التفاصيل البيبلوغرافية
| العنوان: |
Dissecting Glioma Invasiveness in a 3D-Organotypic Model. |
| المؤلفون: |
Codega, Paolo1, Mellinghoff, Ingo K.1,2,3 mellingi@mskcc.org |
| المصدر: |
Trends in Molecular Medicine. Sep2017, Vol. 23 Issue 9, p776-777. 2p. |
| مصطلحات موضوعية: |
*INTERFERONS, *BRAIN diseases, *GLIOMAS, *GENETIC repressors, *ANEURYSMS |
| مستخلص: |
Diffuse brain infiltration by tumor cells is a hallmark of glioma. Molecular mechanisms of brain invasion are poorly understood due to the difficulty to model this process in culture. A new study published in Cell Reports developed a three-dimensional organotypic model and identified interferon regulatory factor 3 (IRF3) as repressor of glioma invasion. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |
