دورية
Associations between C-reactive protein, coronary artery calcium, and cardiovascular events: implications for the JUPITER population from MESA, a population-based cohort study
| العنوان: | Associations between C-reactive protein, coronary artery calcium, and cardiovascular events: implications for the JUPITER population from MESA, a population-based cohort study |
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| المؤلفون: | Blaha, Michael J, Budoff, Matthew J, DeFilippis, Andrew P, Blankstein, Ron, Rivera, Juan J, Agatston, Arthur, O'Leary, Daniel H, Lima, Joao, Blumenthal, Roger S, Nasir, Khurram |
| المصدر: | The Lancet; August 2011, Vol. 378 Issue: 9792 p684-692, 9p |
| مستخلص: | The JUPITER trial showed that some patients with LDL-cholesterol concentrations less than 3·37 mmol/L (<130 mg/dL) and high-sensitivity C-reactive protein (hsCRP) concentrations of 2 mg/L or more benefit from treatment with rosuvastatin, although absolute rates of cardiovascular events were low. In a population eligible for JUPITER, we established whether coronary artery calcium (CAC) might further stratify risk; additionally we compared hsCRP with CAC for risk prediction across the range of low and high hsCRP values. |
| قاعدة البيانات: | Supplemental Index |
| تدمد: | 01406736 1474547X |
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| DOI: | 10.1016/S0140-6736(11)60784-8 |