COVID-19 Hospitalization in Adults with Type 1 Diabetes: Results from the T1D Exchange Multi-Center Surveillance Study
| العنوان: | COVID-19 Hospitalization in Adults with Type 1 Diabetes: Results from the T1D Exchange Multi-Center Surveillance Study |
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| المؤلفون: | Michael Tansey, Devin Steenkamp, Shivani Agarwal, Catherina T. Pinnaro, Irl B. Hirsch, Nudrat Noor, Grenye O’Malley, Alissa J. Roberts, Grazia Aleppo, Marina Basina, Lauren Golden, Priyanka Mathias, Sarit Polsky, Ilona Lorincz, Osagie Ebekozien, Marisa E Desimone, Carol J. Levy, Francesco Vendrame |
| المصدر: | The Journal of Clinical Endocrinology and Metabolism |
| بيانات النشر: | Oxford University Press, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Pediatrics, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, 030209 endocrinology & metabolism, Context (language use), Comorbidity, 030204 cardiovascular system & hematology, Logistic regression, Biochemistry, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Endocrinology, Diabetes mellitus, Internal medicine, medicine, Humans, Pandemics, Glycemic, Aged, Retrospective Studies, Aged, 80 and over, Type 1 diabetes, Clinical Research Article, business.industry, SARS-CoV-2, Biochemistry (medical), COVID-19, Middle Aged, medicine.disease, Prognosis, Obesity, United States, Hospitalization, Cross-Sectional Studies, Diabetes Mellitus, Type 1, Treatment Outcome, Population Surveillance, Population study, Observational study, Female, business, AcademicSubjects/MED00250 |
| الوصف: | Context Diabetes mellitus is associated with increased COVID-19 morbidity and mortality, but there are few data focusing on outcomes in people with type 1 diabetes. Objective The objective of this study was to analyze characteristics of adults with type 1 diabetes for associations with COVID-19 hospitalization. Design An observational multisite cross-sectional study was performed. Diabetes care providers answered a 33-item questionnaire regarding demographics, symptoms, and diabetes- and COVID-19-related care and outcomes. Descriptive statistics were used to describe the study population, and multivariate logistic regression models were used to analyze the relationship between glycated hemoglobin (HbA1c), age, and comorbidities and hospitalization. Setting Cases were submitted from 52 US sites between March and August 2020. Patients or Other Participants Adults over the age of 19 with type 1 diabetes and confirmed COVID-19 infection were included. Interventions None. Main Outcome Measures Hospitalization for COVID-19 infection. Results A total of 113 cases were analyzed. Fifty-eight patients were hospitalized, and 5 patients died. Patients who were hospitalized were more likely to be older, to identify as non-Hispanic Black, to use public insurance, or to have hypertension, and less likely to use continuous glucose monitoring or insulin pumps. Median HbA1c was 8.6% (70 mmol/mol) and was positively associated with hospitalization (odds ratio 1.42, 95% confidence interval 1.18-1.76), which persisted after adjustment for age, sex, race, and obesity. Conclusions Baseline glycemic control and access to care are important modifiable risk factors which need to be addressed to optimize care of people with type 1 diabetes during the worldwide COVID-19 pandemic. |
| اللغة: | English |
| تدمد: | 1945-7197 0021-972X |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb8c0d1f02209fb8a4705bf41c2bdc4Test http://europepmc.org/articles/PMC7717244Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....8cb8c0d1f02209fb8a4705bf41c2bdc4 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19457197 0021972X |
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