المؤلفون: Hamid, Omid, Robert, Caroline, Daud, Adil, Hodi, F Stephen, Hwu, Wen-Jen, Kefford, Richard, Wolchok, Jedd D, Hersey, Peter, Joseph, Richard W, Weber, Jeffrey S, Dronca, Roxana, Gangadhar, Tara C, Patnaik, Amita, Zarour, Hassane, Joshua, Anthony M, Gergich, Kevin, Elassaiss-Schaap, Jeroen, Algazi, Alain, Mateus, Christine, Boasberg, Peter, Tumeh, Paul C, Chmielowski, Bartosz, Ebbinghaus, Scot W, Li, Xiaoyun Nicole, Kang, S Peter, Ribas, Antoni

المصدر: The New England journal of medicine. 369(2)

مصطلحات موضوعية: Humans, Melanoma, Brain Neoplasms, Skin Neoplasms, Antineoplastic Agents, Antibodies, Monoclonal, Drug Administration Schedule, Dose-Response Relationship, Drug, Adult, Aged, Aged, 80 and over, Middle Aged, Female, Male, Antibodies, Monoclonal, Humanized, Programmed Cell Death 1 Receptor, Human Genome, Genetics, Clinical Research, Patient Safety, Clinical Trials and Supportive Activities, Cancer, Medical and Health Sciences, General & Internal Medicine

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3bc5s56xTest

المؤلفون: Steven Lemery, Patricia Keegan, Richard Pazdur

المصدر: The New England journal of medicine. 377(15)

مصطلحات موضوعية: 0301 basic medicine, Oncology, Adult, Male, medicine.medical_specialty, Programmed Cell Death 1 Receptor, Antineoplastic Agents, Breast Neoplasms, Pembrolizumab, Antibodies, Monoclonal, Humanized, Digestive System Neoplasms, B7-H1 Antigen, 03 medical and health sciences, 0302 clinical medicine, Neoplastic Syndromes, Hereditary, Internal medicine, medicine, Drug approval, Biomarkers, Tumor, Humans, Neoplasm Metastasis, Child, Drug Approval, business.industry, Brain Neoplasms, United States Food and Drug Administration, Fda approval, Cancer, General Medicine, medicine.disease, Tumor site, United States, Surgery, 030104 developmental biology, 030220 oncology & carcinogenesis, Monoclonal, Biomarker (medicine), Female, Microsatellite Instability, Programmed death 1, business, Colorectal Neoplasms, Urogenital Neoplasms

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68427c62967763e5fc6960ce76a05dbcTest
https://pubmed.ncbi.nlm.nih.gov/29020592Test

المؤلفون: Matthew T. Campbell, Christian Kollmannsberger, Bo Huang, Mariangela Mariani, Jae L. Lee, Balaji Venugopal, John B. A. G. Haanen, Paul B. Robbins, Camilla Fowst, Boris Alekseev, Motohide Uemura, Jing Wang, Alessandra di Pietro, Konstantin Penkov, Robert J. Motzer, Toni K. Choueiri, Michael B. Atkins, Brian I. Rini, Howard Gurney, Aleksander Chudnovsky, James Larkin, Subramanian Hariharan, Wilson H. Miller, Manuela Schmidinger, Aleksandr Vasiliev, Sylvie Negrier, Jens Bedke, Laurence Albiges

المصدر: Translational Cancer Research

مصطلحات موضوعية: Oncology, Adult, Male, medicine.medical_specialty, Axitinib, Programmed Cell Death 1 Receptor, Antineoplastic Agents, 030204 cardiovascular system & hematology, Antibodies, Monoclonal, Humanized, law.invention, Avelumab, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, Renal cell carcinoma, law, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Carcinoma, Sunitinib, Humans, Single-Blind Method, 030212 general & internal medicine, Progression-free survival, Carcinoma, Renal Cell, Aged, Aged, 80 and over, business.industry, Antibodies, Monoclonal, General Medicine, Middle Aged, medicine.disease, Kidney Neoplasms, Progression-Free Survival, Clinical trial, Survival Rate, Editorial Commentary, Administration, Intravenous, Female, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17373ecbc5219968a1002917c8de7e81Test
https://pubmed.ncbi.nlm.nih.gov/35117136Test

المؤلفون: Matthew G. Fury, Kosalai Kal Mohan, Jade Homsi, Irene Brana, Anne Lynn S. Chang, Dirk Schadendorf, Jiaxin Niu, Leonel Hernandez-Aya, Jingjin Li, Alexander Guminski, Badri Modi, Israel Lowy, Jocelyn Booth, Victor Moreno, Melissa Lynne Johnson, Elizabeth Stankevich, Christine H. Chung, Kyriakos P. Papadopoulos, Hani M. Babiker, Michael R. Migden, Brett G.M. Hughes, Lara Dunn, Danny Rischin, Taofeek K. Owonikoko, Alesha A. Thai, Melissa Mathias, George D. Yancopoulos, Frank Seebach, Karl D. Lewis, Annette M. Lim, Guilherme Rabinowits, Marta Gil-Martin, Nikhil I. Khushalani, Axel Hauschild, Bo Gao, Chrysalyne D. Schmults, Siyu Li

المصدر: The New England journal of medicine. 379(4)

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Skin Neoplasms, Nausea, medicine.medical_treatment, Programmed Cell Death 1 Receptor, Medizin, Phases of clinical research, Antineoplastic Agents, Antibodies, Monoclonal, Humanized, Gastroenterology, Disease-Free Survival, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Carcinoma, Humans, Adverse effect, Aged, Neoplasm Staging, Aged, 80 and over, Dose-Response Relationship, Drug, business.industry, Antibodies, Monoclonal, Immunosuppression, General Medicine, Middle Aged, medicine.disease, Rash, Clinical trial, 030104 developmental biology, 030220 oncology & carcinogenesis, Cohort, Carcinoma, Squamous Cell, Female, Immunotherapy, medicine.symptom, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1761b684cca8899712eec3d870da07b1Test
https://pubmed.ncbi.nlm.nih.gov/29921845Test

المؤلفون: Ariella Coler-Reilly, Yasuhiro Hasegawa, Yoshihisa Yamano, Rie Furuta, Masao Matsuoka, Toshiki Watanabe, Eisuke Inoue, Kaoru Uchimaru, Natsumi Araya, Naoki Matsumoto, Tomoo Sato, Naoko Yagishita

المصدر: The New England journal of medicine. 378(6)

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Receptors, CCR4, medicine.drug_class, T-Lymphocytes, Inflammation, Antineoplastic Agents, Monoclonal antibody, Antibodies, Monoclonal, Humanized, Gastroenterology, Drug Administration Schedule, 03 medical and health sciences, Pharmacokinetics, immune system diseases, hemic and lymphatic diseases, Internal medicine, Mogamulizumab, Medicine, Humans, Aged, Human T-lymphotropic virus 1, biology, Dose-Response Relationship, Drug, business.industry, food and beverages, virus diseases, General Medicine, Exanthema, Middle Aged, Viral Load, Paraparesis, Tropical Spastic, Dose–response relationship, 030104 developmental biology, Area Under Curve, Monoclonal, biology.protein, Female, Antibody, medicine.symptom, business, Viral load, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9c37b43fb505ee2d5bb829b0cf8cb9Test
https://pubmed.ncbi.nlm.nih.gov/29414279Test

المؤلفون: Robert, Caroline, Schachter, Jacob, Long, Georgina V, Arance, Ana, Grob, Jean Jacques, Mortier, Laurent, Daud, Adil, Carlino, Matteo S, McNeil, Catriona, Lotem, Michal, Larkin, James, Lorigan, Paul, Neyns, Bart, Blank, Christian U, Hamid, Omid, Mateus, Christine, Shapira-Frommer, Ronnie, Kosh, Michele, Zhou, Honghong, Ibrahim, Nageatte, Ebbinghaus, Scot, Ribas, Antoni, Cebon, Jonathan, Hersey, Peter, Long, Georgina, Millward, Michael, Walpole, Euan, Höller, Christoph, Kehrer, Helmut, Richtig, Erika, Schmuth, Matthias, Baurain, Jean-François, Wolter, Pascal, Butler, Marcus, McWhirter, Elaine, Miller, Wilson, Petrella, Teresa, Acevedo, Alejandro, Caglevic, Christian, Morales, Luisa, Sanchez, Jesús, Yepes, Andres, Zambrano, Angela Regina, Avril, Marie-Francoise, Dutriaux, Caroline, Guilot, Bernard, Lacour, Jean-Phillippe, Leccia, Marie-Therese, Legoupil, Delphine, Lebbe, Celeste, Machet, Laurent, Berking, Carola, Loquai, Carmen, Mohr, Peter, Schadendorf, Dirk, Utikal, Jochen, Bar-Sela, Gil, Blank, Christian, Barrow, Catherine, Fitzharris, Bernie, Kersten, Christian, Nyakas, Marta, Straume, Oddbjørn, Berrocal, Alfonso, Cortes, Javier, Espinosa, Enrique, Lopez-Martin, Jose, Martin-Algarra, Salvador, Masucci, Giuseppe, Papworth, Karin, Ullenhag, Gustav, Brown, Ewan, Chao, David, Evans, Thomas, Middleton, Mark, Skaria, Sunil, Steven, Neil, Agarwala, Sanjiv, Bhatia, Shailender, Gangadhar, Tara, Gonzalez, Rene, Kumar, Pallavi, Kuzel, Timothy, Lutzky, Jose, O'Day, Steven, Perry, David, Pecora, Andrew, Puzanov, Igor, Slezak, Karen, Sznol, Mario, Tarhini, Ahmad, Weiss, Geoffrey

المساهمون: Laboratory of Molecullar and Cellular Therapy, Laboratory for Medical and Molecular Oncology, Clinical sciences

المصدر: The New England journal of medicine. 372(26)

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Skin Neoplasms, Adolescent, Programmed Cell Death 1 Receptor, Medizin, Phases of clinical research, Ipilimumab, Antineoplastic Agents, Pembrolizumab, Antibodies, Monoclonal, Humanized, Gastroenterology, Young Adult, Internal medicine, medicine, Humans, Adverse effect, Melanoma, Survival analysis, Aged, Aged, 80 and over, business.industry, Hazard ratio, Antibodies, Monoclonal, General Medicine, Middle Aged, medicine.disease, Survival Analysis, Surgery, Female, Talimogene laherparepvec, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::253c3a098f8b65fc28937f4824ea480cTest
https://pubmed.ncbi.nlm.nih.gov/25963092Test

المؤلفون: Victoria Atkinson, Céleste Lebbé, Jessica C. Hassel, Catalin Mihalcioiu, Cornelia Mauch, Ewa Kalinka-Warzocha, Ian M. Waxman, Ana Arance, Piotr Rutkowski, Kerry J. Savage, Vanna Chiarion-Sileni, Caroline Dutriaux, Micaela Hernberg, Abstr Act, Laurent Mortier, Catriona M. McNeil, Brian Sharkey, Caroline Robert, Dirk Schadendorf, Michele Maio, Christine Horak, Georgina V. Long, Lotta Lundgren-Eriksson, Benjamin Brady, Helen Gogas, Francesco Cognetti, Henrik Schmidt, Paolo A. Ascierto, Julie Charles

المصدر: Robert, C, Long, G V, Brady, B, Dutriaux, C, Maio, M, Mortier, L, Hassel, J C, Rutkowski, P, McNeil, C, Kalinka-Warzocha, E, Savage, K J, Hernberg, M M, Lebbé, C, Charles, J, Mihalcioiu, C, Chiarion-Sileni, V, Mauch, C, Cognetti, F, Arance, A, Schmidt, H, Schadendorf, D, Gogas, H, Lundgren-Eriksson, L, Horak, C, Sharkey, B, Waxman, I M, Atkinson, V & Ascierto, P A 2015, ' Nivolumab in previously untreated melanoma without BRAF mutation ', The New England Journal of Medicine, vol. 372, no. 4, pp. 320-30 . https://doi.org/10.1056/NEJMoa1412082Test
New England Journal of Medicine; 372(4), pp 320-330 (2015)

مصطلحات موضوعية: Adult, Male, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, Adolescent, Dacarbazine, Programmed Cell Death 1 Receptor, Medizin, Phases of clinical research, Ipilimumab, Antineoplastic Agents, Pembrolizumab, ipilimumab-refractory metastatic melanoma, Gastroenterology, Disease-Free Survival, Young Adult, Double-Blind Method, Nivolumab, melanoma, ipilimumab-refractory metastatic melanoma, Internal medicine, Medicine, Humans, Survival rate, Melanoma, Aged, Aged, 80 and over, business.industry, Hazard ratio, Antibodies, Monoclonal, General Medicine, Middle Aged, medicine.disease, Surgery, Survival Rate, Nivolumab, Cancer and Oncology, Female, business, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07253c758028e0b62a420832a391b6ecTest
https://pubmed.ncbi.nlm.nih.gov/25511188Test

المؤلفون: Jason Gotlib, Charles L. Sawyers, Markus G. Manz, James L. Zehnder, Manja Muijtjens, Catriona Jamieson, Scott J. Dylla, Carol D. Jones, Armand Keating, Kevin Li, Irving L. Weissman, Laurie Ailles

المصدر: The New England journal of medicine. 351(7)

مصطلحات موضوعية: Adult, Male, Myeloid, Lymphoid Enhancer-Binding Factor 1, Fusion Proteins, bcr-abl, Antineoplastic Agents, Biology, Piperazines, Colony-Forming Units Assay, hemic and lymphatic diseases, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, medicine, Humans, RNA, Neoplasm, Progenitor cell, beta Catenin, Aged, Microscopy, Confocal, Reverse Transcriptase Polymerase Chain Reaction, Macrophages, General Medicine, Middle Aged, medicine.disease, Hematopoietic Stem Cells, DNA-Binding Proteins, Leukemia, Haematopoiesis, Cytoskeletal Proteins, medicine.anatomical_structure, Imatinib mesylate, Pyrimidines, Drug Resistance, Neoplasm, Catenin, Immunology, Benzamides, Cancer research, Imatinib Mesylate, Trans-Activators, Female, Stem cell, Blast Crisis, Lymphoid enhancer-binding factor 1, Granulocytes, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f8a745cf9586203772b524a0e674c27Test
https://pubmed.ncbi.nlm.nih.gov/15306664Test

المؤلفون: Keith T, Flaherty, Caroline, Robert, Peter, Hersey, Paul, Nathan, Claus, Garbe, Mohammed, Milhem, Lev V, Demidov, Jessica C, Hassel, Piotr, Rutkowski, Peter, Mohr, Reinhard, Dummer, Uwe, Trefzer, James M G, Larkin, Jochen, Utikal, Brigitte, Dreno, Marta, Nyakas, Mark R, Middleton, Jürgen C, Becker, Michelle, Casey, Laurie J, Sherman, Frank S, Wu, Daniele, Ouellet, Anne-Marie, Martin, Kiran, Patel, Dirk, Schadendorf, Mary, Richardson

المصدر: The New England journal of medicine. 367(2)

مصطلحات موضوعية: Oncology, Adult, Male, Proto-Oncogene Proteins B-raf, medicine.medical_specialty, Pyridones, Dacarbazine, MAP Kinase Kinase 2, Medizin, MAP Kinase Kinase 1, Antineoplastic Agents, Kaplan-Meier Estimate, Pyrimidinones, Disease-Free Survival, chemistry.chemical_compound, Young Adult, Internal medicine, medicine, Humans, Vemurafenib, Melanoma, Protein Kinase Inhibitors, Aged, Trametinib, Cobimetinib, Aged, 80 and over, business.industry, MEK inhibitor, Hazard ratio, Dabrafenib, General Medicine, Middle Aged, medicine.disease, Surgery, Intention to Treat Analysis, chemistry, Mutation, Female, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::778f247f586f7abe700c37ec7f75715aTest
http://ora.ox.ac.uk/objects/uuid:17a4cd0c-72ea-46f7-ab36-457c375b3557Test

المؤلفون: David Smith, Julie R. Brahmer, Leora Horn, F. Stephen Hodi, Mario Sznol, Lieping Chen, Georgia Kollia, Drew M. Pardoll, Jon M. Wigginton, Alan J. Korman, Shruti Agrawal, David F. McDermott, Charles G. Drake, Janis M. Taube, Scott J. Antonia, Robert A. Anders, Jeffrey A. Sosman, Richard D. Carvajal, Ashok Kumar Gupta, William H. Sharfman, Haiying Xu, David R. Spigel, Scott N. Gettinger, Michael B. Atkins, Maria Jure-Kunkel, Dan McDonald, Philip D. Leming, Suzanne L. Topalian, Tracee L. McMiller, John D. Powderly

المصدر: The New England journal of medicine. 366(26)

مصطلحات موضوعية: Oncology, Adult, Male, medicine.medical_specialty, Colorectal cancer, Programmed Cell Death 1 Receptor, Ipilimumab, Antineoplastic Agents, Pembrolizumab, Ligands, Article, Avelumab, Prostate cancer, Internal medicine, Carcinoma, Non-Small-Cell Lung, Neoplasms, medicine, Humans, Lung cancer, Carcinoma, Renal Cell, Melanoma, Dose-Response Relationship, Drug, business.industry, Cancer, Antibodies, Monoclonal, Prostatic Neoplasms, General Medicine, medicine.disease, Nivolumab, Female, business, Colorectal Neoplasms, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71942b551cfbc7e66a3ad4a4a5eb8446Test
https://pubmed.ncbi.nlm.nih.gov/25765212Test