دورية أكاديمية
Combined impact of healthy lifestyle factors on risk of asthma, rhinoconjunctivitis and eczema in school children: ISAAC phase III
| العنوان: | Combined impact of healthy lifestyle factors on risk of asthma, rhinoconjunctivitis and eczema in school children: ISAAC phase III |
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| المؤلفون: | Morales, Eva, Strachan, David, Asher, Innes, Ellwood, Philippa, Pearce, Neil, Garcia-Marcos, Luis, Ait-Khaled, N., Anderson, H. R., Asher, M. I., Beasley, R., Bjorksten, B., Brunekreef, B., Crane, J., Ellwood, P., Garcia-Marcos, L., Foliaki, S., Keil, U., Lai, C. K. W., Mallol, J., Robertson, C. F., Mitchell, E. A., Montefort, S., Odhiambo, J., Pearce, N., Shah, J., Stewart, A. W., Strachan, D., von Mutius, E., Weiland, S. K., Weinmayr, G., Williams, H., Wong, G., Clayton, T. O., Amarales, L., Aguilar, P., Cepeda, A. M., Aristizabal, G., Riikjarv, M-A, Zsigmond, G., Kartasasmita, C. B., Masjedi, M-R, Odajima, H., Kudzyte, J., Del-Rio-Navarro, B. E., Barragan-Meijueiro, M., Garcia-Almaraz, R., Baeza-Bacab, M., Gonzalez-Diaz, S. N., Linares-Zapien, F. J., Pattemore, P. |
| المصدر: | Thorax |
| بيانات النشر: | Ludwig-Maximilians-Universität München |
| سنة النشر: | 2019 |
| المجموعة: | Open Access LMU (Ludwig-Maximilians-University Munich) |
| مصطلحات موضوعية: | Medizin, ddc:610 |
| الوصف: | Background Asthma is not the key focus of prevention strategies. A Healthy Lifestyle Index (HLI) was developed to examine the combined effect of modifiable lifestyle factors on asthma, rhinoconjunctivitis and eczema using data from the International Study of Asthma and Allergies in Childhood (ISAAC) phase III. Methods Information on symptoms of asthma, rhinoconjunctivitis, eczema and several lifestyle factors was obtained from children aged 6-7 years through written questionnaires. The HLI combined five lifestyle factors: no parental smoking, child's adherence to Mediterranean diet, child's healthy body mass index, high physical activity and non-sedentary behaviour. The association between the HLI and risk of asthma, rhinoconjunctivitis and eczema was evaluated using multilevel mixed-effects logistic regression models. Findings Data of 70 795 children from 37 centres in 19 countries were analysed. Each additional healthy lifestyle factor was associated with a reduced risk of current wheeze (OR 0.87, 95% CI 0.84 to 0.89), asthma ever (OR 0.89, 95% CI 0.87 to 0.92), current symptoms of rhinoconjunctivitis (OR 0.95, 95% CI 0.92 to 0.97) and current symptoms of eczema (OR 0.92, 95% CI 0.92 to 0.98). Theoretically, if associations were causal, a combination of four or five healthy lifestyle factors would result into a reduction up to 16% of asthma cases (ranging from 2.7% to 26.3 % according to region of the world). Conclusions These findings should be interpreted with caution given the limitations to infer causality from cross-sectional observational data. Efficacy of interventions to improve multiple modifiable lifestyle factors to reduce the burden asthma and allergy in childhood should be assessed. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | Morales, Eva; Strachan, David; Asher, Innes; Ellwood, Philippa; Pearce, Neil; Garcia-Marcos, Luis; Ait-Khaled, N.; Anderson, H. R.; Asher, M. I.; Beasley, R.; Bjorksten, B.; Brunekreef, B.; Crane, J.; Ellwood, P.; Garcia-Marcos, L.; Foliaki, S.; Keil, U.; Lai, C. K. W.; Mallol, J.; Robertson, C. F.; Mitchell, E. A.; Montefort, S.; Odhiambo, J.; Pearce, N.; Shah, J.; Stewart, A. W.; Strachan, D.; von Mutius, E.; Weiland, S. K.; Weinmayr, G.; Williams, H.; Wong, G.; Asher, M. I.; Clayton, T. O.; Ellwood, P.; Mitchell, E. A.; Stewart, A. W.; Amarales, L.; Aguilar, P.; Cepeda, A. M.; Aristizabal, G.; Riikjarv, M-A; Zsigmond, G.; Kartasasmita, C. B.; Masjedi, M-R; Odajima, H.; Kudzyte, J.; Del-Rio-Navarro, B. E.; Barragan-Meijueiro, M.; Garcia-Almaraz, R.; Baeza-Bacab, M.; Gonzalez-Diaz, S. N.; Linares-Zapien, F. J.; Asher, M. I.; Pattemore, P. (2019): Combined impact of healthy lifestyle factors on risk of asthma, rhinoconjunctivitis and eczema in school children: ISAAC phase III. In: Thorax, Vol. 74, Nr. 6: S. 531-538 [PDF, 1MB]; https://epub.ub.uni-muenchen.de/81184/1/531.full.pdfTest; http://nbn-resolving.de/urn:nbn:de:bvb:19-epub-81184-6Test; https://epub.ub.uni-muenchen.de/81184Test/ |
| DOI: | 10.1136/thoraxjnl-2018-212668 |
| الإتاحة: | https://doi.org/10.1136/thoraxjnl-2018-212668Test https://epub.ub.uni-muenchen.de/81184/1/531.full.pdfTest https://epub.ub.uni-muenchen.de/81184Test/ http://nbn-resolving.de/urn:nbn:de:bvb:19-epub-81184-6Test |
| حقوق: | This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively |
| رقم الانضمام: | edsbas.6C227392 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1136/thoraxjnl-2018-212668 |
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