المؤلفون: Joanna Parkinson, David W. Boulton, Weifeng Tang, Robert C. Penland, Bengt Hamrén, Melin J, Dinko Rekić

المصدر: The Journal of Clinical Pharmacology. 62:1227-1235

مصطلحات موضوعية: Adult, Blood Glucose, Male, endocrine system diseases, Pharmacology, chemistry.chemical_compound, Clinical Trials, Phase II as Topic, Glucosides, Pharmacokinetics, Humans, Hypoglycemic Agents, Medicine, Pharmacology (medical), Benzhydryl Compounds, Dapagliflozin, Dose-Response Relationship, Drug, business.industry, nutritional and metabolic diseases, Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 1, Clinical Trials, Phase III as Topic, Diabetes Mellitus, Type 2, chemistry, Female, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b579476a26ab5879587b6096ae6b72Test
https://doi.org/10.1002/jcph.2062Test

المؤلفون: Celine Bolwerk, Cecile Magis-Escurra, Wouter Hoefsloot, Laurens F. M. Verscheijden, Arjan van Laarhoven, David M. Burger, Jakko van Ingen, Jan B. Koenderink, Frans G. M. Russel, Reinout van Crevel, Rob E. Aarnoutse, Martin J. Boeree, Rovina Ruslami, Petra H.H. van den Broek, Carlijn H. C. Litjens, Lindsey H.M. te Brake, Elin M. Svensson, Jeroen J. M. W. van den Heuvel, Saskia Kuipers, Rick Greupink

المصدر: Journal of Clinical Pharmacology and Journal of New Drugs, 62, 3, pp. 385-396
Journal of Clinical Pharmacology and Journal of New Drugs, 62, 385-396

مصطلحات موضوعية: Adult, Drug, drug-drug interactions, Tuberculosis, media_common.quotation_subject, Moxifloxacin, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], Pharmacokinetic modeling, Antitubercular Agents, lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Pharmacology and Toxicology, Pharmacology, Multiple dose, Models, Biological, physiologically based pharmacokinetics, Pharmaceutical Sciences, Pharmacokinetics, In vivo, medicine, Humans, Pharmacology (medical), ATP Binding Cassette Transporter, Subfamily B, Member 1, Glucuronosyltransferase, Child, media_common, business.industry, modeling, Farmakologi och toxikologi, Farmaceutiska vetenskaper, bacterial infections and mycoses, medicine.disease, Multidrug Resistance-Associated Protein 2, HEK293 Cells, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4], tuberculosis, Area Under Curve, Drug Therapy, Combination, Rifampin, moxifloxacin, business, Rifampicin, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e627cee41f24ef6bdaceab6a4f0d8bTest
https://doi.org/10.1002/jcph.1972Test

المؤلفون: Bogusław Okopień, Robert Krysiak, Marcin Basiak, Witold Szkróbka

المصدر: The Journal of Clinical Pharmacology. 61:1165-1173

مصطلحات موضوعية: Adult, Blood Glucose, Male, medicine.medical_specialty, Homocysteine, Blood Pressure, 030226 pharmacology & pharmacy, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Insulin resistance, Internal medicine, medicine, Humans, Glucose homeostasis, Body Weights and Measures, Testosterone, Pharmacology (medical), Telmisartan, Androstenedione, Pharmacology, business.industry, Siblings, Cardiometabolic Risk Factors, Middle Aged, medicine.disease, Lipids, Polycystic ovary, C-Reactive Protein, Blood pressure, Endocrinology, chemistry, Cardiovascular Diseases, 030220 oncology & carcinogenesis, Hypertension, Uric acid, Female, Insulin Resistance, business, Angiotensin II Type 1 Receptor Blockers, Polycystic Ovary Syndrome, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6b01f746e8438cdc70a2fe3f2f9e035Test
https://doi.org/10.1002/jcph.1872Test

المؤلفون: David Carter, Akshanth R. Polepally, Juki Ng, Ahmed Salem, Mohamad Shebley, Matthew B. Dufek, Apurvasena Parikh, Nael M. Mostafa, Kent Kamradt

المصدر: Journal of Clinical Pharmacology

مصطلحات موضوعية: Male, endometriosis, Hydrocarbons, Fluorinated, Digoxin, Pharmacology, 030226 pharmacology & pharmacy, 0302 clinical medicine, drug‐drug interaction, GnRH antagonist, ATP Binding Cassette Transporter, Subfamily G, Member 2, Cytochrome P-450 CYP3A, CYP3A, Drug Interactions, Pharmacology (medical), Cytochrome P-450 CYP2B6 Inducers, Liver-Specific Organic Anion Transporter 1, Area under the curve, Cytochrome P-450 CYP3A Inducers, Middle Aged, Healthy Volunteers, Neoplasm Proteins, 030220 oncology & carcinogenesis, Female, Ketoconazole, medicine.drug, Adult, Cytochrome P-450 CYP2C9 Inhibitors, Uterine fibroids, Drug Administration Schedule, Solute Carrier Organic Anion Transporter Family Member 1B3, Young Adult, 03 medical and health sciences, medicine, Humans, Rosuvastatin, ATP Binding Cassette Transporter, Subfamily B, Member 1, uterine fibroids, Bupropion, business.industry, Norethindrone Acetate, elagolix, medicine.disease, Cytochrome P-450 CYP2B6, Pyrimidines, Premenopause, Cytochrome P-450 CYP3A Inhibitors, Midazolam, business, Receptors, LHRH

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622863b364cfd49f6d03128b0e958c96Test
https://doi.org/10.1002/jcph.1689Test

المؤلفون: Kenju Shimomura, Sho Shimazaki, Shingen Misaka, Junko Kuroda

المصدر: The Journal of Clinical Pharmacology. 61:799-805

مصطلحات موضوعية: Adult, Male, food.ingredient, genetic structures, Adrenergic beta-Antagonists, Urine, Pharmacology, 030226 pharmacology & pharmacy, Grapefruit juice, Young Adult, 03 medical and health sciences, 0302 clinical medicine, food, Pharmacokinetics, Nadolol, In vivo, medicine, Humans, Drug Interactions, Pharmacology (medical), ATP Binding Cassette Transporter, Subfamily B, Member 1, Chemistry, Middle Aged, Drug interaction, Bioavailability, Area Under Curve, 030220 oncology & carcinogenesis, Renal physiology, Female, Itraconazole, Rifampin, Citrus paradisi, Half-Life, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92dacebf10f9ec03846a0e10b45e7a79Test
https://doi.org/10.1002/jcph.1812Test

المؤلفون: Michael S. Gordon, Andrew J. Wagner, Fumiaki Kobayashi, Hamim Zahir, Cynthia Zamora, Roohi Gajee, Jonathan Greenberg, Qiang Wang, Hani M. Babiker

المصدر: Journal of Clinical Pharmacology

مصطلحات موضوعية: Adult, Male, Digoxin, cytochrome P450, CYP3A, Aminopyridines, CYP2C19, Pharmacology, 030226 pharmacology & pharmacy, 03 medical and health sciences, 0302 clinical medicine, Tolbutamide, Pharmacokinetics, P‐glycoprotein, medicine, Cytochrome P-450 CYP3A, Humans, Drug Interactions, Pyrroles, Pharmacology (medical), ATP Binding Cassette Transporter, Subfamily B, Member 1, CYP2C9, Omeprazole, Aged, Cytochrome P-450 CYP2C9, drug interaction, Cross-Over Studies, Chemistry, Middle Aged, Drug interaction, Cytochrome P-450 CYP2C19, Area Under Curve, 030220 oncology & carcinogenesis, Female, pharmacokinetics, pexidartinib, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::955ef7d956c23011d0f30d246a5ea56aTest
https://doi.org/10.1002/jcph.1734Test

المؤلفون: Takuro Endo, Hiroo Takeda, Asuka Kawai, Takao Furihata, Kaoru Kobayashi, Yoshikazu Abe

المصدر: The Journal of Clinical Pharmacology. 60:1314-1323

مصطلحات موضوعية: Adult, Male, Pyrrolidines, Abcg2, Itraconazole, Metabolite, Cmax, Administration, Oral, Drug Elimination Routes, Urine, Pharmacology, 030226 pharmacology & pharmacy, Permeability, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Asian People, Pharmacokinetics, medicine, ATP Binding Cassette Transporter, Subfamily G, Member 2, Cytochrome P-450 CYP3A, Humans, Drug Interactions, Pharmacology (medical), ATP Binding Cassette Transporter, Subfamily B, Member 1, Thyrotropin-Releasing Hormone, Oxazolidinones, biology, CYP3A4, Cytochrome P450, Biological Transport, Healthy Volunteers, Hormones, Neoplasm Proteins, chemistry, Area Under Curve, 030220 oncology & carcinogenesis, biology.protein, Cytochrome P-450 CYP3A Inhibitors, Caco-2 Cells, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::445b1ecb7c5a250abf7dc69d202fe858Test
https://doi.org/10.1002/jcph.1628Test

المؤلفون: Susan Petusky, Brad Yuska, Zhinyin Xun, Gongfu Zhou, Nithya Srinivas, April M. Barbour, Thomas Marbury, Naresh Punwani, Xuejun Chen, Noam Epstein, Swamy Yeleswaram

المصدر: Journal of Clinical Pharmacology

مصطلحات موضوعية: renal impairment, Adult, Male, medicine.medical_specialty, Acetonitriles, graft‐versus‐host disease, medicine.medical_treatment, itacitinib, Urology, Urine, Kidney, 030226 pharmacology & pharmacy, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Renal Dialysis, Dialysis Solutions, medicine, Humans, NON COVID RELATED ARTICLES, Pyrroles, Pharmacology (medical), Renal Insufficiency, Dosing, Adverse effect, Janus kinase inhibitor, Protein Kinase Inhibitors, Dialysis, Aged, Pharmacology, business.industry, Blood Proteins, Janus Kinase 1, Middle Aged, Confidence interval, Special Populations, Renal Elimination, Pyrimidines, Area Under Curve, 030220 oncology & carcinogenesis, dialysis, Pyrazoles, Female, Hemodialysis, business, pharmacokinetics, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed82052940b518d1ca6844fcdc4e898bTest
https://doi.org/10.1002/jcph.1601Test

المؤلفون: Patrick Martin, Kenneth C. Lasseter, Katarina Ilic, Joseph Murphy, Ivy H. Song

المصدر: Journal of Clinical Pharmacology

مصطلحات موضوعية: Adult, Male, Digoxin, CYP2D6, maribavir, Genotype, Cmax, Pharmacology, Antiviral Agents, 030226 pharmacology & pharmacy, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Dextrorphan, P‐glycoprotein, medicine, Humans, Drug Interactions, Pharmacology (medical), ATP Binding Cassette Transporter, Subfamily B, Member 1, cytochrome P450 2D6, dextromethorphan, business.industry, Maribavir, Dextromethorphan, Middle Aged, Healthy Volunteers, Confidence interval, Cytochrome P-450 CYP2D6, 030220 oncology & carcinogenesis, Cytomegalovirus Infections, Benzimidazoles, Female, Ribonucleosides, business, pharmacokinetics, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c66d3450457c23c2787f47f573b9d1dTest
https://doi.org/10.1002/jcph.1504Test

المؤلفون: Michelle Liu, Aniwaa Owusu Obeng

المصدر: The Journal of Clinical Pharmacology. 60:429-431

مصطلحات موضوعية: Adult, Sphingosine 1 Phosphate Receptor Modulators, Pharmacology, Genetics, Clinical Trials as Topic, Multiple Sclerosis, Genotype, business.industry, Black or African American, chemistry.chemical_compound, Siponimod, chemistry, Benzyl Compounds, Prevalence, Azetidines, Humans, Medicine, Genetic Predisposition to Disease, Pharmacology (medical), Allele, business, CYP2C9, Alleles, Cytochrome P-450 CYP2C9

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2bbe36feea2038a36b80456aea9c54fTest
https://doi.org/10.1002/jcph.1546Test