المؤلفون: Hong Soon Kang, Anton M. Jetten, Kevin Gerrish, Amir Aghajanian, Ju Youn Beak, Brian C. Jensen, Seok Jae Hong, Wei Huang, Rishi Deshmukh, Nishi Kadakia

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: HIF-1α, hypoxia-inducible factor-1α, Caveolin 3, PINK1, PTEN-induced putative kinase 1, LC3B-II, microtubule-associated protein light chain beta 3-II, Mitochondrion, Biochemistry, CMKO, cardiomyocyte-specific RORα KO, JC-1, 5, 5′, 6, 6′-tetrachloro-1, 1′, 3, 3′-tetraethylbenzimidazolylcarbocyanine iodide, Mitochondria, Heart, Mice, Mitophagy, OCR, oxygen consumption rate, Myocytes, Cardiac, Cav-3, caveolin-3, mt-Keima, mitochondrial-targeted Keima, shCtrl, scrambled shRNA, Cardioprotection, Gene knockdown, LDH, lactate dehydrogenase, Bnip3, BCL2 interacting protein 3, HRP, horseradish peroxidase, Nuclear Receptor Subfamily 1, Group F, Member 1, shRORα, shRNA against RORα, Cell biology, ChIP, chromatin immunoprecipitation, BFA1, bafilomycin A1, SDH, succinate dehydrogenase, NRVMs, neonatal rat ventricular myocytes, qRT-PCR, quantitative RT-PCR, Research Article, caveolin-3, mPTP, mitochondrial permeability transition pore, cardiomyocyte mitochondrial physiology, Biology, ROS, reactive oxygen species, Downregulation and upregulation, Animals, TEM, transmission electron microscopy, Molecular Biology, ROR, retinoic acid–related orphan nuclear receptor, Ang II, angiotensin II, hypoxia, Autophagy, Cell Biology, RAR-related orphan receptor alpha (ROR-alpha), Nuclear receptor, Hsp60, heat shock protein 60, PFA, paraformaldehyde

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47cc243bde3123b1ebf3e9dc15c170f2Test
http://europepmc.org/articles/PMC8626585Test

المؤلفون: Richard L. Gallo, Tatsuya Dokoshi, Alan M. O’Neill, Elizabeth Wei Chia Luo, Nikhil Nitin Kulkarni, Gerard C. L. Wong

المصدر: The Journal of Biological Chemistry
The Journal of biological chemistry, vol 297, iss 1

مصطلحات موضوعية: 0301 basic medicine, Transcription, Genetic, medicine.medical_treatment, Inbred C57BL, Biochemistry, Medical and Health Sciences, Cathelicidin, Mice, Double-Stranded, antimicrobial peptides, SR, scavenger receptor, Receptors, cathelicidin, Innate, Receptor, GAS, group A Streptococcus, Receptors, Scavenger, Alanine, LDH, lactate dehydrogenase, Chemistry, LL-37, 37-amino acid peptide, UCSD, University of California, San Diego, SAXS, small-angle X-ray scattering, interferon, Alanine scanning, Biological Sciences, Cell biology, IL-6, interleukin 6, Infectious Diseases, LL-34, 34-amino acid peptide, Interferon Type I, qRT-PCR, quantitative RT-PCR, Female, NHEK, normal human epidermal keratinocyte, Transcription, RIGI, retinoic acid–inducible gene I, Research Article, Protein Binding, Signal Transduction, Biochemistry & Molecular Biology, skin, HDMEC, human dermal microvascular endothelial cell, MIC, minimum inhibitory concentration, Antimicrobial peptides, I20P, proline at isoleucine position 20, IRF7, interferon regulatory factor 7, Biophysical Phenomena, Scavenger, MAVS, mitochondrial antiviral signaling, Cell Line, 03 medical and health sciences, Structure-Activity Relationship, Genetic, Cathelicidins, GO, Gene Ontology, medicine, Genetics, Animals, Humans, Amino Acid Sequence, Molecular Biology, RNA, Double-Stranded, Inflammation, Innate immune system, 030102 biochemistry & molecular biology, Cell Membrane, Immunity, RNA, Cell Biology, cytokines, Immunity, Innate, Toll-Like Receptor 3, Mice, Inbred C57BL, 030104 developmental biology, Emerging Infectious Diseases, Gene Expression Regulation, Chemical Sciences, TBK1, TANK-binding kinase 1, Mutation, Nucleic acid, Antimicrobial Cationic Peptides

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7653124affc7f3c4f58a75aed7ae4eb7Test
http://europepmc.org/articles/PMC8214221Test

المؤلفون: Yoshitake Cho, Anne N. Murphy, Alex Liang, Shamim Khosrowjerdi, Oliver R. Zhang, Robert S. Ross, Aleksander Andreyev, Kayla Lam, Ruixia Li, Shizuko Tachibana, Yoh Arita

المصدر: The Journal of Biological Chemistry
The Journal of biological chemistry, vol 297, iss 1

مصطلحات موضوعية: 0301 basic medicine, mitochondrial biogenesis, ATP5B, Messenger, NCM, neonatal cardiomyocytes, Muscle Proteins, cardiomyocytes, Mitochondrion, PGC-1, PPARgamma coactivator 1, SDHb, succinate dehydrogenase complex iron–sulfur subunit B, Inbred C57BL, Cardiovascular, Biochemistry, Medical and Health Sciences, OxPhos, oxidative phosphorylation, Oxidative Phosphorylation, Mice, Cox, cytochrome c oxidase, oxidative metabolism, Receptors, Myocyte, Protein Isoforms, 2.1 Biological and endogenous factors, OCR, oxygen consumption rate, Perm1, peroxisome proliferator-activated receptor coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator, muscle 1, Aetiology, Organelle Biogenesis, Heart development, LDH, lactate dehydrogenase, Intracellular Signaling Peptides and Proteins, Heart, Biological Sciences, Cell Hypoxia, Cell biology, Mitochondria, Mitochondrial, Heart Disease, 5.1 Pharmaceuticals, medicine.symptom, Development of treatments and therapeutic interventions, Mito, mitochondrial, Cardiac, Transcription, Oxidation-Reduction, Perm1, NDUFS3, NADH dehydrogenase [ubiquinone] iron–sulfur protein 3, Research Article, Programmed cell death, Biochemistry & Molecular Biology, Heart Ventricles, Down-Regulation, ATP5b, ATP synthase F1 subunit beta, Biology, TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling, Promoter Regions, 03 medical and health sciences, H/R, hypoxia-reoxygenation, UQCRC2, ubiquinol-cytochrome C reductase core protein 2, Genetic, Coactivator, medicine, Genetics, COXIV, cytochrome c oxidase subunit IV, Animals, Humans, Molecular Biology, Heart Failure, Myocytes, 030102 biochemistry & molecular biology, Cell Biology, DNA, Hypoxia (medical), Estrogen, Oxygen, ERR, estrogen-related receptor, 030104 developmental biology, Mitochondrial biogenesis, SERCA, Sarco/endoplasmic reticulum Ca2+-ATPase, Protein Biosynthesis, Musculoskeletal, Chemical Sciences, RNA, Transcription Factors

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::352ef9a79b8dfcd8924d67bb08dbe283Test
http://europepmc.org/articles/PMC8214196Test

المؤلفون: Yan Wang, Yalin Wu, Zuguo Liu, Jingmeng Chen, Chao Chen

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Retinal degeneration, STEAP3, six-transmembrane epithelial antigen of prostate 3, genetic structures, STGD1, autosomal recessive Stargardt disease, TFRC, transferrin receptor, ONL, outer nuclear layer, Mitochondrion, medicine.disease_cause, Biochemistry, Photoreceptor cell, Mice, DMT1, Divalent metal transporter 1, GSH, glutathione, Stargardt Disease, oxidative stress, iron metabolism, AMD, age-related macular degeneration, IREB2, Iron-responsive element binding protein 2, POS, photoreceptor outer segments, chemistry.chemical_classification, Deferoxamine mesylate, LDH, lactate dehydrogenase, Chemistry, TEM, transmission electron microscope, lipid peroxidation, LED, light emitting diode, Cell biology, medicine.anatomical_structure, cell death, Retinaldehyde, Photoreceptor Cells, Vertebrate, Research Article, Programmed cell death, macular degeneration, 03 medical and health sciences, ROS, reactive oxygen species, medicine, Animals, Ferroptosis, Molecular Biology, Reactive oxygen species, Retina, 030102 biochemistry & molecular biology, Cell Biology, medicine.disease, all-trans-retinal, photoreceptor, eye diseases, TF, transferrin, Mice, Inbred C57BL, 030104 developmental biology, CP, ceruloplasmin, atRAL, all-trans-retinal, H&E, hematoxylin and eosin, sense organs, FPN, Ferroportin, Reactive Oxygen Species, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e528672cccb4554ebf9c4e807e79212aTest
https://pubmed.ncbi.nlm.nih.gov/33334878Test

المؤلفون: Xenia Schafer, Sergiy M. Nadtochiy, Paul S. Brookes, Joshua Munger, Keith Nehrke, James H. Miller, Dragony Fu

المصدر: The Journal of biological chemistry. 291(38)

مصطلحات موضوعية: 0301 basic medicine, Male, Mutant, Dehydrogenase, Biology, Biochemistry, Malate dehydrogenase, Glutarates, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Malate Dehydrogenase, Lactate dehydrogenase, medicine, Animals, Molecular Biology, 030304 developmental biology, Acidosis, chemistry.chemical_classification, 0303 health sciences, L-Lactate Dehydrogenase, Cell Biology, Metabolism, Hydrogen-Ion Concentration, Isoenzymes, Cytosol, Alcohol Oxidoreductases, 030104 developmental biology, Isocitrate dehydrogenase, Enzyme, chemistry, 030220 oncology & carcinogenesis, Hypoxia-Inducible Factor 1, medicine.symptom, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a369b15b0d271f7a50d09e61fc0124b8Test
https://pubmed.ncbi.nlm.nih.gov/27510037Test

المؤلفون: Chiara Riganti, Manuela Polimeni, Amalia Bosia, Dario Ghigo, Costanzo Costamagna, Elena Gazzano

المصدر: The Journal of biological chemistry. 279(46)

مصطلحات موضوعية: animal diseases, Citric Acid Cycle, pentose phosphate pathway, Dehydrogenase, Pentose phosphate pathway, Glucosephosphate Dehydrogenase, medicine.disease_cause, Biochemistry, Cell Line, chemistry.chemical_compound, Mice, dehydroepiandrosterone, Onium Compounds, Lactate dehydrogenase, diphenyleneiodonium, diphenyliodonium, glucose 6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, reactive oxygen species, malonyldialdehyde, lactate dehydrogenase, glyceraldehyde 3-phosphate dehydrogenase, medicine, Animals, Enzyme Inhibitors, Molecular Biology, L-Lactate Dehydrogenase, Phosphogluconate Dehydrogenase, Biphenyl Compounds, Glyceraldehyde-3-Phosphate Dehydrogenases, Cell Biology, Glutathione, Molecular biology, Citric acid cycle, Oxidative Stress, Glucose, chemistry, Glutathione disulfide, NAD+ kinase, Neuroglia, Oxidation-Reduction, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56fe07c5c147e53e0fb82421a17077e4Test
https://pubmed.ncbi.nlm.nih.gov/15358777Test

المؤلفون: Syeda Maham Mahmood, Shunqian Jin, Vijay P. Singh, Dong Wang, Meena Ananthanaravanan, John F. Eisses, George Perides, Yuhuan Luo, Tanveer A. Javed, Sohail Z. Husain, John A. Williams, Kamaldeen A. Muili, Abrahim I. Orabi, Sheharyar Sarwar, Jeffery D. Molkentin

المصدر: The Journal of biological chemistry. 288(1)

مصطلحات موضوعية: medicine.medical_specialty, Time Factors, medicine.drug_class, Acinar Cells, Biology, Biochemistry, digestive system, Tacrolimus, Bile Acids and Salts, chemistry.chemical_compound, Mice, Cytosol, Internal medicine, Acinar cell, medicine, Animals, Chymotrypsin, Protein Isoforms, Molecular Biology, Egtazic Acid, Pancreas, Pancreatic duct, Bile acid, L-Lactate Dehydrogenase, NFATC Transcription Factors, Calcineurin, NF-kappa B, NFAT, Cell Biology, Taurocholic acid, medicine.anatomical_structure, Endocrinology, chemistry, Pancreatitis, Calcium, Taurolithocholic acid, Taurolithocholic Acid, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a613772fe026a7527e6fdda5ff429bcaTest
https://pubmed.ncbi.nlm.nih.gov/23148215Test

المؤلفون: Rong Meng, Leobaldo Solorzano, Charles P. Scott, Andrew A. Quong, Je-Wook Yu, Christine Juliana, Emad S. Alnemri, Jianghong Wu, Teresa Fernandes-Alnemri, Eicke Latz, Pinaki Datta

المصدر: The Journal of biological chemistry. 285(13)

مصطلحات موضوعية: medicine.drug_class, Immunoblotting, Caspase 1, Anti-Inflammatory Agents, Inflammation, Bone Marrow Cells, IκB kinase, Pharmacology, Biology, Biochemistry, Anti-inflammatory, chemistry.chemical_compound, Mice, Nitriles, medicine, Animals, Humans, Protease inhibitor (pharmacology), Parthenolide, Sulfones, Molecular Biology, Cell Death, L-Lactate Dehydrogenase, Macrophages, NF-kappa B, Inflammasome, Cell Biology, chemistry, medicine.symptom, Signal transduction, Sesquiterpenes, medicine.drug, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1fce605e79687f0d0a2f84fc6c63533Test
https://pubmed.ncbi.nlm.nih.gov/20093358Test

المؤلفون: Tatsuhide Tanaka, Masaki Ueno, Toshihide Yamashita

المصدر: The Journal of biological chemistry. 284(32)

مصطلحات موضوعية: MAPK/ERK pathway, Nervous system, Central Nervous System, Wallerian degeneration, Neurite, Central nervous system, Biology, Biochemistry, Models, Biological, p38 Mitogen-Activated Protein Kinases, Cell Line, Myelin, Mice, Molecular Basis of Cell and Developmental Biology, Phagocytosis, medicine, Animals, Axon, Rats, Wistar, Molecular Biology, Microglia, L-Lactate Dehydrogenase, Brain, Cell Biology, medicine.disease, Axons, Cell biology, Rats, Mice, Inbred C57BL, medicine.anatomical_structure, nervous system, Immunology, Spleen

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c6a9e7ed1b9a07a31f27b2a2ac7b4bTest
https://pubmed.ncbi.nlm.nih.gov/19531468Test

المؤلفون: Anindita, Das, Lei, Xi, Rakesh C, Kukreja

المصدر: The Journal of biological chemistry. 280(13)

مصطلحات موضوعية: Male, DNA, Complementary, Time Factors, Nitric Oxide Synthase Type III, Transcription, Genetic, Cell Survival, Phosphodiesterase Inhibitors, Blotting, Western, bcl-X Protein, Nitric Oxide Synthase Type II, Apoptosis, Nitric Oxide, Piperazines, Sildenafil Citrate, Membrane Potentials, Mice, Necrosis, 3',5'-Cyclic-GMP Phosphodiesterases, In Situ Nick-End Labeling, Animals, Myocytes, Cardiac, Sulfones, Enzyme Inhibitors, Cells, Cultured, DNA Primers, Cyclic Nucleotide Phosphodiesterases, Type 5, Mice, Knockout, Mice, Inbred ICR, Muscle Cells, L-Lactate Dehydrogenase, Caspase 3, Phosphoric Diester Hydrolases, Reverse Transcriptase Polymerase Chain Reaction, Trypan Blue, Carbocyanines, Immunohistochemistry, Mitochondria, Enzyme Activation, Mice, Inbred C57BL, Oxygen, NG-Nitroarginine Methyl Ester, Proto-Oncogene Proteins c-bcl-2, Purines, Caspases, Benzimidazoles, Nitric Oxide Synthase, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::4d1a6a0ddb956c78eb41ec3e4d9ad7c5Test
https://pubmed.ncbi.nlm.nih.gov/15668244Test