Microvascular Branching as a Determinant of Blood Flow by Intravital Particle Imaging Velocimetry

التفاصيل البيبلوغرافية
العنوان: Microvascular Branching as a Determinant of Blood Flow by Intravital Particle Imaging Velocimetry
المؤلفون: Jerry G. Myers, Krishnan Radhakrishnan, Mary B. Vickerman, Mark P Wernet, Patricia Parsons-Wingerter, Terri L. McKay
المصدر: The FASEB Journal. 21
بيانات النشر: Wiley, 2007.
سنة النشر: 2007
مصطلحات موضوعية: Chemistry, Maximum flow problem, Laminar flow, Blood flow, Anatomy, Particle imaging velocimetry, Branching (polymer chemistry), Biochemistry, Particle image velocimetry, Flow velocity, Genetics, Molecular Biology, Biotechnology, Biomedical engineering, A determinant
الوصف: The effects of microvascular branching on blood flow were investigated in vivo by microscopic particle imaging velocimetry (micro-PIV). We use micro-PIV to measure blood flow by tracking red blood cells (RBC) as the moving particles. Velocity flow fields, including flow pulsatility, were analyzed for the first four branching orders of capillaries, postcapillary venules and small veins of the microvascular network within the developing avian yolksac at embryonic day 5 (E5). Increasing volumetric flowrates were obtained from parabolic laminar flow profiles as a function of increasing vessel diameter and branching order. Maximum flow velocities increased approximately twenty-fold as the function of increasing vessel diameter and branching order compared to flow velocities of 100 - 150 micron/sec in the capillaries. Results from our study will be useful for the increased understanding of blood flow within anastomotic, heterogeneous microvascular networks.
تدمد: 1530-6860
0892-6638
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::139577e9e4ca39d8b83b7b5dc2273228Test
https://doi.org/10.1096/fasebj.21.5.a232Test
حقوق: OPEN
رقم الانضمام: edsair.doi...........139577e9e4ca39d8b83b7b5dc2273228
قاعدة البيانات: OpenAIRE