Temporal variation selects for diet–microbe co-metabolic traits in the gut of Gorilla spp
| العنوان: | Temporal variation selects for diet–microbe co-metabolic traits in the gut of Gorilla spp |
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| المؤلفون: | Ran Blekhman, Manolito Torralba, Monica Carr, Jessica M. Rothman, Juan D. Umaña, Carl J. Yeoman, Klára Vlčková, Karen E. Nelson, Klara J. Petrzelkova, David Modry, Angelique Todd, Andres Gomez, Rebecca M. Stumpf, Brenda A. Wilson, Steven R. Leigh, Bryan A. White |
| المصدر: | The ISME Journal. 10:514-526 |
| بيانات النشر: | Springer Science and Business Media LLC, 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Dietary Fiber, Male, 0301 basic medicine, 030106 microbiology, Zoology, Gorilla, Biology, digestive system, Microbiology, Feces, 03 medical and health sciences, Species Specificity, Microbial ecology, biology.animal, Animals, Ecology, Evolution, Behavior and Systematics, Gorilla gorilla, Bacteria, Ecology, Geomicrobiology, digestive, oral, and skin physiology, Animal Feed, Biological Evolution, Gastrointestinal Microbiome, Gastrointestinal Tract, Microbial genomics, Environmental biotechnology, Female, Original Article, Corrigendum |
| الوصف: | Although the critical role that our gastrointestinal microbes play in host physiology is now well established, we know little about the factors that influenced the evolution of primate gut microbiomes. To further understand current gut microbiome configurations and diet-microbe co-metabolic fingerprints in primates, from an evolutionary perspective, we characterized fecal bacterial communities and metabolomic profiles in 228 fecal samples of lowland and mountain gorillas (G. g. gorilla and G. b. beringei, respectively), our closest evolutionary relatives after chimpanzees. Our results demonstrate that the gut microbiomes and metabolomes of these two species exhibit significantly different patterns. This is supported by increased abundance of metabolites and bacterial taxa associated with fiber metabolism in mountain gorillas, and enrichment of markers associated with simple sugar, lipid and sterol turnover in the lowland species. However, longitudinal sampling shows that both species' microbiomes and metabolomes converge when hosts face similar dietary constraints, associated with low fruit availability in their habitats. By showing differences and convergence of diet-microbe co-metabolic fingerprints in two geographically isolated primate species, under specific dietary stimuli, we suggest that dietary constraints triggered during their adaptive radiation were potential factors behind the species-specific microbiome patterns observed in primates today. |
| تدمد: | 1751-7370 1751-7362 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83d0b30eb999270f1476ca199e0229fTest https://doi.org/10.1038/ismej.2015.146Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....c83d0b30eb999270f1476ca199e0229f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17517370 17517362 |
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