المؤلفون: Robin Lorenz, Albert S. Reger, Jeong Joo Kim, Darren E. Casteel, Stefan T. Arold, Banumathi Sankaran, Choel Kim, Friedrich W. Herberg

المصدر: Structure (London, England : 1993), vol 24, iss 5
Kim, JJ; Lorenz, R; Arold, ST; Reger, AS; Sankaran, B; Casteel, DE; et al.(2016). Crystal Structure of PKG I:cGMP Complex Reveals a cGMP-Mediated Dimeric Interface that Facilitates cGMP-Induced Activation. Structure, 24(5), 710-720. doi: 10.1016/j.str.2016.03.009. Lawrence Berkeley National Laboratory: Lawrence Berkeley National Laboratory. Retrieved from: http://www.escholarship.org/uc/item/8q56g7g4Test

مصطلحات موضوعية: 0301 basic medicine, crystal structure, second messengers, 1.1 Normal biological development and functioning, allosteric activation, Allosteric regulation, Biophysics, Plasma protein binding, Molecular Dynamics Simulation, Crystallography, X-Ray, Article, 03 medical and health sciences, chemistry.chemical_compound, NO-cGMP signaling, Underpinning research, Structural Biology, Information and Computing Sciences, cyclic nucleotide-binding domain, Humans, 2.1 Biological and endogenous factors, Aetiology, Binding site, Protein kinase A, Cyclic GMP, Molecular Biology, Cyclic guanosine monophosphate, Cyclic GMP-Dependent Protein Kinase Type I, Crystallography, Binding Sites, 030102 biochemistry & molecular biology, Chemistry, Biological Sciences, Cell biology, Molecular Docking Simulation, 030104 developmental biology, Cyclic nucleotide-binding domain, cGMP-dependent protein kinase, small-angle X-ray scattering, Chemical Sciences, Second messenger system, cardiovascular system, X-Ray, Protein Multimerization, Protein Binding

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2fb2e3ab12b4c73bc1c9f951f34d814Test
https://doi.org/10.1016/j.str.2016.03.009Test

المؤلفون: Choel Kim, Chi Zhao, Jeong Joo Kim, Gilbert Huang, Albert S. Reger, Daniela Bertinetti, Rajeevan Selvaratnam, Friedrich W. Herberg, Darren E. Casteel, Giuseppe Melacini, Eui Whan Moon, James W. Pflugrath, Banumathi Sankaran, Bryan VanSchouwen, Robin Lorenz

المصدر: Structure. 22:116-124

مصطلحات موضوعية: Models, Molecular, Molecular Sequence Data, Phosphodiesterase 3, Gene Expression, Biology, Arginine, Crystallography, X-Ray, Article, Cyclic nucleotide, chemistry.chemical_compound, Leucine, Structural Biology, Catalytic Domain, Cyclic AMP, Escherichia coli, Humans, Amino Acid Sequence, Binding site, Cyclic nucleotide-gated ion channel, Cyclic GMP, Molecular Biology, Cyclic guanosine monophosphate, Cyclic GMP-Dependent Protein Kinase Type I, Binding Sites, CGMP binding, Recombinant Proteins, Kinetics, HEK293 Cells, chemistry, Biochemistry, Cyclic nucleotide-binding domain, Mutagenesis, Site-Directed, Biophysics, Thermodynamics, PDE10A, Sequence Alignment, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc76169bed1c8f7d0a7d81a6d9460755Test
https://doi.org/10.1016/j.str.2013.09.021Test

المؤلفون: Nikki Cheung, Susan S. Taylor, Choel Kim, Jian Wu, Jessica G.H. Bruystens, Juniper Pennypacker, Angela J. Boettcher, Donald A. Blumenthal, Alexandr P. Kornev, Jie Yang

المصدر: Structure. 19:265-276

مصطلحات موضوعية: Models, Molecular, Protein Conformation, Tetrameric protein, Stereochemistry, Cyclic AMP-Dependent Protein Kinase RIalpha Subunit, Protein subunit, Molecular Sequence Data, Allosteric regulation, Gene Expression, Cooperativity, Biology, Article, Protein structure, Allosteric Regulation, X-Ray Diffraction, Tetramer, Holoenzymes, Structural Biology, Catalytic Domain, Scattering, Small Angle, Cyclic AMP, Animals, Humans, Amino Acid Sequence, Molecular Biology, Sequence Homology, Amino Acid, Recombinant Proteins, Enzyme Activation, Kinetics, Protein Subunits, Crystallography, Mutation, CAMP binding, Protein Multimerization, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::463a5a46bfca7d1d0eda2e1b48834e38Test
https://doi.org/10.1016/j.str.2010.12.005Test

المؤلفون: J. Andrew McCammon, Justin Gullingsrud, Choel Kim, Susan S. Taylor

المصدر: Structure. 14(1):141-149

مصطلحات موضوعية: Models, Molecular, Conformational change, Protein Conformation, Stereochemistry, Chemistry, Cyclic AMP-Dependent Protein Kinase RIalpha Subunit, Protein subunit, Crystal structure, Plasma protein binding, Cyclic AMP-Dependent Protein Kinases, Protein Structure, Tertiary, Protein Subunits, Molecular dynamics, Protein structure, Cyclic nucleotide-binding domain, Structural Biology, Helix, Cyclic AMP, Humans, Computer Simulation, Molecular Biology, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fbfd14a5188ef45b4abf24a7faf05aaTest