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المؤلفون: Hong Soon Kang, Anton M. Jetten, Kevin Gerrish, Amir Aghajanian, Ju Youn Beak, Brian C. Jensen, Seok Jae Hong, Wei Huang, Rishi Deshmukh, Nishi Kadakia
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: HIF-1α, hypoxia-inducible factor-1α, Caveolin 3, PINK1, PTEN-induced putative kinase 1, LC3B-II, microtubule-associated protein light chain beta 3-II, Mitochondrion, Biochemistry, CMKO, cardiomyocyte-specific RORα KO, JC-1, 5, 5′, 6, 6′-tetrachloro-1, 1′, 3, 3′-tetraethylbenzimidazolylcarbocyanine iodide, Mitochondria, Heart, Mice, Mitophagy, OCR, oxygen consumption rate, Myocytes, Cardiac, Cav-3, caveolin-3, mt-Keima, mitochondrial-targeted Keima, shCtrl, scrambled shRNA, Cardioprotection, Gene knockdown, LDH, lactate dehydrogenase, Bnip3, BCL2 interacting protein 3, HRP, horseradish peroxidase, Nuclear Receptor Subfamily 1, Group F, Member 1, shRORα, shRNA against RORα, Cell biology, ChIP, chromatin immunoprecipitation, BFA1, bafilomycin A1, SDH, succinate dehydrogenase, NRVMs, neonatal rat ventricular myocytes, qRT-PCR, quantitative RT-PCR, Research Article, caveolin-3, mPTP, mitochondrial permeability transition pore, cardiomyocyte mitochondrial physiology, Biology, ROS, reactive oxygen species, Downregulation and upregulation, Animals, TEM, transmission electron microscopy, Molecular Biology, ROR, retinoic acid–related orphan nuclear receptor, Ang II, angiotensin II, hypoxia, Autophagy, Cell Biology, RAR-related orphan receptor alpha (ROR-alpha), Nuclear receptor, Hsp60, heat shock protein 60, PFA, paraformaldehyde
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47cc243bde3123b1ebf3e9dc15c170f2Test
http://europepmc.org/articles/PMC8626585Test -
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المؤلفون: Yoshitake Cho, Anne N. Murphy, Alex Liang, Shamim Khosrowjerdi, Oliver R. Zhang, Robert S. Ross, Aleksander Andreyev, Kayla Lam, Ruixia Li, Shizuko Tachibana, Yoh Arita
المصدر: The Journal of Biological Chemistry
The Journal of biological chemistry, vol 297, iss 1مصطلحات موضوعية: 0301 basic medicine, mitochondrial biogenesis, ATP5B, Messenger, NCM, neonatal cardiomyocytes, Muscle Proteins, cardiomyocytes, Mitochondrion, PGC-1, PPARgamma coactivator 1, SDHb, succinate dehydrogenase complex iron–sulfur subunit B, Inbred C57BL, Cardiovascular, Biochemistry, Medical and Health Sciences, OxPhos, oxidative phosphorylation, Oxidative Phosphorylation, Mice, Cox, cytochrome c oxidase, oxidative metabolism, Receptors, Myocyte, Protein Isoforms, 2.1 Biological and endogenous factors, OCR, oxygen consumption rate, Perm1, peroxisome proliferator-activated receptor coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator, muscle 1, Aetiology, Organelle Biogenesis, Heart development, LDH, lactate dehydrogenase, Intracellular Signaling Peptides and Proteins, Heart, Biological Sciences, Cell Hypoxia, Cell biology, Mitochondria, Mitochondrial, Heart Disease, 5.1 Pharmaceuticals, medicine.symptom, Development of treatments and therapeutic interventions, Mito, mitochondrial, Cardiac, Transcription, Oxidation-Reduction, Perm1, NDUFS3, NADH dehydrogenase [ubiquinone] iron–sulfur protein 3, Research Article, Programmed cell death, Biochemistry & Molecular Biology, Heart Ventricles, Down-Regulation, ATP5b, ATP synthase F1 subunit beta, Biology, TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling, Promoter Regions, 03 medical and health sciences, H/R, hypoxia-reoxygenation, UQCRC2, ubiquinol-cytochrome C reductase core protein 2, Genetic, Coactivator, medicine, Genetics, COXIV, cytochrome c oxidase subunit IV, Animals, Humans, Molecular Biology, Heart Failure, Myocytes, 030102 biochemistry & molecular biology, Cell Biology, DNA, Hypoxia (medical), Estrogen, Oxygen, ERR, estrogen-related receptor, 030104 developmental biology, Mitochondrial biogenesis, SERCA, Sarco/endoplasmic reticulum Ca2+-ATPase, Protein Biosynthesis, Musculoskeletal, Chemical Sciences, RNA, Transcription Factors
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::352ef9a79b8dfcd8924d67bb08dbe283Test
http://europepmc.org/articles/PMC8214196Test -
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المؤلفون: Xenia Schafer, Sergiy M. Nadtochiy, Paul S. Brookes, Joshua Munger, Keith Nehrke, James H. Miller, Dragony Fu
المصدر: The Journal of biological chemistry. 291(38)
مصطلحات موضوعية: 0301 basic medicine, Male, Mutant, Dehydrogenase, Biology, Biochemistry, Malate dehydrogenase, Glutarates, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Malate Dehydrogenase, Lactate dehydrogenase, medicine, Animals, Molecular Biology, 030304 developmental biology, Acidosis, chemistry.chemical_classification, 0303 health sciences, L-Lactate Dehydrogenase, Cell Biology, Metabolism, Hydrogen-Ion Concentration, Isoenzymes, Cytosol, Alcohol Oxidoreductases, 030104 developmental biology, Isocitrate dehydrogenase, Enzyme, chemistry, 030220 oncology & carcinogenesis, Hypoxia-Inducible Factor 1, medicine.symptom, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a369b15b0d271f7a50d09e61fc0124b8Test
https://pubmed.ncbi.nlm.nih.gov/27510037Test -
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المؤلفون: Syeda Maham Mahmood, Shunqian Jin, Vijay P. Singh, Dong Wang, Meena Ananthanaravanan, John F. Eisses, George Perides, Yuhuan Luo, Tanveer A. Javed, Sohail Z. Husain, John A. Williams, Kamaldeen A. Muili, Abrahim I. Orabi, Sheharyar Sarwar, Jeffery D. Molkentin
المصدر: The Journal of biological chemistry. 288(1)
مصطلحات موضوعية: medicine.medical_specialty, Time Factors, medicine.drug_class, Acinar Cells, Biology, Biochemistry, digestive system, Tacrolimus, Bile Acids and Salts, chemistry.chemical_compound, Mice, Cytosol, Internal medicine, Acinar cell, medicine, Animals, Chymotrypsin, Protein Isoforms, Molecular Biology, Egtazic Acid, Pancreas, Pancreatic duct, Bile acid, L-Lactate Dehydrogenase, NFATC Transcription Factors, Calcineurin, NF-kappa B, NFAT, Cell Biology, Taurocholic acid, medicine.anatomical_structure, Endocrinology, chemistry, Pancreatitis, Calcium, Taurolithocholic acid, Taurolithocholic Acid, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a613772fe026a7527e6fdda5ff429bcaTest
https://pubmed.ncbi.nlm.nih.gov/23148215Test -
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المؤلفون: Rong Meng, Leobaldo Solorzano, Charles P. Scott, Andrew A. Quong, Je-Wook Yu, Christine Juliana, Emad S. Alnemri, Jianghong Wu, Teresa Fernandes-Alnemri, Eicke Latz, Pinaki Datta
المصدر: The Journal of biological chemistry. 285(13)
مصطلحات موضوعية: medicine.drug_class, Immunoblotting, Caspase 1, Anti-Inflammatory Agents, Inflammation, Bone Marrow Cells, IκB kinase, Pharmacology, Biology, Biochemistry, Anti-inflammatory, chemistry.chemical_compound, Mice, Nitriles, medicine, Animals, Humans, Protease inhibitor (pharmacology), Parthenolide, Sulfones, Molecular Biology, Cell Death, L-Lactate Dehydrogenase, Macrophages, NF-kappa B, Inflammasome, Cell Biology, chemistry, medicine.symptom, Signal transduction, Sesquiterpenes, medicine.drug, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1fce605e79687f0d0a2f84fc6c63533Test
https://pubmed.ncbi.nlm.nih.gov/20093358Test -
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المؤلفون: Tatsuhide Tanaka, Masaki Ueno, Toshihide Yamashita
المصدر: The Journal of biological chemistry. 284(32)
مصطلحات موضوعية: MAPK/ERK pathway, Nervous system, Central Nervous System, Wallerian degeneration, Neurite, Central nervous system, Biology, Biochemistry, Models, Biological, p38 Mitogen-Activated Protein Kinases, Cell Line, Myelin, Mice, Molecular Basis of Cell and Developmental Biology, Phagocytosis, medicine, Animals, Axon, Rats, Wistar, Molecular Biology, Microglia, L-Lactate Dehydrogenase, Brain, Cell Biology, medicine.disease, Axons, Cell biology, Rats, Mice, Inbred C57BL, medicine.anatomical_structure, nervous system, Immunology, Spleen
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c6a9e7ed1b9a07a31f27b2a2ac7b4bTest
https://pubmed.ncbi.nlm.nih.gov/19531468Test -
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المؤلفون: Jun Sakurai, Shinya Hayashi, Masahiro Nagahama, Shinsuke Morimitsu
المصدر: The Journal of biological chemistry. 278(38)
مصطلحات موضوعية: Sucrose, Lysis, Time Factors, medicine.disease_cause, Biochemistry, PC12 Cells, Polyethylene Glycols, chemistry.chemical_compound, Mice, Cricetinae, Chlorocebus aethiops, Lipid raft, Liposome, Cholesterol, Clostridium perfringens beta toxin, COS Cells, Phosphatidylcholines, Efflux, Chlorine, Protein Binding, Bacterial Toxins, Immunoblotting, Molecular Sequence Data, HL-60 Cells, Polyethylene glycol, CHO Cells, Biology, Cell Line, Dogs, Membrane Microdomains, Cell Line, Tumor, medicine, Centrifugation, Density Gradient, Animals, Humans, Amino Acid Sequence, Molecular Biology, Vero Cells, Ions, Dose-Response Relationship, Drug, L-Lactate Dehydrogenase, Toxin, Cell Biology, Protein Structure, Tertiary, Rats, chemistry, Cell culture, Liposomes, Potassium, Calcium, HeLa Cells
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::322a26211b80274c666ffc21e397e9d1Test
https://pubmed.ncbi.nlm.nih.gov/12851396Test -
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المؤلفون: Alan Bohan, Matthew A. Held, Wensheng Chen, Lee A. Denson, James L. Boyer
المصدر: The Journal of biological chemistry. 278(38)
مصطلحات موضوعية: Male, medicine.medical_specialty, medicine.drug_class, medicine.medical_treatment, Blotting, Western, Immunoblotting, Receptors, Cytoplasmic and Nuclear, Enzyme-Linked Immunosorbent Assay, Mice, Transgenic, Biology, Biochemistry, Proinflammatory cytokine, Cell Line, Mice, Necrosis, Cholestasis, Internal medicine, medicine, Animals, Humans, Electrophoretic mobility shift assay, Luciferases, Promoter Regions, Genetic, Molecular Biology, Liver injury, Mice, Knockout, Bile acid, L-Lactate Dehydrogenase, Models, Genetic, Reverse Transcriptase Polymerase Chain Reaction, Tumor Necrosis Factor-alpha, Cell Biology, medicine.disease, Up-Regulation, Mice, Inbred C57BL, medicine.anatomical_structure, Cytokine, Endocrinology, Liver, Hepatocyte, Hepatocytes, Cytokines, Tumor necrosis factor alpha, Multidrug Resistance-Associated Proteins, Protein Binding, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d698d3a89117318677aa92d09f935311Test
https://pubmed.ncbi.nlm.nih.gov/12837754Test -
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المصدر: The Journal of biological chemistry. 277(7)
مصطلحات موضوعية: Blood Glucose, medicine.medical_specialty, Very low-density lipoprotein, Time Factors, Virulence Factors, Bacterial Toxins, Blotting, Western, Exotoxins, Biology, Lipoproteins, VLDL, medicine.disease_cause, Biochemistry, Thiobarbituric Acid Reactive Substances, Microsomal triglyceride transfer protein, Mice, Internal medicine, FLOX, medicine, Concanavalin A, Escherichia coli, Animals, Secretion, Aspartate Aminotransferases, RNA, Messenger, Molecular Biology, Alleles, Oligonucleotide Array Sequence Analysis, ADP Ribose Transferases, Inflammation, Mice, Knockout, L-Lactate Dehydrogenase, Toxin, Alanine Transaminase, Cell Biology, medicine.disease, Blotting, Northern, Mice, Inbred C57BL, Endocrinology, Phenotype, Liver, Immunology, biology.protein, Hepatocytes, Cytokines, Tumor necrosis factor alpha, Lipid Peroxidation, Steatosis, Lipoprotein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab142afcd8e0b5f7ef517c7bd657791eTest
https://pubmed.ncbi.nlm.nih.gov/11739387Test -
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المصدر: The Journal of biological chemistry. 277(5)
مصطلحات موضوعية: Lipopolysaccharides, Male, Programmed cell death, Cell Survival, medicine.medical_treatment, Macrophage-activating factor, Caspase 1, Priming (immunology), Biology, Biochemistry, Mice, Adenosine Triphosphate, medicine, Escherichia coli, Animals, Receptor, Molecular Biology, N-Glycosyl Hydrolases, Cells, Cultured, Plant Proteins, Mice, Knockout, Cell Death, L-Lactate Dehydrogenase, Receptors, Purinergic P2, Macrophages, Cell Biology, Cell biology, Mice, Inbred C57BL, Cytolysis, Cytokine, Mice, Inbred DBA, Ribosome Inactivating Proteins, Type 1, Interleukin 18, Female, Receptors, Purinergic P2X7, Interleukin-1
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::242b5b3e8ab5cb38422a2f7b71c352c6Test
https://pubmed.ncbi.nlm.nih.gov/11706016Test