Thrombotic Thrombocytopenic Purpura: A Multimodality Model of Treatment Including Plasma Exchange, i.v. Immunoglobulin, Prednisone, Antiplatelet Agents, Vincristine and Splenectomy
| العنوان: | Thrombotic Thrombocytopenic Purpura: A Multimodality Model of Treatment Including Plasma Exchange, i.v. Immunoglobulin, Prednisone, Antiplatelet Agents, Vincristine and Splenectomy |
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| المؤلفون: | H. Bouronikou, John Dervenoulas, Sotos Raptis, Vassiliki Pappa, T. Economopoulos, Efstathios Papageorgiou, A. Stavrou, M Belia, D. Karakassis, S. Stylogiannis |
| المصدر: | Transfusion Medicine and Hemotherapy. 19:294-296 |
| بيانات النشر: | S. Karger AG, 1992. |
| سنة النشر: | 1992 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Vincristine, Resuscitation, medicine.medical_treatment, Splenectomy, Thrombotic thrombocytopenic purpura, Hematocrit, Plasma, Prednisone, Immunopathology, medicine, Humans, Immunology and Allergy, Aged, Aged, 80 and over, Aspirin, L-Lactate Dehydrogenase, Plasma Exchange, Purpura, Thrombotic Thrombocytopenic, medicine.diagnostic_test, Platelet Count, business.industry, Immunization, Passive, Dipyridamole, Hematology, Middle Aged, medicine.disease, Combined Modality Therapy, Surgery, Purpura, Female, medicine.symptom, business, Platelet Aggregation Inhibitors, medicine.drug |
| الوصف: | Thirteen patients with thrombotic thrombocytopenic purpura were treated at our facility between 1985 and 1991. All patients were treated with plasma therapy (both plasma exchange and plasma infusions), prednisone, intravenous immunoglobulin, and antiplatelet agents. Twelve patients achieved remission (92.3%). One patient died from cerebral hemorrhage. Vincristine was administered to 5 patients who did not respond after the first two plasmaphereses. Splenectomy was performed in a patient who relapsed four times within a 2-year period. From the 12 patients achieving remission, 11 have been still in remission for a period of 3 to 69 months. |
| تدمد: | 1660-3818 1660-3796 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7200bcd5d5e0e1baa7918bcd60c7beeTest https://doi.org/10.1159/000222651Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....a7200bcd5d5e0e1baa7918bcd60c7bee |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16603818 16603796 |
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