المؤلفون: Chiung-Yi Yeh, Jun-Wei Su, Cherry Yin-Yi Chang, Chih-Yi Yang, Wu-Chou Lin, Chien-Chu Huang

المصدر: Taiwanese Journal of Obstetrics and Gynecology. 61:1061-1064

مصطلحات موضوعية: Obstetrics and Gynecology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::e548b163092f7db74e6fbc976509ac39Test
https://doi.org/10.1016/j.tjog.2022.01.005Test

المؤلفون: Wei Chun Chang, Lian Shung Yeh, Cherry Yin-Yi Chang, Yao Ching Hung, Wu Chou Lin, Kang Hsi Wu, Tze-Yi Lin

المصدر: Taiwanese Journal of Obstetrics & Gynecology, Vol 50, Iss 4, Pp 503-505 (2011)

مصطلحات موضوعية: medicine.medical_specialty, Lung Neoplasms, Yolk sac tumor, Adolescent, medicine.medical_treatment, GemOx, lcsh:Gynecology and obstetrics, Metastasis, Vulvar Yolk Sac Tumor, Vulvar Germ Cell Tumor, Carcinoma, Embryonal, Obstetrics and Gynaecology, medicine, Humans, lcsh:RG1-991, Chemotherapy, Vulvar Neoplasms, Vulvectomy, business.industry, Endodermal Sinus Tumor, Obstetrics and Gynecology, Vulvar cancer, medicine.disease, Combined Modality Therapy, Vulvar mass, Surgery, Radiation therapy, Embryonal carcinoma, Female, business, Peripheral blood stem cell transplantation

الوصف: Objective Vulvar cancer is rare in Eastern females, especially in pre- and peripubertal girls. The prognosis of vulvar cancer is poor and treatment is variable. Case Report A 14-year-old girl suffered from a left vulvar tenderness mass and underwent excision of the mass. The diagnosis of the pathology was vulvar yolk tumor with an embryonal carcinoma. After the vulvectomy, inguinal area lymph node dissection, chemotherapy (bleomycin, etoposide and cisplatin) treatment and radiotherapy, metastasis to lung was also noted after eight months. Resection of lung tumor was performed. She received chemotherapy with a combination of paclitaxel, ifosphamide and cisplatin (TIP) and received peripheral blood stem cell transplantation (PBSCT) twice and chemotherapy treatment of gemitabine and oxaliplatin (GEMOX). Up until now, the patient has been free of disease. Conclusion High-dose TIP and GEMOX chemotherapy plus PBSCT for bone marrow rescues could be considered to treat patients with metastatic malignant vulvar germ cell tumor after failed first-line chemotherapy and radiation.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e20bd358c36b8035a280b33554ca48d1Test
https://doi.org/10.1016/j.tjog.2011.10.018Test