TCM treatment and disease-free survival outcomes for patients with early breast cancer who are undergoing adjuvant chemotherapy. Methods/design This is a non-randomized, single center, prospective cohort study begun in November 2018 in Kaohsiung, Taiwan. A sample of 310 participants diagnosed with early breast cancer was recruited from the Breast Cancer Research Team and will be followed up every 3 to 6 months until October 2023. Detailed information of the participants, including general information, history of cancer, quality of life, side effects and safety of treatment, TCM body constitution, and meridian energy analysis, was collected face to face at baseline. Discussion This is the first prospective observational cohort study on TCM in patients with early breast cancer who are receiving adjuvant chemotherapy to evaluate the prognosis. Through this trial, we hope to assess the feasibility of a larger-scale clinical trial in the future and formulate an integrated TCM care program. Trial registration ClinicalTrials.gov, NCT03797248. Registered on 5 January 2019. |
| تدمد: | 1745-6215 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7760867a7d8b6b6254b9ceb79d07e5bTest https://pubmed.ncbi.nlm.nih.gov/31847861Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....a7760867a7d8b6b6254b9ceb79d07e5b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17456215 |
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