دورية أكاديمية

Frailty is associated with susceptibility and severity of pneumonia in older adults (A JAGES multilevel cross-sectional study).

التفاصيل البيبلوغرافية
العنوان: Frailty is associated with susceptibility and severity of pneumonia in older adults (A JAGES multilevel cross-sectional study).
المؤلفون: Iwai-Saito, Kousuke1 anayoshi@med.niigata-u.ac.jp, Shobugawa, Yugo2, Aida, Jun3,4, Kondo, Katsunori5,6
المصدر: Scientific Reports. 4/12/2021, Vol. 11 Issue 1, p1-10. 10p.
مصطلحات موضوعية: *PNEUMONIA, *DISEASE susceptibility, *HEALTH of older people, *MORTALITY, *HOSPITAL patients
مستخلص: Pneumonia is a leading cause of mortality among older adults worldwide. Recently, several studies reported that frailty was associated with mortality among older adults hospitalized due to respiratory infectious diseases, including pneumonia. However, it is unknown whether frailty is associated with susceptibility to and severity of pneumonia in functionally-independent community-dwelling older adults. In this study, we examined whether frailty increased the susceptibility to pneumonia and hospitalization in older adults. We used cross-sectional data from the Japan Gerontological Evaluation Study; the data was collected by using mail-based, self-reported questionnaires from 177,991 functionally-independent community-dwelling older adults aged ≥ 65 years. Our results showed that frailty was significantly associated with both occurrence of and hospitalization due to pneumonia after adjustments with covariates; (Preference ratio {PR} 1.92, 95% confidence interval {95% CI} [1.66–2.22] and PR 1.80, 95% CI [1.42–2.28], respectively, p < 0.001 for the both). Pre-frailty was associated only with the occurrence of pneumonia. Besides, the instrumental activity of daily living, physical strength, nutrition status, oral function, homeboundness, and depression status in frail older adults were associated with either or both occurrence of and hospitalization due to pneumonia. Our results suggest that frailty influenced the susceptibility to and severity of pneumonia in older adults. [ABSTRACT FROM AUTHOR]
قاعدة البيانات: Academic Search Index
الوصف
تدمد:20452322
DOI:10.1038/s41598-021-86854-3