دورية أكاديمية

Intrinsically Disordered Proteins Adaptively Reorganize Cellular Matter During Stress.

التفاصيل البيبلوغرافية
العنوان: Intrinsically Disordered Proteins Adaptively Reorganize Cellular Matter During Stress.
المؤلفون: Chavali, Sreenivas1 schavali@mrc-lmb.cam.ac.uk, Gunnarsson, Alexander1, Babu, M. Madan1 madanm@mrc-lmb.cam.ac.uk
المصدر: Trends in Biochemical Sciences. Jun2017, Vol. 42 Issue 6, p410-412. 3p.
مصطلحات موضوعية: *CELL death, *PHYSIOLOGICAL adaptation, *PHYSIOLOGICAL stress, *DEHYDRATION, *AMORPHOUS substances
مستخلص: Intrinsically disordered proteins (IDPs) can protect cells from diverse stresses by forming higher order assemblies such as reversible aggregates or granules. Recently, Boothby et al. show that IDPs protect tardigrades against desiccation by forming a glass-like amorphous matrix, highlighting that material properties of disordered proteins can confer adaptation during stress. [ABSTRACT FROM AUTHOR]
قاعدة البيانات: Academic Search Index
الوصف
تدمد:09680004
DOI:10.1016/j.tibs.2017.04.007