The antifungal susceptibility of Candida albicans isolated from 2 groups of Thai patiens; AIDS patients and non-AIDS patients was investigated. Two hundread and seventeen C. albicans were isolated from the specimens from 54 AIDS patients and 163 non AIDS patients. All isolate were included in the antifungal susceptibility test against amphotericin B, fluconazole, ketoconazole and nystatin. A hundred isolates were randomly selected from both groups for the electrophoretic karyotypes determination.    There was not much difference in the value of Mic, MIC50 and MIC90 of all antifungal agent for C. albicans isolates between AIDS and non-AIDS patients. The amphoter B MIC for 61.0% if AIDS isolates and 71.0% of non-AIDS isolates were >0.5 mg/l, while ketoconazole MIC for 94.4% of AIDS and 74.9% of non-AIDS isolates were >0.125 mg/l and fluconazole MIC of 100% of AIDS and non-AIDS isolates were 2.0 mg/l. For nystatin, the MIC for more than 90% of both isolates was
