Antibiotic or silver versus standard ventriculoperitoneal shunts (BASICS): a multicentre, single-blinded, randomised trial and economic evaluation

التفاصيل البيبلوغرافية
العنوان: Antibiotic or silver versus standard ventriculoperitoneal shunts (BASICS): a multicentre, single-blinded, randomised trial and economic evaluation
المؤلفون: Mallucci, Conor L, Jenkinson, Michael D, Conroy, Elizabeth J, Hartley, John C, Brown, Michaela, Dalton, Joanne, Kearns, Tom, Moitt, Tracy, Griffiths, Michael J, Culeddu, Giovanna, Solomon, Tom, Hughes, Dyfrig, Gamble, Carrol, Pettorini, Benedetta, Parks, Christopher, Sinha, Ajay, van Tonder, Libby, Foster, Mitchel T, McMahon, Catherine, Buxton, Neil, Chavredakis, Emmanuel, Brodbelt, Andrew R, Lawson, David DA, Eldridge, Paul R, Farah, Jibril O, Zakaria, Rasheed, Geraint, Sunderland, Solanki, Guirish, Rodrigues, Desiderio, Edwards, Richard, Williams, Adam, Garnett, Matthew, Kolias, Angelos, Hutchinson, Peter JA, Caldwell, Karen, Tarantino, Silvia, Leach, Paul, Zaben, Malik, Zilani, Gulam, Shastin, Dmitri, Merola, Joseph, Hussain, Rahim, Vemaraju, Ravindra, Selezneva, Liudmila, Radford, Georgina, Lloyd, Nadine, Crimmins, Darach, Caird, John, Sayar, Maria N, O'Mahoney, Noelle, Thompson, Dominic, Aquilina, Kristian, James, Gregory, Strachan, Roger, Mukerji, Nitin, Zebain, Bassel, Thakur, Bhaskar, Dickson, Holly, Nsirim, Eniola, Adebayo, Adedamola, Goodden, John, Deniz, Kenan, Clarke, Janet, Kambafwile, Mary, Anderson, Ian, Chave-Cox, Rebecca, Sheik, Asim, Mathew, Ryan, Richards, Oliver, Mukherjee, Soumya, Chumas, Paul, Tyagi, Atul, Sikakumar, Gnanamurthy, Toma, Admed, D'Antona, Linda, Watkins, Laurence, Thorne, Lewis, Craven, Claudia, Bassen, Vanessa, Holliman, Damien, Coulter, Ian, Macarthur, Donald, Cartmill, Maria, Howarth, Simon, Smith, Stuart, Javed, Shazia, Kamaly, Ian, Ramirez, Roberto, King, Andrew, Nadig, Ardash, Thorne, John, Ushewokunze, Shungu, Sinha, Saurabh, Zaki, Hesham, McMullan, John, Bulters, Diederik, Waters, Ryan, Zilidis, George, Roach, Joy, Sadek, Ahmed, Holton, Patrick, Zolnourian, Ardalan, Chakraborty, Aabir, Kandasamy, Jothy, Hughes, Mark, Brennan, Paul M
المصدر: The Lancet; October-November 2019, Vol. 394 Issue: 10208 p1530-1539, 10p
مستخلص: Insertion of a ventriculoperitoneal shunt for hydrocephalus is one of the commonest neurosurgical procedures worldwide. Infection of the implanted shunt affects up to 15% of these patients, resulting in prolonged hospital treatment, multiple surgeries, and reduced cognition and quality of life. Our aim was to determine the clinical and cost-effectiveness of antibiotic (rifampicin and clindamycin) or silver shunts compared with standard shunts at reducing infection.
قاعدة البيانات: Supplemental Index
الوصف
تدمد:01406736
1474547X
DOI:10.1016/S0140-6736(19)31603-4