Assessing the extent of community spread caused by mink-derived SARS-CoV-2 variants
| العنوان: | Assessing the extent of community spread caused by mink-derived SARS-CoV-2 variants |
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| المؤلفون: | Yuhai Bi, George F. Gao, Liang Wang, Xavier Didelot |
| المصدر: | Innovation (New York, N.y.) The Innovation, Vol 2, Iss 3, Pp 100128-(2021) |
| بيانات النشر: | Elsevier BV, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | 0301 basic medicine, 2019-20 coronavirus outbreak, Science (General), Coronavirus disease 2019 (COVID-19), viruses, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), law.invention, Q1-390, 03 medical and health sciences, 0302 clinical medicine, human-to-human transmission, law, Report, biology.animal, 030212 general & internal medicine, Mink, skin and connective tissue diseases, Genetics, QL, Multidisciplinary, Phylogenetic tree, biology, SARS-CoV-2, fungi, mink, body regions, 030104 developmental biology, Transmission (mechanics), RA, RC |
| الوصف: | SARS-CoV-2 has recently been found to have spread from humans to minks and then to have transmitted back to humans. However, it is unknown to what extent the human-to-human transmission caused by the variant has reached. Here, we used publicly available SARS-CoV-2 genomic sequences from both humans and minks collected in Denmark and Netherlands, and combined phylogenetic analysis with Bayesian inference under an epidemiological model to trace the possibility of person-to-person transmission. The results showed that at least 12.5% of all people being infected with dominated mink-derived SARS-CoV-2 variants in Denmark and Netherlands were caused by human-to-human transmission, indicating this “back-to-human” SARS-CoV-2 variant has already caused human-to-human transmission. Our study also indicated the need for monitoring this mink-derived and other animal source “back-to-human” SARS-CoV-2 in future and that prevention and control measures should be tailored to avoid large-scale community transmission caused by the virus jumped between animals and humans. Graphical Abstract SARS-CoV-2 transmission from human to mink is not lineage specific. Mink-derived SARS-CoV-2 variants keep human-to-human transmission. At least 12.5% of patients with mink-derived SARS-CoV-2 were caused by human-to-human transmission. |
| وصف الملف: | application/pdf |
| تدمد: | 2666-6758 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df94996bcf429540d6de4d919ad88c78Test https://doi.org/10.1016/j.xinn.2021.100128Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....df94996bcf429540d6de4d919ad88c78 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 26666758 |
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