دورية أكاديمية
Tumor vessel normalization and immunotherapy in gastric cancer
العنوان: | Tumor vessel normalization and immunotherapy in gastric cancer |
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المؤلفون: | Xianzhe Yu, Shan He, Jian Shen, Qiushi Huang, Peng Yang, Lin Huang, Dan Pu, Li Wang, Lu Li, Jinghua Liu, Zelong Liu, Lingling Zhu |
المصدر: | Therapeutic Advances in Medical Oncology, Vol 14 (2022) |
بيانات النشر: | SAGE Publishing, 2022. |
سنة النشر: | 2022 |
المجموعة: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
مصطلحات موضوعية: | Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
الوصف: | Gastric cancer (GC) is a common malignant tumor, and patients with GC have a low survival rate due to limited effective treatment methods. Angiogenesis and immune evasion are two key processes in GC progression, and they act synergistically to promote tumor progression. Tumor vascular normalization has been shown to improve the efficacy of cancer immunotherapy, which in turn may be improved through enhanced immune stimulation. Therefore, it may be interesting to identify synergies between immunomodulatory agents and anti-angiogenic therapies in GC. This strategy aims to normalize the tumor microenvironment through the action of the anti-vascular endothelial growth factor while stimulating the immune response through immunotherapy and prolonging the survival of GC patients. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1758-8359 17588359 |
العلاقة: | https://doaj.org/toc/1758-8359Test |
DOI: | 10.1177/17588359221110176 |
الوصول الحر: | https://doaj.org/article/54bf0bc47c54406f97b1fe3709b3158eTest |
رقم الانضمام: | edsdoj.54bf0bc47c54406f97b1fe3709b3158e |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 17588359 |
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DOI: | 10.1177/17588359221110176 |