The feasibility of prediction of same-limb kinematics using a single inertial measurement unit attached to the same limb has been demonstrated using machine learning. This study was performed to see if a single inertial measurement unit attached to the tibia can predict the opposite leg’s kinematics (cross-leg prediction). It also investigated if there is a minimal or smaller data set in a convolutional neural network model to predict lower extremity running kinematics under other running conditions and with what accuracy for the intra- and inter-participant situations. Ten recreational runners completed running exercises under five conditions, including treadmill running at speeds of 2, 2.5, 3, and 3.5 m/s and level-ground running at their preferred speed. A one-predict-all scheme was adopted to determine which running condition could be used to best predict a participant’s overall running kinematics. Running kinematic predictions were performed for intra- and inter-participant scenarios. Among the tested running conditions, treadmill running at 3 m/s was found to be the optimal condition for accurately predicting running kinematics under other conditions, with R2 values ranging from 0.880 to 0.958 and 0.784 to 0.936 for intra- and inter-participant scenarios, respectively. The feasibility of cross-leg prediction was demonstrated but with significantly lower accuracy than the same leg. The treadmill running condition at 3 m/s showed the highest intra-participant cross-leg prediction accuracy. This study proposes a novel, deep-learning method for predicting running kinematics under different conditions on a small training data set.
