التفاصيل البيبلوغرافية
| العنوان: |
HTLV-1 cosmopolitan and HTLV-2 subtype b among pregnant women of non-endemic areas of Argentina. |
| المؤلفون: |
Berini, Carolina A., Delfino, Cecilia, Torres, Oscar, García, Gabriela, Espejo, Rogelio, Pianciola, Luis, Juarez, Mirna, Arribere, Graciela, Nadal, Mónica, Eirin, Maria E., Biglione, Mirna M. |
| المصدر: |
Sexually Transmitted Infections; Jun2013, Vol. 89 Issue 4, p333-335, 3p, 1 Chart |
| مصطلحات موضوعية: |
T cells, HIV, HEPATITIS B, HEPATITIS B virus, TRYPANOSOMA cruzi, TREPONEMA pallidum, TOXOPLASMA gondii, PREGNANCY complications |
| مستخلص: |
Objectives The objective of this study was to estimate the prevalence of human T cell lymphotropic virus (HTLV)-1/2, HIV-1, hepatitis B virus (HBV), Trypanosoma cruzi, Treponema pallidum and Toxoplasma gondii infections and to identify the subtypes/subgroups of HTLV-1/2 among pregnant women (PW) from non-endemic provinces of Argentina. Methods Methods A total of 2403 samples were screened for HTLV-1/2 and confirmed by western blot and PCR. The long terminal repeat (LTR) of HTLV-1 and HTLV-2 were amplified. Phylogenetic analysis was performed by Neighbour Joining by using molecular evolutionary genetics analysis (MEGA) 4.0. Results Among a total of 2403 PW studied, 6 (0.25%) tested positive for HTLV-1/2 (3 HTLV-1 (0.12%) and 3 HTLV-2 (0.12%)). The total prevalence when distributed by province was 0.3% (3/804) for Buenos Aires (BA), 0.4% (1/241) for BA surroundings, 0.1% (1/707) for Neuquen and 1.0% (1/95) for Ushuaia. In San Juan, no PW were HTLV-1/2 positive. The prevalence was similar when compared with rates among blood donors of the same areas and years. The phylogenetic analysis classified one sequence as HTLV-1 aA and one as HTLV- 2b. The prevalence of HIV-1, HBV, T cruzi, T pallidum and T gondii was 0.6%, 0.2%, 1.4%, 1.2% and 20.9%, respectively. One case of HTLV-1/HIV-1 and one of HTLV-2/HIV-1 co-infection were detected. Conclusions HTLV-1/2, which have been associated with different diseases, are circulating among PW of Argentina, even in non-endemic areas. Therefore, testing should be recommended in women who have risk factors for these infections given that the majority of HTLV-1/2 mother to child transmission can be prevented by the avoidance of breast feeding. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
