Recent Advances in the Development of Biosensors for Malaria Diagnosis
| العنوان: | Recent Advances in the Development of Biosensors for Malaria Diagnosis |
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| المؤلفون: | Prosper Kanyong, Francis D. Krampa, Yaw Aniweh, Gordon A. Awandare |
| المصدر: | Sensors, Vol 20, Iss 3, p 799 (2020) Sensors (Basel, Switzerland) |
| بيانات النشر: | MDPI AG, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Computer science, Protozoan Proteins, Biosensing Techniques, Review, 02 engineering and technology, lcsh:Chemical technology, 01 natural sciences, Biochemistry, Analytical Chemistry, chemistry.chemical_compound, Glutamate Dehydrogenase, Fructose-Bisphosphate Aldolase, lcsh:TP1-1185, Malaria, Falciparum, Instrumentation, biology, Hemozoin, 021001 nanoscience & nanotechnology, Atomic and Molecular Physics, and Optics, 3. Good health, clinical diagnosis, 0210 nano-technology, Hemeproteins, Plasmodium falciparum, Early detection, Antigens, Protozoan, Computational biology, medical devices, Lactate dehydrogenase, parasitic diseases, medicine, Humans, Diagnostic biomarker, Electrical and Electronic Engineering, L-Lactate Dehydrogenase, Diagnostic Tests, Routine, Glutamate dehydrogenase, 010401 analytical chemistry, Aldolase A, biology.organism_classification, medicine.disease, biosensors, 0104 chemical sciences, chemistry, Clinical diagnosis, biology.protein, malaria biomarkers, biosensing, Biosensor, Malaria |
| الوصف: | The impact of malaria on global health has continually prompted the need to develop more effective diagnostic strategies that could overcome deficiencies in accurate and early detection. In this review, we examine the various biosensor-based methods for malaria diagnostic biomarkers, namely; Plasmodium falciparum histidine-rich protein 2 (PfHRP-2), parasite lactate dehydrogenase (pLDH), aldolase, glutamate dehydrogenase (GDH), and the biocrystal hemozoin. The models that demonstrate a potential for field application have been discussed, looking at the fabrication and analytical performance characteristics, including (but not exclusively limited to): response time, sensitivity, detection limit, linear range, and storage stability, which are first summarized in a tabular form and then described in detail. The conclusion summarizes the state-of-the-art technologies applied in the field, the current challenges and the emerging prospects for malaria biosensors. |
| اللغة: | English |
| تدمد: | 1424-8220 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a846a7f06f611d466c348bfad0dce96Test https://www.mdpi.com/1424-8220/20/3/799Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....1a846a7f06f611d466c348bfad0dce96 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14248220 |
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