التفاصيل البيبلوغرافية
| العنوان: |
A Practical and Scalable Preparation of Lusianthridin. |
| المؤلفون: |
Liao, Qi, Shi, Da-Yu, Xu, Hao, Zhang, Gui-Shan, Huang, Cheng, Tian, Ping, Lin, Guo-Qiang, Wang, Zhengtao, Wang, Yu-Hui |
| المصدر: |
Synlett; Jul2022, Vol. 33 Issue 11, p1087-1091, 5p |
| مصطلحات موضوعية: |
NUCLEOPHILIC substitution reactions, SUZUKI reaction |
| مستخلص: |
The efficient preparation of the stilbenoid lusianthridin is described. This synthesis relies on a Suzuki–Miyaura coupling and an intramolecular nucleophilic substitution as key reactions to construct the 9,10-dihydrophenanthrene core. The synthesis is completed in seven steps with a 13.2% overall yield, and each step can be conducted on a >20 gram scale. The route has provided 20 grams of lusianthridin for further biological activity studies. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
