Trends in attention-deficit hyperactivity disorder medication use: a retrospective observational study using population-based databases
| العنوان: | Trends in attention-deficit hyperactivity disorder medication use: a retrospective observational study using population-based databases |
|---|---|
| المؤلفون: | Shahram Bahmanyar, Jaana E. Martikainen, David Coghill, Esther W. Chan, Chien Chou Su, Elizabeth E. Roughead, Edward Chia Cheng Lai, Virginia Pate, Helga Zoega, Nicole L. Pratt, Kenneth K.C. Man, Dolores Montero, Anton Pottegård, Yea Huei Kao-Yang, Patrick Ip, Til Stürmer, Ian C. K. Wong, Kiyoshi Kubota, Kari Furu, Anke Neumann, Sudha R. Raman, Nicholas Moore, Diego Macías Saint-Gerons, Miriam C.J.M. Sturkenbroom, Anick Bérard, Hidefumi Nakamura, Scott Bilder, Greta A. Bushnell, Helle Kieler, Géric Maura, Takoua Boukhris, Stephen Crystal, Øystein Karlstad |
| المساهمون: | Raman, Sudha R, Man, Kenneth KC, Bahmanyar, Shahram, Berard, Anick, Pratt, Nicole L, Roughead, Elizabeth E, Wong, Ian CK, Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Medical Informatics |
| المصدر: | The Lancet. Psychiatry The Lancet. Psychiatry, Elsevier, 2018, 5 (10), pp.824-835. ⟨10.1016/s2215-0366(18)30293-1⟩ LANCET PSYCHIATRY, 5(10), 824-835. Elsevier Ltd. Raman, S R, Man, K K C, Bahmanyar, S, Berard, A, Bilder, S, Boukhris, T, Bushnell, G, Crystal, S, Furu, K, KaoYang, Y H, Karlstad, Ø, Kieler, H, Kubota, K, Lai, E C C, Martikainen, J E, Maura, G, Moore, N, Montero, D, Nakamura, H, Neumann, A, Pate, V, Pottegård, A, Pratt, N L, Roughead, E E, Macias Saint-Gerons, D, Stürmer, T, Su, C C, Zoega, H, Sturkenbroom, M C J M, Chan, E W, Coghill, D, Ip, P & Wong, I C K 2018, ' Trends in attention-deficit hyperactivity disorder medication use : a retrospective observational study using population-based databases ', The lancet. Psychiatry, vol. 5, no. 10, pp. 824-835 . https://doi.org/10.1016/S2215-0366Test(18)30293-1 |
| بيانات النشر: | Elsevier BV, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, Atomoxetine Hydrochloride, computer.software_genre, 0302 clinical medicine, Prevalence, Practice Patterns, Physicians', Young adult, Child, education.field_of_study, Adrenergic Uptake Inhibitors, Database, Methylphenidate, Middle Aged, Europe, Psychiatry and Mental health, Child, Preschool, Female, medication, mental-disorders, Atomoxetine hydrochloride, medicine.drug, Adult, Asia, Adolescent, Population, MEDLINE, Young Adult, 03 medical and health sciences, medicine, Humans, Attention deficit hyperactivity disorder, education, deficit/hyperactivity disorder, Biological Psychiatry, Retrospective Studies, PharmacoEpi-Drugs, business.industry, Australia, Retrospective cohort study, medicine.disease, United States, 030227 psychiatry, Attention Deficit Disorder with Hyperactivity, Central Nervous System Stimulants, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Observational study, business, computer, 030217 neurology & neurosurgery |
| الوصف: | Summary Background The use of medications to treat attention deficit hyperactivity disorder (ADHD) has increased, but the prevalence of ADHD medication use across different world regions is not known. Our objective was to determine regional and national prevalences of ADHD medication use in children and adults, with a specific focus on time trends in ADHD medication prevalence. Methods We did a retrospective, observational study using population-based databases from 13 countries and one Special Administrative Region (SAR): four in Asia and Australia, two in North America, five in northern Europe, and three in western Europe. We used a common protocol approach to define study populations and parameters similarly across countries and the SAR. Study populations consisted of all individuals aged 3 years or older between Jan 1, 2001, and Dec 31, 2015 (dependent on data availability). We estimated annual prevalence of ADHD medication use with 95% CI during the study period, by country and region and stratified by age and sex. We reported annual absolute and relative percentage changes to describe time trends. Findings 154·5 million individuals were included in the study. ADHD medication use prevalence in 2010 (in children aged 3–18 years) varied between 0·27% and 6·69% in the countries and SAR assessed (0·95% in Asia and Australia, 4·48% in North America, 1·95% in northern Europe, and 0·70% in western Europe). The prevalence of ADHD medication use among children increased over time in all countries and regions, and the absolute increase per year ranged from 0·02% to 0·26%. Among adults aged 19 years or older, the prevalence of any ADHD medication use in 2010 varied between 0·003% and 1·48% (0·05% in Asia and Australia, 1·42% in North America, 0·47% in northern Europe, and 0·03% in western Europe). The absolute increase in ADHD medication use prevalence per year ranged from 0·0006% to 0·12%. Methylphenidate was the most commonly used ADHD medication in most countries. Interpretation Using a common protocol and data from 13 countries and one SAR, these results show increases over time but large variations in ADHD medication use in multiple regions. The recommendations of evidence-based guidelines need to be followed consistently in clinical practice. Further research is warranted to describe the safety and effectiveness of ADHD medication in the short and long term, and to inform evidence-based guidelines, particularly in adults. Funding None |
| وصف الملف: | application/pdf |
| تدمد: | 2215-0366 2215-0374 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2135a3573585bec62f8dc63d50f2b674Test https://doi.org/10.1016/s2215-0366Test(18)30293-1 |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....2135a3573585bec62f8dc63d50f2b674 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22150366 22150374 |
|---|