Brain metastasis from prostate small cell carcinoma: not to be neglected
| العنوان: | Brain metastasis from prostate small cell carcinoma: not to be neglected |
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| المؤلفون: | Erik J. van Lindert, Corrie E. Erasmus, Wim I.M. Verhagen, Carla Wauters |
| المصدر: | Canadian Journal of Neurological Sciences, 29, 375-7 Canadian Journal of Neurological Sciences, 29, 4, pp. 375-7 |
| سنة النشر: | 2002 |
| مصطلحات موضوعية: | PCA3, Male, Pathology, medicine.medical_specialty, Prostate Small Cell Carcinoma, Neuroendocrine differentiation, Small-cell carcinoma, Prostate, medicine, Humans, Carcinoma, Small Cell, Onderzoek Neurochirurgie, Aged, business.industry, Brain Neoplasms, Prostatic Neoplasms, General Medicine, Prostate-Specific Antigen, medicine.disease, Prognosis, Magnetic Resonance Imaging, Prostate-specific antigen, medicine.anatomical_structure, Neurology, Adenocarcinoma, Neurology (clinical), business, Tomography, X-Ray Computed, Brain metastasis |
| الوصف: | Background:Symptomatic brain metastases from prostatic carcinoma are rare (0.05% to 0.5%).Case report:A 70-year-old man presented with a homonymous hemianopsia due to brain metastatic prostatic carcinoma shortly before becoming symptomatic of prostatic disease. CT and MRI of the brain showed a tumour deep in the right hemisphere near the thalamus and involving the optic radiation.Results:Routine haematological and biochemical tests were normal. The prostate specific antigen level was low on two separate occasions. The prostatic and brain tumours showed identical appearances, namely of a poorly differentiated adenocarcinoma with neuroendocrine differentiation (small cell carcinoma).Conclusion:A literature review suggests that small cell carcinoma of the prostate is more likely to spread to the brain compared to adenocarcinoma and that brain metastases indicate a poor prognosis. The prostate gland should be remembered as a possible cause of brain metastases and that a normal serum prostate specific antigen does not exclude this diagnosis. |
| تدمد: | 0317-1671 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b406a9261b7447925e5f496414bfec30Test https://pubmed.ncbi.nlm.nih.gov/12463494Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....b406a9261b7447925e5f496414bfec30 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 03171671 |
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